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Browse our anti-PDGFBB (PDGFBB) Antibodies

Full name:
anti-Platelet Derived Growth Factor BB Antibodies (PDGFBB)
On www.antibodies-online.com are 49 Platelet Derived Growth Factor BB (PDGFBB) Antibodies from 11 different suppliers available. Additionally we are shipping PDGFBB Kits (72) and PDGFBB Proteins (69) and many more products for this protein. A total of 190 PDGFBB products are currently listed.
Synonyms:
c-sis, PDGF-2, PDGF2, SIS, SSV
list all antibodies Gene Name GeneID UniProt
PDGFBB 5155 P01127
PDGFBB    
PDGFBB    

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More Antibodies against PDGFBB Interaction Partners

Human Platelet Derived Growth Factor BB (PDGFBB) interaction partners

  1. Loss of Nf2 (show NF2 Antibodies) and Cdkn2a (show CDKN2A Antibodies)/b have synergistic effects with PDGF-B (show PDGFB Antibodies) overexpression promoting meningioma malignant transformation.

  2. Human uPAR (show PLAUR Antibodies) activation and its association with beta1-integrin are required for PDGF (show PDGFA Antibodies)-AB-induced migration.

  3. Placental endothelial cell-derived PDGF (show PDGFA Antibodies)-BB recruits human placental multipotent mesenchymal stromal cells involved in vascular development via PDGFR-beta (show PDGFRB Antibodies)/STAT3 (show STAT3 Antibodies) activation

  4. Suggest that PDGF-B (show PDGFB Antibodies) signaling may play a role in endothelial and cardiomyocyte recovery from ischemia reperfusion injury after heart transplantation.

  5. Lessons from SLC20A2, PDGFB, and PDGFRB mutation carriers. Three causative genes have been identified: SLC20A2, PDGFRB and, recently, PDGFB, whose associated phenotype has not yet been extensively studied.

  6. loss-of-function mutations in PDGFB (show PDGFB Antibodies) or PDGFRB (show PDGFRB Antibodies) cause Primary Familial Brain Calcification.

  7. Three factor model revealed significant gene-gene interaction for PDGFB (show PDGFB Antibodies) +286A>G, PDGFB (show PDGFB Antibodies) +1135A>C and HER2 (show ERBB2 Antibodies) Ile165Val SNPs with GBC. Protein-protein interaction showed significant association of PDGFB (show PDGFB Antibodies) and HER2 (show ERBB2 Antibodies) with EGFR (show EGFR Antibodies) receptor signaling pathway.

  8. Regulation of Hyaluronan (HA) Metabolism Mediated by HYBID (Hyaluronan-binding Protein Involved in HA Depolymerization, KIAA1199 (show KIAA1199 Antibodies)) and HA Synthases in Growth Factor-stimulated Fibroblasts.

  9. Electron microscopy structure of PDGFRB (show PDGFRB Antibodies) [a full-length human platelet-derived growth factor receptor (show PDGFRL Antibodies)], in complex with its ligand PDGF-B (show PDGFB Antibodies).

  10. TM expression in corneal epithelium was modulated during the corneal wound healing process, and may be regulated by PDGF (show PDGFA Antibodies)-BB. In addition, rTMD23 has therapeutic potential in corneal injury

PDGFBB Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Alternative names and synonyms associated with PDGFBB

  • platelet-derived growth factor beta polypeptide (PDGFB) antibody
  • c-sis antibody
  • PDGF-2 antibody
  • PDGF2 antibody
  • SIS antibody
  • SSV antibody

Protein level used designations for PDGFBB

PDGF subunit B , PDGF, B chain , becaplermin , platelet-derived growth factor 2 , platelet-derived growth factor B chain , platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) , platelet-derived growth factor subunit B , platelet-derived growth factor, beta polypeptide (oncogene SIS) , proto-oncogene c-Sis

GENE ID SPECIES
5155 Homo sapiens
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