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Browse our anti-PDGFBB (PDGFBB) Antibodies

Full name:
anti-Platelet Derived Growth Factor BB Antibodies (PDGFBB)
On are 70 Platelet Derived Growth Factor BB (PDGFBB) Antibodies from 9 different suppliers available. Additionally we are shipping PDGFBB Kits (67) and PDGFBB Proteins (57) and many more products for this protein. A total of 194 PDGFBB products are currently listed.
c-sis, PDGF-2, PDGF2, SIS, SSV
list all antibodies Gene Name GeneID UniProt
PDGFBB 5155 P01127

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Most Popular Reactivities for anti-PDGFBB (PDGFBB) Antibodies

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More Antibodies against PDGFBB Interaction Partners

Human Platelet Derived Growth Factor BB (PDGFBB) interaction partners

  1. A cell-autonomous positive-signaling circuit is associated with the PDGF (show PDGFA Antibodies)-NO-ID4 (show ID4 Antibodies)-regulatory axis in glioblastoma cells.

  2. SphK1 (show SPHK1 Antibodies) is regulated by PDGF (show PDGFA Antibodies)-BB in pulmonary artery smooth muscle cells via the transcription factor Egr-1 (show EGR1 Antibodies), promoting cell proliferation.

  3. PDGF (show PDGFA Antibodies)-BB regulates the proliferation and differentiation of human melanocytes in a differentiation-stage-specific manner.

  4. Low concentration of PDGF (show PDGFA Antibodies)-AB showed synergism with IFN-alpha (show IFNA Antibodies) in IFN-beta (show IFNB1 Antibodies) and -gamma induction.

  5. There are four platelet-derived growth factor (PDGF (show PDGFA Antibodies)) genes (PDGFA (show PDGFA Antibodies), PDGFB (show PDGFB Antibodies), PDGFC (show PDGFC Antibodies) and PDGFD (show PDGFD Antibodies)) that reside on chromosomes 7, 22, 4 and 11.

  6. this study shows that the expression of PDGFB is significantly downregulated in keloid fibroblasts compared to normal human fibroblasts

  7. this study demonstrated that knockdown of SCARA5 (show SCARA5 Antibodies) inhibits PDGFBBinduced HASMC proliferation and migration through suppression of the PDGF (show PDGFA Antibodies) signaling pathway.

  8. The simultaneous action of PDGF-B (show PDGFB Antibodies)/PDGFRbeta and VEGF165b on the same type of receptor may explain the resistance to antiangiogenic therapy, which depends on the degree of modulation of PDGFRbeta phosphorylation.

  9. The expression of angiogenesis markers VEGF-A (show VEGFA Antibodies), VEGFR (show KDR Antibodies), PDGFbetabeta, PDGFR (show PDGFRB Antibodies), CCND1 (show CCND1 Antibodies) and CA9 (show CA9 Antibodies) was assessed by immunohistochemistry and correlated with overall survival and progression-free survival in patients with renal cell carcinoma (show MOK Antibodies) undergoing therapy with Sunitinib, but no correlation was found between expression of angiogenesis markers and clinical outcome.

  10. ore than 65% of cases had PDGF (show PDGFA Antibodies)-BB mRNA amplification, confirming immunohistochemical results. We herein validated PDGF (show PDGFA Antibodies)-BB as a potential therapeutic and prognostic tool of ovarian cancer aggressiveness.

PDGFBB Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Alternative names and synonyms associated with PDGFBB

  • platelet-derived growth factor beta polypeptide (PDGFB) antibody
  • c-sis antibody
  • PDGF-2 antibody
  • PDGF2 antibody
  • SIS antibody
  • SSV antibody

Protein level used designations for PDGFBB

PDGF subunit B , PDGF, B chain , becaplermin , platelet-derived growth factor 2 , platelet-derived growth factor B chain , platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) , platelet-derived growth factor subunit B , platelet-derived growth factor, beta polypeptide (oncogene SIS) , proto-oncogene c-Sis

5155 Homo sapiens
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