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Browse our DDR2 (DDR2) ELISA Kits

Full name:
Discoidin Domain Receptor tyrosine Kinase 2 ELISA Kits (DDR2)
On www.antibodies-online.com are 5 Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) ELISA Kits from 3 different suppliers available. Additionally we are shipping DDR2 Antibodies (97) and DDR2 Proteins (30) and many more products for this protein. A total of 145 DDR2 products are currently listed.
Synonyms:
AW495251, ddr2, MIG20a, NTRKR3, si:ch211-193c2.1, TKT, Tyro10
list all ELISA KIts Gene Name GeneID UniProt
DDR2 18214 Q62371
DDR2 4921 Q16832
Rat DDR2 DDR2 685781  

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DDR2 (DDR2) ELISA Kits by Reactivity

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Mouse (Murine) Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) interaction partners

  1. DDR2 mutation can drive lung cancer initiation in vivo and provide a novel mouse model for lung cancer therapeutics studies.

  2. Study showed that Nrp1 (show NRP1 ELISA Kits) expression paralleled with that of DDR2 during osteoblast differentiation. Nrp1 (show NRP1 ELISA Kits) assisted the promoting role of DDR2 in osteoblast differentiation, via activation of DDR2-mediated downstream signaling.

  3. Data show that discoidin domain receptor (DDR (show DDR1 ELISA Kits)) 2 siRNA-mediated suppression of extracellular regulated kinase (ERK) 1 (show MAPK3 ELISA Kits) and 2 and nuclear factor of kappa B (NF-kappaB (show NFKB1 ELISA Kits)) could down-regulate the expressions of matrix metalloproteinase (MMP) 2 (show MMP2 ELISA Kits) and 9.

  4. RESULTS Data show that DDR2 (discoidin domain receptor 2) suppresses osteoclast differentiation and activity.

  5. DDR2 signaling regulates cell proliferation and extracellular matrix synthesis, which are key aspects of fibroblast contribution to tissue healing [review]

  6. Germline deletion of the DDR2 results in smaller hearts, shorter cardiomyocytes, lower interstitial cardiac collagen density and abnormalities in cardiac function.

  7. Taken together, our data demonstrated that DDR2 might play a systemic role in the regulation of body size thorough skeletal formation and fat metabolism.

  8. Loss of DDR2 suppresses tumor angiogenesis and tumor metastasis to the lung.

  9. DDR2 is involved in the collagen I-induced IL-12 (show IL12A ELISA Kits) production via NF-kappaB (show NFKB1 ELISA Kits) and JNK (show MAPK8 ELISA Kits) pathway

  10. these data demonstrated that DDR2 might play a local and essential role in the proliferation of chondrocytes.

Human Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) interaction partners

  1. DDR2 Missense mutation is associated with spondylo-meta-epiphyseal dysplasia, short limb-abnormal calcification type.

  2. Data suggest SCl2 (Streptococcus pyogenes) binds to DDR (DDR1, DDR2) ectodomain w/o stimulating receptor signaling; here, protein engineering was used to construct SCl (show KRT7 ELISA Kits)-like proteins that inhibit collagen-DDR (show DDR1 ELISA Kits) interactions and macrophage migration.

  3. DDR2 plays an important role in promoting hepatocellular carcinoma cell invasion and migration by stabilizing SNA1 (show SNAI1 ELISA Kits).

  4. The inhibition of DDR2 by RNA interference suppressed in vivo and in vitro growth of human hepatocellular carcinoma cells.

  5. Report correlation between increased radiographic grade of knee osteoarthritis and decreased proportion of cartilage stained for DDR2.

  6. Identified are 3 Single Nucleotide Polymorphisms in DDR2 significantly associated with hip bone mineral density in the Chinese population.

  7. Defective Ca(2 (show CA2 ELISA Kits)+) binding in a conserved binding site causes incomplete N-glycan processing and endoplasmic reticulum trapping of DDR1 and DDR2 receptors.

  8. Data show that discoidin domain receptor 2 (DDR2) is linked to a polyubiquitin (Ub) chain predominantly through lysine K27 conjugation and slightly through K33.

  9. In ADSCC patients, DDR2 mutation coexisted with G12C substitution in KRAS gene.

  10. peptide delivered by the AuNP-Apt system inhibited cancer cell proliferation and invasion mediated by DDR2 activation

DDR2 Antigen Profile

Antigen Summary

Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein.

Alternative names and synonyms associated with DDR2

  • discoidin domain receptor tyrosine kinase 2 (DDR2) Elisa Kit
  • discoidin domain receptor family, member 2b (ddr2b) Elisa Kit
  • discoidin domain receptor family, member 2 (LOC100356982) Elisa Kit
  • discoidin domain receptor family, member 2 (Ddr2) Elisa Kit
  • discoidin domain receptor tyrosine kinase 2 (Ddr2) Elisa Kit
  • AW495251 Elisa Kit
  • ddr2 Elisa Kit
  • MIG20a Elisa Kit
  • NTRKR3 Elisa Kit
  • si:ch211-193c2.1 Elisa Kit
  • TKT Elisa Kit
  • Tyro10 Elisa Kit

Protein level used designations for DDR2

discoidin domain receptor tyrosine kinase 2 , discoidin domain receptor family, member 2 , CD167 antigen-like family member B , discoidin domain receptor 2 , discoidin domain-containing receptor 2 , neurotrophic tyrosine kinase, receptor-related 3 , receptor protein-tyrosine kinase TKT , tyrosine-protein kinase TYRO10 , cell migration-inducing protein 20 , discoidin domain-containing receptor tyrosine kinase 2 , hydroxyaryl-protein kinase , migration-inducing gene 16 protein , neurotrophic tyrosine kinase receptor related 3 , tyrosylprotein kinase , CD167b antigen , tyrosine-protein kinase TYRO 10

GENE ID SPECIES
457467 Pan troglodytes
565333 Danio rerio
100356982 Oryctolagus cuniculus
18214 Mus musculus
4921 Homo sapiens
685781 Rattus norvegicus
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