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Browse our anti-PDGFBB (PDGFBB) Antibodies

Full name:
anti-Platelet Derived Growth Factor BB Antibodies (PDGFBB)
On www.antibodies-online.com are 48 Platelet Derived Growth Factor BB (PDGFBB) Antibodies from 10 different suppliers available. Additionally we are shipping PDGFBB Proteins (65) and PDGFBB Kits (57) and many more products for this protein. A total of 170 PDGFBB products are currently listed.
Synonyms:
c-sis, PDGF-2, PDGF2, SIS, SSV
list all antibodies Gene Name GeneID UniProt
PDGFBB 5155 P01127
PDGFBB    
PDGFBB    

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More Antibodies against PDGFBB Interaction Partners

Human Platelet Derived Growth Factor BB (PDGFBB) interaction partners

  1. The simultaneous action of PDGF-B (show PDGFB Antibodies)/PDGFRbeta and VEGF165b on the same type of receptor may explain the resistance to antiangiogenic therapy, which depends on the degree of modulation of PDGFRbeta phosphorylation.

  2. The expression of angiogenesis markers VEGF-A (show VEGFA Antibodies), VEGFR (show KDR Antibodies), PDGFbetabeta, PDGFR (show PDGFRB Antibodies), CCND1 (show CCND1 Antibodies) and CA9 (show CA9 Antibodies) was assessed by immunohistochemistry and correlated with overall survival and progression-free survival in patients with renal cell carcinoma (show MOK Antibodies) undergoing therapy with Sunitinib, but no correlation was found between expression of angiogenesis markers and clinical outcome.

  3. ore than 65% of cases had PDGF (show PDGFA Antibodies)-BB mRNA amplification, confirming immunohistochemical results. We herein validated PDGF (show PDGFA Antibodies)-BB as a potential therapeutic and prognostic tool of ovarian cancer aggressiveness.

  4. Case Report: congenital atrophic dermatofibrosarcoma protuberans with COL1A1-PDGFB rearrangement.

  5. Loss of Nf2 (show NF2 Antibodies) and Cdkn2a (show CDKN2A Antibodies)/b have synergistic effects with PDGF-B (show PDGFB Antibodies) overexpression promoting meningioma malignant transformation.

  6. Human uPAR (show PLAUR Antibodies) activation and its association with beta1-integrin are required for PDGF (show PDGFA Antibodies)-AB-induced migration.

  7. Placental endothelial cell-derived PDGF (show PDGFA Antibodies)-BB recruits human placental multipotent mesenchymal stromal cells involved in vascular development via PDGFR-beta (show PDGFRB Antibodies)/STAT3 (show STAT3 Antibodies) activation

  8. Suggest that PDGF-B (show PDGFB Antibodies) signaling may play a role in endothelial and cardiomyocyte recovery from ischemia reperfusion injury after heart transplantation.

  9. Lessons from SLC20A2, PDGFB, and PDGFRB mutation carriers. Three causative genes have been identified: SLC20A2, PDGFRB and, recently, PDGFB, whose associated phenotype has not yet been extensively studied.

  10. loss-of-function mutations in PDGFB (show PDGFB Antibodies) or PDGFRB (show PDGFRB Antibodies) cause Primary Familial Brain Calcification.

PDGFBB Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Alternative names and synonyms associated with PDGFBB

  • platelet-derived growth factor beta polypeptide (PDGFB) antibody
  • c-sis antibody
  • PDGF-2 antibody
  • PDGF2 antibody
  • SIS antibody
  • SSV antibody

Protein level used designations for PDGFBB

PDGF subunit B , PDGF, B chain , becaplermin , platelet-derived growth factor 2 , platelet-derived growth factor B chain , platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) , platelet-derived growth factor subunit B , platelet-derived growth factor, beta polypeptide (oncogene SIS) , proto-oncogene c-Sis

GENE ID SPECIES
5155 Homo sapiens
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