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Platelet-Derived Growth Factor Receptor, alpha Polypeptide ELISA Kits (PDGFRA)
On are 56 Platelet-Derived Growth Factor Receptor, alpha Polypeptide (PDGFRA) ELISA Kits from 14 different suppliers available. Additionally we are shipping PDGFRA Antibodies (540) and PDGFRA Proteins (32) and many more products for this protein. A total of 657 PDGFRA products are currently listed.
list all ELISA KIts Gene Name GeneID UniProt
PDGFRA 18595 P26618
PDGFRA 25267 P20786
PDGFRA 5156 P16234

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More ELISA Kits for PDGFRA Interaction Partners

Mouse (Murine) Platelet-Derived Growth Factor Receptor, alpha Polypeptide (PDGFRA) interaction partners

  1. PDGFRalpha and PDGFRbeta are coexpressed in the craniofacial mesenchyme of mid-gestation mouse embryos and that ablation of Pdgfrb (show PDGFRB ELISA Kits) in the neural crest lineage results in increased nasal septum width, delayed palatal shelf development, and subepidermal blebbing.

  2. The results from this study indicate that PDGF (show PDGFA ELISA Kits) signaling is required for fiber hypertrophy, extracellular matrix production, and angiogenesis that occur during muscle growth.

  3. transient middle cerebral-arterial occlusion (MCAO) was introduced into the mice with conditional Pdgfrb (show PDGFRB ELISA Kits)-gene inactivation, including N-PRbeta-KO mice where the Pdgfrb (show PDGFRB ELISA Kits)-gene was mostly inactivated in the brain except that in vascular pericytes

  4. PDGFR alpha has an important role in cranial neural crest cell mitosis within the mandibular processes

  5. PDGF (show PDGFA ELISA Kits) signalling in the dermis and in dermal condensates is dispensable for hair follicle induction and formation.

  6. PDGFRalpha has a role in demarcating the cardiogenic clonogenic Sca1 (show ATXN1 ELISA Kits)+ stem/progenitor cell in adult murine myocardium

  7. In KIT-mutant GIST, inhibition of PDGFRA disrupts a KIT-ERK (show EPHB2 ELISA Kits)-ETV1 (show ETV1 ELISA Kits)-KIT signaling loop by inhibiting ERK (show EPHB2 ELISA Kits) activation.

  8. Ganglioside GD3 enhances invasiveness of gliomas by forming a complex with PDGFRalpha and Yes Kinase (show YES1 ELISA Kits).

  9. Primary high invasive Glioma initiating cells SU3 contribute to transformation of adjacent normal host glial cells in local tumor microenvironment possibly via PDGF (show PDGFA ELISA Kits)/PDGFR (show PDGFRB ELISA Kits) signaling activation.

  10. Data indicate that PDGF (show PDGFA ELISA Kits)-AA promotes mesenchymal stem cel migration via bone morphogenetic protein 2 (BMP2 (show BMP2 ELISA Kits))-smad (show SMAD1 ELISA Kits) proteins smad1 (show SMAD1 ELISA Kits)/5/8 activation requires lysosome-mediated degradation of PDGF (show PDGFA ELISA Kits) alpha Receptor (PDGFRalpha).

Human Platelet-Derived Growth Factor Receptor, alpha Polypeptide (PDGFRA) interaction partners

  1. PDGFRa amplification in multiple skin lesions of undifferentiated pleomorphic sarcoma

  2. PDGFRA mutations were associated with gastrointestinal stromal tumors.

  3. The PDGFRA kinase domain structure we report in this study has potential to facilitate development of new agents which can inhibit this kinase, including both its activating and drug-resistant mutations.

  4. BRAF (show BRAF ELISA Kits) mutations are rare events in KIT/PDGFRA wild-type gastrointestinal stromal tumors.

  5. There are two platelet-derived growth factor receptor (PDGFR (show PDGFRB ELISA Kits)) genes (PDGFRA and PDGFRB (show PDGFRB ELISA Kits)), and they reside on chromosome 4 and 5.

  6. Data did not detect any significant association with SNPs of APRIL, SPATA8, PDGFRA, and POLB with Systemic Lupus Erythematosus in Chinese Han Population.

  7. Synchronous T lymphoblastic lymphoma and myeloid neoplasm with PDGFRA rearrangement.

  8. Stromal expression of PDGFRA increased with increasing histologic grade of breast phyllodes tumor. PDGFR (show PDGFRB ELISA Kits) stromal positivity was associated with shorter overall survival.

  9. genome analysis of wild-type gastrointestinal stromal tumors for mutations should include the BRAF (show BRAF ELISA Kits) gene in patients with KIT and PDGFRA wild-type gastrointestinal stromal tumors

  10. We demonstrate in cell lines, SCID (show PRKDC ELISA Kits) xenografts and human tumor specimens that PDGFRalpha promotes dedifferentiation in PTC (show F9 ELISA Kits) by decreasing TTF1 (show NKX2-1 ELISA Kits) expression in the nucleus, which decreases iodide transport and thyroglobulin (show TG ELISA Kits) production in thyroid follicular cells.

PDGFRA Antigen Profile

Antigen Summary

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

Alternative names and synonyms associated with PDGFRA

  • platelet-derived growth factor receptor, alpha polypeptide (PDGFRA) Elisa Kit
  • platelet-derived growth factor receptor, alpha polypeptide (LOC100218386) Elisa Kit
  • platelet derived growth factor receptor, alpha polypeptide (Pdgfra) Elisa Kit
  • platelet derived growth factor receptor, alpha polypeptide (pdgfra) Elisa Kit
  • platelet-derived growth factor receptor alpha (LOC100343006) Elisa Kit
  • AI115593 Elisa Kit
  • APDGFR Elisa Kit
  • CD140A Elisa Kit
  • PDGFACE Elisa Kit
  • PDGFR Elisa Kit
  • PDGFR-2 Elisa Kit
  • PDGFR-A Elisa Kit
  • PDGFR2 Elisa Kit
  • RHEPDGFRA Elisa Kit

Protein level used designations for PDGFRA

platelet-derived growth factor receptor, alpha polypeptide , alpha-type platelet-derived growth factor receptor-like , Alpha platelet-derived growth factor receptor precursor (PDGF-R-alpha) , CD140 antigen-like family member A , PDGF alpha chain , PDGF-R-alpha , PDGFR-alpha , alpha-type platelet-derived growth factor receptor , platelet-derived growth factor alpha receptor , platelet-derived growth factor receptor alpha , alpha platelet-derived growth factor receptor , CD140a antigen , PDGFRA/BCR fusion , platelet-derived growth factor receptor 2 , rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein , tyrosine kinase PDGFR

100059815 Equus caballus
100218386 Taeniopygia guttata
100412331 Callithrix jacchus
100431735 Pongo abelii
100464991 Ailuropoda melanoleuca
18595 Mus musculus
25267 Rattus norvegicus
380245 Xenopus laevis
100343006 Oryctolagus cuniculus
5156 Homo sapiens
442860 Canis lupus familiaris
407607 Sus scrofa
282301 Bos taurus
395509 Gallus gallus
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