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AXL Products

(AXL Receptor tyrosine Kinase (AXL))

Categories

The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

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Featured AXL Categories

AXL Antibodies

High quality antibodies with extensive validation data.

AXL ELISA Kits

Reliable ELISA kits for a wide range of species.

AXL Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended AXL Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, RNAi
Validations
  • (1)
  • (6)
Cat. No. ABIN560017
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, IF
Validations
  • (5)
Cat. No. ABIN7265804
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (4)
Cat. No. ABIN7265803
Quantity 100 μL
Datasheet Datasheet

Recommended AXL ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954023
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954024
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1889307
Quantity 96 tests
Datasheet Datasheet

Recommended AXL Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (5)
Cat. No. ABIN7273881
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (5)
Cat. No. ABIN7273880
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7273884
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our AXL products

Novoyatleva, Rai, Kojonazarov, Veeroju, Ben-Batalla, Caruso, Shihan, Presser, Götz, Lepper, Herpel, Manaud, Perros, Gall, Ghofrani, Weissmann, Grimminger, Wharton, Wilkins, Upton, Loges, Morrell et al.: "Deficiency of Axl aggravates pulmonary arterial hypertension via BMPR2. ..." in: Communications biology, Vol. 4, Issue 1, pp. 1002, (2021) (PubMed).

Dumas, Naudin, Martin-Lannerée, Izac, Casetti, Mansier, Rousseau, Artus, Dufossée, Giese, Dubus, Pigneux, Praloran, Bidet, Villacreces, Guitart, Milpied, Kosmider, Vigon, Desplat, Dusanter-Fourt et al.: "Hematopoietic niche drives FLT3-ITD acute myeloid leukemia resistance to quizartinib via STAT5- and hypoxia- dependent up-regulation of AXL. ..." in: Haematologica, (2019) (PubMed).

Zapatero-Belinchón, Dietzel, Dolnik, Döhner, Costa, Hertel, Veselkova, Kirui, Klintworth, Manns, Pöhlmann, Pietschmann, Krey, Ciesek, Gerold, Sodeik, Becker, von Hahn: "Characterization of the Filovirus-Resistant Cell Line SH-SY5Y Reveals Redundant Role of Cell Surface Entry Factors." in: Viruses, Vol. 11, Issue 3, (2019) (PubMed).

Kasikara, Davra, Calianese, Geng, Spires, Quigley, Wichroski, Sriram, Suarez-Lopez, Yaffe, Kotenko, De Lorenzo, Birge: "Pan-TAM Tyrosine Kinase Inhibitor BMS-777607 Enhances Anti-PD-1 mAb Efficacy in a Murine Model of Triple-Negative Breast Cancer." in: Cancer research, Vol. 79, Issue 10, pp. 2669-2683, (2019) (PubMed).

Sinik, Minson, Tentler, Carrico, Bagby, Robinson, Kami, Burstyn-Cohen, Eckhardt, Wang, Frye, Earp, DeRyckere, Graham: "Inhibition of MERTK Promotes Suppression of Tumor Growth in BRAF Mutant and BRAF Wild-Type Melanoma." in: Molecular cancer therapeutics, Vol. 18, Issue 2, pp. 278-288, (2019) (PubMed).

Mills, Quinn, Roach, Palisoul, Nguyen, Noia, Guo, Fazal, Mutch, Wickline, Pan, Fuh: "p5RHH nanoparticle-mediated delivery of AXL siRNA inhibits metastasis of ovarian and uterine cancer cells in mouse xenografts." in: Scientific reports, Vol. 9, Issue 1, pp. 4762, (2019) (PubMed).

Santamaria-Barria, Zeng, Greer, Beckman, Seifert, Cohen, Zhang, Crawley, Green, Loo, Maltbaek, DeMatteo: "Csf1r or Mer inhibition delays liver regeneration via suppression of Kupffer cells." in: PLoS ONE, Vol. 14, Issue 5, pp. e0216275, (2019) (PubMed).

Jardine, Wiscombe, Reynolds, McDonald, Fuller, Green, Filby, Forrest, Ruchaud-Sparagano, Scott, Collin, Haniffa, Simpson: "Lipopolysaccharide inhalation recruits monocytes and dendritic cell subsets to the alveolar airspace." in: Nature communications, Vol. 10, Issue 1, pp. 1999, (2019) (PubMed).

Strange, Jiyarom, Pourhabibi Zarandi, Xie, Baker, Sadri-Ardekani, Shi, Verma: "Axl Promotes Zika Virus Entry and Modulates the Antiviral State of Human Sertoli Cells." in: mBio, Vol. 10, Issue 4, (2019) (PubMed).

Carestia, Mena, Olexen, Ortiz Wilczyñski, Negrotto, Errasti, Gómez, Jenne, Carrera Silva, Schattner: "Platelets Promote Macrophage Polarization toward Pro-inflammatory Phenotype and Increase Survival of Septic Mice." in: Cell reports, Vol. 28, Issue 4, pp. 896-908.e5, (2019) (PubMed).

Synonyms and alternative names related to AXL

AXL receptor tyrosine kinase (AXL), AXL receptor tyrosine kinase (Axl), Axl receptor tyrosine kinase (Axl), AI323647, Ark, JTK11, Tyro7, UFO, Ufo

Protein level used designations for AXL

  • AXL oncogene
  • AXL transforming sequence/gene
  • tyrosine-protein kinase receptor UFO
  • adhesion-related kinase
  • ufo oncogene homolog
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