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Browse our anti-PDGFB (PDGFB) Antibodies

Full name:
anti-Platelet-Derived Growth Factor beta Polypeptide Antibodies (PDGFB)
On are 111 Platelet-Derived Growth Factor beta Polypeptide (PDGFB) Antibodies from 29 different suppliers available. Additionally we are shipping PDGFB Kits (51) and PDGFB Proteins (37) and many more products for this protein. A total of 206 PDGFB products are currently listed.
c-sis, PDGF-2, PDGF-B, PDGF2, SIS, SSV
list all antibodies Gene Name GeneID UniProt
PDGFB 18591 P31240
PDGFB 5155 P01127
PDGFB 24628 Q05028

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Most Popular Reactivities for anti-PDGFB (PDGFB) Antibodies

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anti-Mouse (Murine) PDGFB Antibodies:

anti-Human PDGFB Antibodies:

anti-Rat (Rattus) PDGFB Antibodies:

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Top referenced anti-PDGFB Antibodies

  1. Human Polyclonal PDGFB Primary Antibody for IF (p), IHC (p) - ABIN725990 : Morita, Furube, Mannari, Okuda, Tatsumi, Wanaka, Miyata: Vascular endothelial growth factor-dependent angiogenesis and dynamic vascular plasticity in the sensory circumventricular organs of adult mouse brain. in Cell and tissue research 2015 (PubMed)
    Show all 4 references for ABIN725990

  2. Human Polyclonal PDGFB Primary Antibody for IF, WB - ABIN388460 : Müller, Richter, Rinas: Kinetics control preferential heterodimer formation of platelet-derived growth factor from unfolded A- and B-chains. in The Journal of biological chemistry 2003 (PubMed)
    Show all 4 references for ABIN388460

  3. Cow (Bovine) Polyclonal PDGFB Primary Antibody for IHC, WB - ABIN2787714 : Chadjichristos, Morel, Derouette, Sutter, Roth, Brisset, Bochaton-Piallat, Kwak: Targeting connexin 43 prevents platelet-derived growth factor-BB-induced phenotypic change in porcine coronary artery smooth muscle cells. in Circulation research 2008 (PubMed)

  4. Human Polyclonal PDGFB Primary Antibody for EIA, Func - ABIN116211 : Tan, Pal, Tan, Wong, Tam, Teo, Chong, Tan, Goh, Tang, Cheung, Tan: Regulation of cell proliferation and migration by TAK1 via transcriptional control of von Hippel-Lindau tumor suppressor. in The Journal of biological chemistry 2009 (PubMed)

  5. Human Monoclonal PDGFB Primary Antibody for CyTOF, FACS - ABIN258832 : Schito, Rey, Tafani, Zhang, Wong, Russo, Russo, Semenza: Hypoxia-inducible factor 1-dependent expression of platelet-derived growth factor B promotes lymphatic metastasis of hypoxic breast cancer cells. in Proceedings of the National Academy of Sciences of the United States of America 2012 (PubMed)

  6. Human Polyclonal PDGFB Primary Antibody for IHC (fro), IHC (p) - ABIN115468 : van Steensel, Paridaens, van Meurs, van Hagen, van den Bosch, Kuijpers, Drexhage, Hooijkaas, Dik: Orbit-infiltrating mast cells, monocytes, and macrophages produce PDGF isoforms that orchestrate orbital fibroblast activation in Graves' ophthalmopathy. in The Journal of clinical endocrinology and metabolism 2012 (PubMed)

More Antibodies against PDGFB Interaction Partners

Mouse (Murine) Platelet-Derived Growth Factor beta Polypeptide (PDGFB) interaction partners

  1. loss-of-function mutations in PDGFB or PDGFRB (show PDGFRB Antibodies) cause Primary Familial Brain Calcification.

  2. Results suggest that regional Pax3 (show PAX3 Antibodies) expression not only marks a novel subset of High-grade Brainstem Glioma but also contributes to PDGF-B-induced brainstem gliomagenesis

  3. High PDGFB expression is associated with liver fibrosis.

  4. Increased expression of STAT5b (show STAT5B Antibodies) + PDGFB led to increased expression of downstream STAT5b (show STAT5B Antibodies) targets.

  5. Platelets produce PDGFB to activate stellate cells and promote fibrosis in MDR2 (show ABCB4 Antibodies)-null mice.

  6. The endogenous levels of PDGF (show PDGFA Antibodies)-BB, increases CD31 (show PECAM1 Antibodies)(hi)endomucin (show EMCN Antibodies)(hi) vessel number and stimulates bone formation in ovariectomy mice.

  7. These findings thus implicate a novel role of PDGF (show PDGFA Antibodies)-BB in the migration of pericytes, resulting in loss of pericyte coverage from the endothelium with a subsequent breach of the blood-brain barrier

  8. The data indicate a dual role of Lhx2 (show LHX2 Antibodies) during EMT (show ITK Antibodies) and tumor progression: by inducing the expression of PDGF-B, Lhx2 (show LHX2 Antibodies) provokes an autocrine PDGF-B/PDGFRbeta loop required for cell migration, invasion and metastatic dissemination

  9. The signaling pathways of VEGF (show VEGFA Antibodies) and PDGF (show PDGFA Antibodies) are crucial mediators for determining proliferation of endothelial cells and oligodendrocytes in the neurohypophysis of adult mice.

  10. Our findings demonstrate, for the first time, that Shh (show SHH Antibodies) is involved in PDGF (show PDGFA Antibodies)-BB-induced smooth muscle cell migration and recruitment of mural cells into neovessels

Human Platelet-Derived Growth Factor beta Polypeptide (PDGFB) interaction partners

  1. this study shows that the expression of PDGFB is significantly downregulated in keloid fibroblasts compared to normal human fibroblasts

  2. this study demonstrated that knockdown of SCARA5 (show SCARA5 Antibodies) inhibits PDGFBBinduced HASMC proliferation and migration through suppression of the PDGF (show PDGFA Antibodies) signaling pathway.

  3. The simultaneous action of PDGF-B/PDGFRbeta and VEGF165b on the same type of receptor may explain the resistance to antiangiogenic therapy, which depends on the degree of modulation of PDGFRbeta phosphorylation.

  4. The expression of angiogenesis markers VEGF-A (show VEGFA Antibodies), VEGFR (show KDR Antibodies), PDGFbetabeta, PDGFR (show PDGFRB Antibodies), CCND1 (show CCND1 Antibodies) and CA9 (show CA9 Antibodies) was assessed by immunohistochemistry and correlated with overall survival and progression-free survival in patients with renal cell carcinoma (show MOK Antibodies) undergoing therapy with Sunitinib, but no correlation was found between expression of angiogenesis markers and clinical outcome.

  5. ore than 65% of cases had PDGF (show PDGFA Antibodies)-BB mRNA amplification, confirming immunohistochemical results. We herein validated PDGF (show PDGFA Antibodies)-BB as a potential therapeutic and prognostic tool of ovarian cancer aggressiveness.

  6. Case Report: congenital atrophic dermatofibrosarcoma protuberans with COL1A1-PDGFB rearrangement.

  7. Loss of Nf2 (show NF2 Antibodies) and Cdkn2a (show CDKN2A Antibodies)/b have synergistic effects with PDGF-B overexpression promoting meningioma malignant transformation.

  8. Human uPAR (show PLAUR Antibodies) activation and its association with beta1-integrin are required for PDGF (show PDGFA Antibodies)-AB-induced migration.

  9. Placental endothelial cell-derived PDGF (show PDGFA Antibodies)-BB recruits human placental multipotent mesenchymal stromal cells involved in vascular development via PDGFR-beta (show PDGFRB Antibodies)/STAT3 (show STAT3 Antibodies) activation

  10. Suggest that PDGF-B signaling may play a role in endothelial and cardiomyocyte recovery from ischemia reperfusion injury after heart transplantation.

Cow (Bovine) Platelet-Derived Growth Factor beta Polypeptide (PDGFB) interaction partners

  1. Study suggest that PDGF-B is induced by hypoxia and protects against apoptosis via the PI3K/Akt (show AKT1 Antibodies)/Stat3 (show STAT3 Antibodies) signaling pathway.

  2. PDGF-B transcription is increased by Nuclear Factor Kappa B

  3. up-regulated by Angiotensin II in retinal pericytes; results suggest that Ang II (show AGT Antibodies)-type 1 receptor interaction could stimulate PDGF-B gene expression in cultured retinal pericytes through intracellular reactive oxygen species generation

  4. PEDF promotes growth of pericytes through autocrine production of PDGFB.

  5. Hypoxia enhances PDGF-B paracrine interactions between glomerular endothelial and mesangial cells.

PDGFB Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Alternative names and synonyms associated with PDGFB

  • platelet-derived growth factor beta polypeptide (PDGFB) antibody
  • platelet derived growth factor, B polypeptide (Pdgfb) antibody
  • platelet-derived growth factor beta polypeptide (Pdgfb) antibody
  • c-sis antibody
  • PDGF-2 antibody
  • PDGF-B antibody
  • PDGF2 antibody
  • SIS antibody
  • SSV antibody

Protein level used designations for PDGFB

platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) , PDGF subunit B , PDGF-2 , c-sis , platelet-derived growth factor B chain , platelet-derived growth factor beta polypeptide , platelet-derived growth factor subunit B , proto-oncogene c-Sis , PDGF, B chain , becaplermin , platelet-derived growth factor 2 , platelet-derived growth factor, beta polypeptide (oncogene SIS) , Platelet-derived growth factor, same as Sis (Simian sarcoma viral oncogene homologue, c-sis) , pdgf protein , platelet derived growth factor, B polypeptide , platelet-derived growth factor B , v-sis platelet-derived growth factor beta polypeptide (simian sarcoma viral oncogene homolog) , platelet-derived growth factor B subunit

100228287 Taeniopygia guttata
18591 Mus musculus
5155 Homo sapiens
24628 Rattus norvegicus
100126843 Sus scrofa
442986 Canis lupus familiaris
540106 Bos taurus
100731469 Cavia porcellus
374128 Gallus gallus
443545 Ovis aries
Selected quality suppliers for anti-PDGFB (PDGFB) Antibodies
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