Browse our anti-PDGFB (PDGFB) Antibodies

Full name:
anti-Platelet-Derived Growth Factor beta Polypeptide Antibodies (PDGFB)
On www.antibodies-online.com are 87 Platelet-Derived Growth Factor beta Polypeptide (PDGFB) Antibodies from 30 different suppliers available. Additionally we are shipping PDGFB Kits (62) and PDGFB Proteins (42) and many more products for this protein. A total of 198 PDGFB products are currently listed.
Synonyms:
c-sis, PDGF-2, PDGF-B, PDGF2, SIS, SSV
list all antibodies Gene Name GeneID UniProt
PDGFB 18591 P31240
PDGFB 5155 P01127
PDGFB 24628 Q05028

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Most Popular Reactivities for anti-PDGFB (PDGFB) Antibodies

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anti-Mouse (Murine) PDGFB Antibodies:

anti-Human PDGFB Antibodies:

anti-Rat (Rattus) PDGFB Antibodies:

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Top referenced anti-PDGFB Antibodies

  1. Human Polyclonal PDGFB Primary Antibody for IF (p), IHC (p) - ABIN725990 : Morita, Furube, Mannari, Okuda, Tatsumi, Wanaka, Miyata: Vascular endothelial growth factor-dependent angiogenesis and dynamic vascular plasticity in the sensory circumventricular organs of adult mouse brain. in Cell and tissue research 2015 (PubMed)
    Show all 4 references for 725990

  2. Human Polyclonal PDGFB Primary Antibody for IF, WB - ABIN388460 : Müller, Richter, Rinas: Kinetics control preferential heterodimer formation of platelet-derived growth factor from unfolded A- and B-chains. in The Journal of biological chemistry 2003 (PubMed)
    Show all 4 references for 388460

  3. Cow (Bovine) Polyclonal PDGFB Primary Antibody for IHC, WB - ABIN2787714 : Chadjichristos, Morel, Derouette, Sutter, Roth, Brisset, Bochaton-Piallat, Kwak: Targeting connexin 43 prevents platelet-derived growth factor-BB-induced phenotypic change in porcine coronary artery smooth muscle cells. in Circulation research 2008 (PubMed)

  4. Human Monoclonal PDGFB Primary Antibody for CyTOF, FACS - ABIN258832 : Schito, Rey, Tafani, Zhang, Wong, Russo, Russo, Semenza: Hypoxia-inducible factor 1-dependent expression of platelet-derived growth factor B promotes lymphatic metastasis of hypoxic breast cancer cells. in Proceedings of the National Academy of Sciences of the United States of America 2012 (PubMed)

  5. Human Polyclonal PDGFB Primary Antibody for IHC (fro), IHC (p) - ABIN115468 : van Steensel, Paridaens, van Meurs, van Hagen, van den Bosch, Kuijpers, Drexhage, Hooijkaas, Dik: Orbit-infiltrating mast cells, monocytes, and macrophages produce PDGF isoforms that orchestrate orbital fibroblast activation in Graves' ophthalmopathy. in The Journal of clinical endocrinology and metabolism 2012 (PubMed)

  6. Human Polyclonal PDGFB Primary Antibody for EIA, Func - ABIN116211 : Tan, Pal, Tan, Wong, Tam, Teo, Chong, Tan, Goh, Tang, Cheung, Tan: Regulation of cell proliferation and migration by TAK1 via transcriptional control of von Hippel-Lindau tumor suppressor. in The Journal of biological chemistry 2009 (PubMed)

More Antibodies against PDGFB Interaction Partners

Mouse (Murine) Platelet-Derived Growth Factor beta Polypeptide (PDGFB) interaction partners

  1. PDGF-B-PDGFRbeta signaling plays a significant role in the development of adipose tissue neovascularization.

  2. data suggest that the stronger fibrotic effect generated by Pdgfa (show PDGFA Antibodies) overexpression was mediated by Pdgfralpha in cardiac interstitial mesenchymal cells

  3. loss-of-function mutations in PDGFB or PDGFRB (show PDGFRB Antibodies) cause Primary Familial Brain Calcification.

  4. Results suggest that regional Pax3 (show PAX3 Antibodies) expression not only marks a novel subset of High-grade Brainstem Glioma but also contributes to PDGF-B-induced brainstem gliomagenesis

  5. High PDGFB expression is associated with liver fibrosis.

  6. Increased expression of STAT5b (show STAT5B Antibodies) + PDGFB led to increased expression of downstream STAT5b (show STAT5B Antibodies) targets.

  7. Platelets produce PDGFB to activate stellate cells and promote fibrosis in MDR2 (show ABCB4 Antibodies)-null mice.

  8. The endogenous levels of PDGF (show PDGFA Antibodies)-BB, increases CD31 (show PECAM1 Antibodies)(hi)endomucin (show EMCN Antibodies)(hi) vessel number and stimulates bone formation in ovariectomy mice.

  9. These findings thus implicate a novel role of PDGF (show PDGFA Antibodies)-BB in the migration of pericytes, resulting in loss of pericyte coverage from the endothelium with a subsequent breach of the blood-brain barrier

  10. The data indicate a dual role of Lhx2 (show LHX2 Antibodies) during EMT (show ITK Antibodies) and tumor progression: by inducing the expression of PDGF-B, Lhx2 (show LHX2 Antibodies) provokes an autocrine PDGF-B/PDGFRbeta loop required for cell migration, invasion and metastatic dissemination

Human Platelet-Derived Growth Factor beta Polypeptide (PDGFB) interaction partners

  1. Insulin (show INS Antibodies) treatment caused sustained Akt (show AKT1 Antibodies) activity, whereas EGF (show EGF Antibodies) or PDGF (show PDGFA Antibodies)-AA promoted transient signaling; PDGF (show PDGFA Antibodies)-BB produced sustained responses at higher concentrations.Transient responses to EGF (show EGF Antibodies) were caused by negative feedback at the receptor level, as a second treatment yielded minimal responses, whereas parallel exposure to IGF-I (show IGF1 Antibodies) caused full Akt (show AKT1 Antibodies) activation

  2. high-throughput affinity plasma proteomic profiling is a valuable research strategy to identify potential candidate biomarkers for thrombosis-related disorders, and our study suggests a novel association of PDGFB plasma levels with venous thromboembolism.

  3. High PDGFB expression is associated with glioma.

  4. A cell-autonomous positive-signaling circuit is associated with the PDGF (show PDGFA Antibodies)-NO-ID4 (show ID4 Antibodies)-regulatory axis in glioblastoma cells.

  5. SphK1 (show SPHK1 Antibodies) is regulated by PDGF (show PDGFA Antibodies)-BB in pulmonary artery smooth muscle cells via the transcription factor Egr-1 (show EGR1 Antibodies), promoting cell proliferation.

  6. PDGF (show PDGFA Antibodies)-BB regulates the proliferation and differentiation of human melanocytes in a differentiation-stage-specific manner.

  7. Low concentration of PDGF (show PDGFA Antibodies)-AB showed synergism with IFN-alpha (show IFNA Antibodies) in IFN-beta (show IFNB1 Antibodies) and -gamma induction.

  8. There are four platelet-derived growth factor (PDGF (show PDGFA Antibodies)) genes (PDGFA (show PDGFA Antibodies), PDGFB, PDGFC (show PDGFC Antibodies) and PDGFD (show PDGFD Antibodies)) that reside on chromosomes 7, 22, 4 and 11.

  9. this study shows that the expression of PDGFB is significantly downregulated in keloid fibroblasts compared to normal human fibroblasts

  10. this study demonstrated that knockdown of SCARA5 (show SCARA5 Antibodies) inhibits PDGFBBinduced HASMC proliferation and migration through suppression of the PDGF (show PDGFA Antibodies) signaling pathway.

Cow (Bovine) Platelet-Derived Growth Factor beta Polypeptide (PDGFB) interaction partners

  1. Study suggest that PDGF-B is induced by hypoxia and protects against apoptosis via the PI3K/Akt (show AKT1 Antibodies)/Stat3 (show STAT3 Antibodies) signaling pathway.

  2. PDGF-B transcription is increased by Nuclear Factor Kappa B

  3. up-regulated by Angiotensin II in retinal pericytes; results suggest that Ang II (show AGT Antibodies)-type 1 receptor interaction could stimulate PDGF-B gene expression in cultured retinal pericytes through intracellular reactive oxygen species generation

  4. PEDF promotes growth of pericytes through autocrine production of PDGFB.

  5. Hypoxia enhances PDGF-B paracrine interactions between glomerular endothelial and mesangial cells.

PDGFB Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Alternative names and synonyms associated with PDGFB

  • platelet-derived growth factor beta polypeptide (PDGFB) antibody
  • platelet derived growth factor, B polypeptide (Pdgfb) antibody
  • platelet-derived growth factor beta polypeptide (Pdgfb) antibody
  • c-sis antibody
  • PDGF-2 antibody
  • PDGF-B antibody
  • PDGF2 antibody
  • SIS antibody
  • SSV antibody

Protein level used designations for PDGFB

platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) , PDGF subunit B , PDGF-2 , c-sis , platelet-derived growth factor B chain , platelet-derived growth factor beta polypeptide , platelet-derived growth factor subunit B , proto-oncogene c-Sis , PDGF, B chain , becaplermin , platelet-derived growth factor 2 , platelet-derived growth factor, beta polypeptide (oncogene SIS) , Platelet-derived growth factor, same as Sis (Simian sarcoma viral oncogene homologue, c-sis) , pdgf protein , platelet derived growth factor, B polypeptide , platelet-derived growth factor B , v-sis platelet-derived growth factor beta polypeptide (simian sarcoma viral oncogene homolog) , platelet-derived growth factor B subunit

GENE ID SPECIES
100228287 Taeniopygia guttata
18591 Mus musculus
5155 Homo sapiens
24628 Rattus norvegicus
100126843 Sus scrofa
442986 Canis lupus familiaris
540106 Bos taurus
100731469 Cavia porcellus
374128 Gallus gallus
443545 Ovis aries
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