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PDE4C Antibodies

(phosphodiesterase 4C, CAMP-Specific (PDE4C))
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011].
PDE4C antibody  (Internal Region) PDE4C antibody  (Internal Region) PDE4C antibody (Internal Region) (ABIN6259147)

PDE4C Reactivity: Human, Mouse, Rat ELISA, ICC, IF, IHC, WB Host: Rabbit Polyclonal unconjugated

PDE4C antibody  (AA 1-99) PDE4C antibody  (AA 1-99) PDE4C antibody (AA 1-99) (ABIN518723)

PDE4C Reactivity: Human IF, ELISA, WB Host: Mouse Monoclonal 4E5 unconjugated

PDE4C antibody  (Center) PDE4C antibody  (Center) PDE4C antibody (Center) (ABIN2856292)

PDE4C Reactivity: Human IHC (p), WB Host: Rabbit Polyclonal unconjugated

PDE4C Antibodies by Reactivity

Find PDE4C Antibodies for a variety of species such as anti-Human PDE4C, anti-Mouse PDE4C, anti-Rat PDE4C. The species listed below are among those available. Click on a link to go to the corresponding products.

PDE4C Antibodies by Application

Find PDE4C Antibodies validated for a specific application such as WB, ELISA, IF, ICC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

PDE4C Antibodies by Host

Find PDE4C Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

PDE4C Antibodies by Binding Specificity

Find PDE4C Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

PDE4C Antibodies by Clonality

Find available monoclonal or polyclonal PDE4C Antibodies. Click on a link to go to the corresponding products.

PDE4C Antibodies by Clone

Find PDE4C Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

PDE4C Antibodies by Conjugate

Find PDE4C Antibodies with a specific conjugate such as Biotin, FITC, APC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular PDE4C Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, ICC, IF, IHC, WB
Validations
  • (3)
Cat. No. ABIN6259147
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF, ELISA, WB
Validations
  • (3)
Cat. No. ABIN518723
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC (p), WB
Validations
  • (2)
Cat. No. ABIN2856292
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (2)
Cat. No. ABIN518724
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN7187730
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN3186360
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN1539353
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IP, WB
Validations
  • (1)
Cat. No. ABIN7296540
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN2789817
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN562148
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application CM, ICC, IF, IP, IHC, ELISA, WB
Validations
  • (9)
Cat. No. ABIN2750931
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB
Validations
Cat. No. ABIN6282668
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application IP, WB
Validations
Cat. No. ABIN5620486
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN1807558
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ICC, WB
Validations
Cat. No. ABIN2886470
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our PDE4C Antibodies

Cheng, Wu, He, Liu, Jia, Di, Ji: "siRNA-mediated silencing of phosphodiesterase 4B expression affects the production of cytokines in endotoxin-stimulated primary cultured microglia." in: Experimental and therapeutic medicine, Vol. 12, Issue 4, pp. 2257-2264, (2017) (PubMed).

Ji, Di, He, Liu, Liu, Li, Zhang: "Intrathecal injection of phosphodiesterase 4B-specific siRNA attenuates neuropathic pain in rats with L5 spinal nerve ligation." in: Molecular medicine reports, Vol. 13, Issue 2, pp. 1914-22, (2016) (PubMed).

Massimi, Cardarelli, Galli, Giardi, Ragusa, Panera, Cinque, Cifone, Biagioni, Giorgi: "Increase of Intracellular Cyclic AMP by PDE4 Inhibitors Affects HepG2 Cell Cycle Progression and Survival." in: Journal of cellular biochemistry, Vol. 118, Issue 6, pp. 1401-1411, (2016) (PubMed).

Petersen, Kristensen, Jeppesen, Grøndahl, Wissing, Macklon, Andersen: "Distribution and function of 3',5'-Cyclic-AMP phosphodiesterases in the human ovary." in: Molecular and cellular endocrinology, Vol. 403, pp. 10-20, (2015) (PubMed).

Yougbaré, Boire, Roy, Lugnier, Rouseau: "NCS 613 exhibits anti-inflammatory effects on PBMCs from lupus patients by inhibiting p38 MAPK and NF-κB signalling pathways while reducing proinflammatory cytokine production." in: Canadian journal of physiology and pharmacology, Vol. 91, Issue 5, pp. 353-61, (2014) (PubMed).

Abusnina, Alhosin, Keravis, Muller, Fuhrmann, Bronner, Lugnier: "Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis." in: Cellular signalling, Vol. 23, Issue 1, pp. 152-60, (2011) (PubMed).

Yougbare, Morin, Senouvo, Sirois, Albadine, Lugnier, Rousseau: "NCS 613, a potent and specific PDE4 inhibitor, displays anti-inflammatory effects on human lung tissues." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 301, Issue 4, pp. L441-50, (2011) (PubMed).

Murray, Patel, Suda, Zhang, Thistlethwaite, Yuan, Insel: "Expression and activity of cAMP phosphodiesterase isoforms in pulmonary artery smooth muscle cells from patients with pulmonary hypertension: role for PDE1." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 292, Issue 1, pp. L294-303, (2007) (PubMed).

Gallagher, Bacon, Odumeru, Gallagher, Fitzpatrick, Regan: "Valproate activates phosphodiesterase-mediated cAMP degradation: relevance to C6 glioma G1 phase progression." in: Neurotoxicology and teratology, Vol. 26, Issue 1, pp. 73-81, (2004) (PubMed).

Aliases for PDE4C Antibodies

phosphodiesterase 4C (PDE4C) Antibodies
phosphodiesterase 4C, cAMP-specific a (pde4ca) Antibodies
phosphodiesterase 4C (pde4c) Antibodies
phosphodiesterase 4C, cAMP specific (Pde4c) Antibodies
phosphodiesterase 4C (Pde4c) Antibodies
dpde1 Antibodies
Dpde1 Antibodies
DPDE1 Antibodies
dunce Antibodies
E130301F19Rik Antibodies
im:7160317 Antibodies
pde4c Antibodies
PDE4C Antibodies
si:dkey-149i17.5 Antibodies
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