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Browse our anti-Phospholipase C gamma 1 (PLCG1) Antibodies

Full name:
anti-phospholipase C, gamma 1 Antibodies (PLCG1)
On are 269 phospholipase C, gamma 1 (PLCG1) Antibodies from 23 different suppliers available. Additionally we are shipping Phospholipase C gamma 1 Kits (38) and Phospholipase C gamma 1 Proteins (6) and many more products for this protein. A total of 323 Phospholipase C gamma 1 products are currently listed.
AI894140, Cded, NCKAP3, Phosphb, PLC'1, Plc-1, Plc-gamma1, PLC-II, PLC1, PLC148, PLCbeta1, Plcg-1, PLCgamma1, PPLCA, RATPHOSPHB
list all antibodies Gene Name GeneID UniProt
PLCG1 24654 P10687
PLCG1 5335 P19174
PLCG1 18803 Q62077

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Most Popular Reactivities for anti-Phospholipase C gamma 1 (PLCG1) Antibodies

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anti-Rat (Rattus) Phospholipase C gamma 1 Antibodies:

anti-Human Phospholipase C gamma 1 Antibodies:

anti-Mouse (Murine) Phospholipase C gamma 1 Antibodies:

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Top referenced anti-Phospholipase C gamma 1 Antibodies

  1. Human Polyclonal Phospholipase C gamma 1 Primary Antibody for IHC (p), WB - ABIN319399 : Grossman: Integration of developmental signals and the initiation of sporulation in B. subtilis. in Cell 1991 (PubMed)
    Show all 5 references for ABIN319399

  2. Chicken Monoclonal Phospholipase C gamma 1 Primary Antibody for IF, IP - ABIN967699 : Dayanir, Meyer, Lashkari, Rahimi: Identification of tyrosine residues in vascular endothelial growth factor receptor-2/FLK-1 involved in activation of phosphatidylinositol 3-kinase and cell proliferation. in The Journal of biological chemistry 2001 (PubMed)
    Show all 5 references for ABIN967699

  3. Human Polyclonal Phospholipase C gamma 1 Primary Antibody for WB - ABIN197318 : DeBell, Stoica, Verí, Di Baldassarre, Miscia, Graham, Rellahan, Ishiai, Kurosaki, Bonvini: Functional independence and interdependence of the Src homology domains of phospholipase C-gamma1 in B-cell receptor signal transduction. in Molecular and cellular biology 1999 (PubMed)
    Show all 4 references for ABIN197318

  4. Human Polyclonal Phospholipase C gamma 1 Primary Antibody for WB - ABIN196792 : Verí, DeBell, Seminario, DiBaldassarre, Reischl, Rawat, Graham, Noviello, Rellahan, Miscia, Wange, Bonvini: Membrane raft-dependent regulation of phospholipase Cgamma-1 activation in T lymphocytes. in Molecular and cellular biology 2001 (PubMed)
    Show all 4 references for ABIN196792

  5. Human Polyclonal Phospholipase C gamma 1 Primary Antibody for IF, WB - ABIN401590 : Mattaj: A binding consensus: RNA-protein interactions in splicing, snRNPs, and sex. in Cell 1989 (PubMed)
    Show all 3 references for ABIN401590

  6. Chicken Monoclonal Phospholipase C gamma 1 Primary Antibody for BI, IP - ABIN967698 : Vossmeyer, Hofmann, Löster, Reutter, Danker: Phospholipase Cgamma binds alpha1beta1 integrin and modulates alpha1beta1 integrin-specific adhesion. in The Journal of biological chemistry 2002 (PubMed)
    Show all 3 references for ABIN967698

  7. Human Polyclonal Phospholipase C gamma 1 Primary Antibody for IF, ELISA - ABIN1532393 : Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: The DNA sequence and comparative analysis of human chromosome 20. ... in Nature 2002 (PubMed)
    Show all 2 references for ABIN1532393

  8. Human Polyclonal Phospholipase C gamma 1 Primary Antibody for IF (p), IHC (p) - ABIN744908 : Diaz-Flores, Goldschmidt, Depeille, Ng, Akutagawa, Krisman, Crone, Burgess, Williams, Houseman, Shokat, Sampath, Bollag, Roose, Braun, Shannon: PLC-? and PI3K link cytokines to ERK activation in hematopoietic cells with normal and oncogenic Kras. in Science signaling 2013 (PubMed)

More Antibodies against Phospholipase C gamma 1 Interaction Partners

Human phospholipase C, gamma 1 (PLCG1) interaction partners

  1. We show that the decrease in PI(4,5)P2 level under non-stimulated conditions inhibits PTEN (show PTEN Antibodies) activity leading to the aberrant activation of the oncoprotein Akt (show AKT1 Antibodies). As well as defining a novel mechanism of Akt (show AKT1 Antibodies) phosphorylation with important therapeutic consequences, we also demonstrate that differential expression levels of FGFR2 (show FGFR2 Antibodies), Plc11 and Grb2 (show GRB2 Antibodies) correlate with patient survival

  2. These results indicate that PP1 (show PPA1 Antibodies) is recruited to the extracellular calcium-dependent E-cadherin (show CDH1 Antibodies)-catenin-PIP5K1a (show PIP5K1A Antibodies) complex in the plasma membrane to activate PIP5K1a (show PIP5K1A Antibodies), which is required for PLC (show HSPG2 Antibodies)-g1 activation leading to keratinocyte differentiation.

  3. FGFR1 (show FGFR1 Antibodies) dimers forms a complex with its effector PLCgamma1.

  4. High PLC gamma1 expression is associated with gastric adenocarcinoma.

  5. Report PLCG1 genetic alterations in angiosarcomas.

  6. expression of PLC-gamma1 and PIKE (show AGAP2 Antibodies) positively correlated with the tumor differentiation of oral squamous cell carcinoma.

  7. In a transgenic mouse model, PLCgamma1 is the dominant signaling effector by which activation of TrkB (show NTRK2 Antibodies) promotes epilepsy.

  8. hsa (show CD24 Antibodies)-miR (show MLXIP Antibodies)-665 and hsa (show CD24 Antibodies)-miR (show MLXIP Antibodies)-95 were downregulated in GSRCC but upregulated in intestinal gastric adenocarcinoma, and the relatively differential expression of the miRNAs negatively controlling their target genes, GLI2 (show GLI2 Antibodies) and PLCG1

  9. Results provide evidence that PTPRB (show PTPRB Antibodies) and PLCG1 mutations are driving events in a subset of secondary angiosarcomas.

  10. PLCgamma1 is part of the molecular mechanism.

Mouse (Murine) phospholipase C, gamma 1 (PLCG1) interaction partners

  1. our studies demonstrate that PLCgamma1 is important for pre-TCR mediated signal transduction and pre-T cell development.

  2. Knock-down of PLC-gamma-1 induced foreign body giant cell formation.PLC-gamma-1-deficiency caused a decrease in RUNX1 (show RUNX1 Antibodies) and subsequent PU.1 upregulation while subsequent rescue of RUNX1 (show RUNX1 Antibodies) in sh-PLC-gamma-1-transfected cells strongly inhibited foreign body giant cell formation.

  3. study shows that PLCgamma1 controls osteoclast numbers via a CSF-1 (show CSF1 Antibodies)-dependent DAG/beta-catenin (show CTNNB1 Antibodies)/cyclinD1 pathway.

  4. this study shows that PLC-gamma1 contributes to protective activity of LAT (show LAT Antibodies) activity in vivo

  5. PLCgamma1 signaling is involved in the formation of neuronal processes for functionally faithful brain development. [review]

  6. FGFR1 (show FGFR1 Antibodies)/2 act in concert to recruit and transphosphorylate phospholipase Cgamma1.

  7. platelet activation through GPVI (show GP6 Antibodies) and alphaIIbbeta3 utilizes PLCgamma2 (show PLCG2 Antibodies) because PLCgamma1 levels are insufficient to support responsiveness, but that PLCgamma1 can restore responsiveness if expressed at levels normally achieved by PLCgamma2 (show PLCG2 Antibodies).

  8. foci are polymerized de novo as a result of the T cell receptor (TCR) proximal tyrosine kinase (show TYRO3 Antibodies) cascade, and facilitate distal signaling events including PLCgamma1 activation and subsequent cytoplasmic calcium ion elevation

  9. The result indicate that LAT (show LAT Antibodies)-PLCg1 interaction is important for controlling IL-6 (show IL6 Antibodies) production by T cells and demonstrate a critical role of IL-6 (show IL6 Antibodies) in the development of the lymphoproliferative syndrome.

  10. low level of LAT (show LAT Antibodies)-PLC-gamma1 interaction was associated with Th2 polarized differentiation, and this may contribute to the etiology of asthma.

Cow (Bovine) phospholipase C, gamma 1 (PLCG1) interaction partners

  1. This study is the first to indicate that PLC gamma 1 is expressed in bovine adrenal chromaffin cells and has the potential to be activated.

  2. Tyrosine775 is identified as a new, functionally important phosphorylation site on PLC gamma 1; phosphorylation of both Y775 and Y783 is required for PLC gamma 1 activation as measured by antigen receptor-induced Ca2 (show CA2 Antibodies)+ flux, NF-AT (show NFATC3 Antibodies) and AP-1 (show JUN Antibodies) activation.

  3. PLC-gamma1 is regulated via a novel autoinhibitory mechanism involving its carboxy-terminal Src (show SRC Antibodies) homology (SH2C) domain.

Phospholipase C gamma 1 (PLCG1) Antigen Profile

Antigen Summary

The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Phospholipase C gamma 1 (PLCG1)

  • phospholipase C, beta 1 (phosphoinositide-specific) (Plcb1) antibody
  • phospholipase C, gamma 1 (plcg1) antibody
  • phospholipase C, gamma 1 (PLCG1) antibody
  • phospholipase C, gamma 1 (Plcg1) antibody
  • phospholipase C, gamma 1 (LOC100349958) antibody
  • AI894140 antibody
  • Cded antibody
  • NCKAP3 antibody
  • Phosphb antibody
  • PLC'1 antibody
  • Plc-1 antibody
  • Plc-gamma1 antibody
  • PLC-II antibody
  • PLC1 antibody
  • PLC148 antibody
  • PLCbeta1 antibody
  • Plcg-1 antibody
  • PLCgamma1 antibody
  • PPLCA antibody
  • RATPHOSPHB antibody

Protein level used designations for PLCG1

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 , 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1 , PLC-154 , PLC-I , PLC-beta-1 , Phospholipase C-beta1 , phosphoinositide phospholipase C , phosphoinositide phospholipase C-beta-1 , phospholipase C-I , phospholipase C-beta-1 , PLC gamma 1 , phospholipase C-gamma-1b , phospholipase C, gamma 1 , 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate , 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 , 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 , 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 , PLC-148 , PLC-gamma-1 , inositoltrisphosphohydrolase , monophosphatidylinositol phosphodiesterase , phosphatidylinositol phospholipase C , phosphoinositidase C , phosphoinositide phospholipase C-gamma-1 , phospholipase C, gamma 1 (formerly subtype 148) , phospholipase C-148 , phospholipase C-II , phospholipase C-gamma-1 , triphosphoinositide phosphodiesterase , cell differentiation and embryonic development , PLC-II

24654 Rattus norvegicus
398359 Xenopus laevis
100633163 Amphimedon queenslandica
5335 Homo sapiens
18803 Mus musculus
25738 Rattus norvegicus
281987 Bos taurus
100716986 Cavia porcellus
100349958 Oryctolagus cuniculus
485874 Canis lupus familiaris
419175 Gallus gallus
101103341 Ovis aries
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