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Browse our anti-Phospholipase C gamma 1 (PLCG1) Antibodies

Full name:
anti-phospholipase C, gamma 1 Antibodies (PLCG1)
On are 222 phospholipase C, gamma 1 (PLCG1) Antibodies from 22 different suppliers available. Additionally we are shipping Phospholipase C gamma 1 Kits (60) and Phospholipase C gamma 1 Proteins (5) and many more products for this protein. A total of 297 Phospholipase C gamma 1 products are currently listed.
AI894140, Cded, NCKAP3, Phosphb, PLC'1, Plc-1, Plc-gamma1, PLC-II, PLC1, PLC148, PLCbeta1, Plcg-1, PLCgamma1, PPLCA, RATPHOSPHB
list all antibodies Gene Name GeneID UniProt
PLCG1 24654 P10687
PLCG1 5335 P19174
PLCG1 18803 Q62077

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Most Popular Reactivities for anti-Phospholipase C gamma 1 (PLCG1) Antibodies

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anti-Rat (Rattus) Phospholipase C gamma 1 Antibodies:

anti-Human Phospholipase C gamma 1 Antibodies:

anti-Mouse (Murine) Phospholipase C gamma 1 Antibodies:

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Top referenced anti-Phospholipase C gamma 1 Antibodies

  1. Chicken Monoclonal Phospholipase C gamma 1 Primary Antibody for IF, IP - ABIN967699 : Dayanir, Meyer, Lashkari, Rahimi: Identification of tyrosine residues in vascular endothelial growth factor receptor-2/FLK-1 involved in activation of phosphatidylinositol 3-kinase and cell proliferation. in The Journal of biological chemistry 2001 (PubMed)
    Show all 5 references for ABIN967699

  2. Human Polyclonal Phospholipase C gamma 1 Primary Antibody for IHC (p), WB - ABIN319399 : Grossman: Integration of developmental signals and the initiation of sporulation in B. subtilis. in Cell 1991 (PubMed)
    Show all 5 references for ABIN319399

  3. Human Polyclonal Phospholipase C gamma 1 Primary Antibody for WB - ABIN197318 : DeBell, Stoica, Verí, Di Baldassarre, Miscia, Graham, Rellahan, Ishiai, Kurosaki, Bonvini: Functional independence and interdependence of the Src homology domains of phospholipase C-gamma1 in B-cell receptor signal transduction. in Molecular and cellular biology 1999 (PubMed)
    Show all 4 references for ABIN197318

  4. Human Polyclonal Phospholipase C gamma 1 Primary Antibody for WB - ABIN196792 : Verí, DeBell, Seminario, DiBaldassarre, Reischl, Rawat, Graham, Noviello, Rellahan, Miscia, Wange, Bonvini: Membrane raft-dependent regulation of phospholipase Cgamma-1 activation in T lymphocytes. in Molecular and cellular biology 2001 (PubMed)
    Show all 4 references for ABIN196792

  5. Human Polyclonal Phospholipase C gamma 1 Primary Antibody for IF, WB - ABIN401590 : Mattaj: A binding consensus: RNA-protein interactions in splicing, snRNPs, and sex. in Cell 1989 (PubMed)
    Show all 3 references for ABIN401590

  6. Chicken Monoclonal Phospholipase C gamma 1 Primary Antibody for BI, IP - ABIN967698 : Vossmeyer, Hofmann, Löster, Reutter, Danker: Phospholipase Cgamma binds alpha1beta1 integrin and modulates alpha1beta1 integrin-specific adhesion. in The Journal of biological chemistry 2002 (PubMed)
    Show all 3 references for ABIN967698

  7. Human Polyclonal Phospholipase C gamma 1 Primary Antibody for IF, ELISA - ABIN1532393 : Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: The DNA sequence and comparative analysis of human chromosome 20. ... in Nature 2002 (PubMed)
    Show all 2 references for ABIN1532393

More Antibodies against Phospholipase C gamma 1 Interaction Partners

Human phospholipase C, gamma 1 (PLCG1) interaction partners

  1. Report PLCG1 genetic alterations in angiosarcomas.

  2. expression of PLC-gamma1 and PIKE (show AGAP2 Antibodies) positively correlated with the tumor differentiation of oral squamous cell carcinoma.

  3. In a transgenic mouse model, PLCgamma1 is the dominant signaling effector by which activation of TrkB (show NTRK2 Antibodies) promotes epilepsy.

  4. hsa (show CD24 Antibodies)-miR (show MLXIP Antibodies)-665 and hsa (show CD24 Antibodies)-miR (show MLXIP Antibodies)-95 were downregulated in GSRCC but upregulated in intestinal gastric adenocarcinoma, and the relatively differential expression of the miRNAs negatively controlling their target genes, GLI2 (show GLI2 Antibodies) and PLCG1

  5. Results provide evidence that PTPRB (show PTPRB Antibodies) and PLCG1 mutations are driving events in a subset of secondary angiosarcomas.

  6. PLCgamma1 is part of the molecular mechanism.

  7. Recurrent presence of the PLCG1 S345F mutation is associated with nodal peripheral T-cell lymphomas.

  8. The degradation of zonula occludens-1 (ZO-1 (show TJP1 Antibodies)), and claudin-2 (show CLDN2 Antibodies) exhibited a great dependence on the activation of the transient receptor potential melastatin (show TRPM1 Antibodies) (TRPM) 2 (show CLU Antibodies) channel, phospholipase Cgamma1 (PLCgamma1) and the protein kinase (show CDK7 Antibodies) Calpha (show PRKACA Antibodies) (PKCalpha (show PKCa Antibodies)) signaling cascade.

  9. Data from structural, genetic, and mechanistic studies on the role of PLCG1 in cell biology suggest that dysfunctional forms of PLCG1 are linked to immune disorders and cancer. [REVIEW]

  10. This SOCS7 knockdown-attributed effect could be due to a precise anti-PLCg-1 role.

Mouse (Murine) phospholipase C, gamma 1 (PLCG1) interaction partners

  1. FGFR1 (show FGFR1 Antibodies)/2 act in concert to recruit and transphosphorylate phospholipase Cgamma1.

  2. platelet activation through GPVI (show GP6 Antibodies) and alphaIIbbeta3 utilizes PLCgamma2 (show PLCG2 Antibodies) because PLCgamma1 levels are insufficient to support responsiveness, but that PLCgamma1 can restore responsiveness if expressed at levels normally achieved by PLCgamma2 (show PLCG2 Antibodies).

  3. foci are polymerized de novo as a result of the T cell receptor (TCR) proximal tyrosine kinase (show TYRO3 Antibodies) cascade, and facilitate distal signaling events including PLCgamma1 activation and subsequent cytoplasmic calcium ion elevation

  4. The result indicate that LAT (show LAT Antibodies)-PLCg1 interaction is important for controlling IL-6 (show IL6 Antibodies) production by T cells and demonstrate a critical role of IL-6 (show IL6 Antibodies) in the development of the lymphoproliferative syndrome.

  5. low level of LAT (show LAT Antibodies)-PLC-gamma1 interaction was associated with Th2 polarized differentiation, and this may contribute to the etiology of asthma.

  6. These results suggest that proteasome-mediated degradation is involved in hypophosphorylated LAT (show LAT Antibodies) and PLCgamma1 in Dow2-induced anergic T cells. The novel CD3 (show CD3E Antibodies)-specific Ab, Dow2, may provide us with a unique tool for inducing immunosuppression

  7. Membrane tethering of PKCdelta (show PKCd Antibodies) leads to increased force exertion on extracellular matrix through PLCgamma1/EGFR (show EGFR Antibodies) signaling.

  8. EAT-2 (show SH2D1B Antibodies) mediates its effects in natural killer cells by linking SLAM (show SLAMF1 Antibodies) family receptors to phospholipase Cgamma, calcium fluxes, and Erk (show EPHB2 Antibodies) kinase.

  9. Data suggest that transmembrane adaptor protein LAT (show LAT Antibodies)-PLCgamma1 (Phospholipase C gamma 1) signaling may function differently in various subsets of gammadelta T cells.

  10. Data indicate that mutation of the residues on and adjacent to the G helix within the Itk (show ITK Antibodies) kinase domain impairs the catalytic efficacy of PLCgamma1 substrate phosphorylation.

Cow (Bovine) phospholipase C, gamma 1 (PLCG1) interaction partners

  1. This study is the first to indicate that PLC gamma 1 is expressed in bovine adrenal chromaffin cells and has the potential to be activated.

  2. Tyrosine775 is identified as a new, functionally important phosphorylation site on PLC gamma 1; phosphorylation of both Y775 and Y783 is required for PLC gamma 1 activation as measured by antigen receptor-induced Ca2 (show CA2 Antibodies)+ flux, NF-AT (show NFATC3 Antibodies) and AP-1 (show JUN Antibodies) activation.

  3. PLC-gamma1 is regulated via a novel autoinhibitory mechanism involving its carboxy-terminal Src (show SRC Antibodies) homology (SH2C) domain.

Phospholipase C gamma 1 (PLCG1) Antigen Profile

Antigen Summary

The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Phospholipase C gamma 1 (PLCG1)

  • phospholipase C, beta 1 (phosphoinositide-specific) (Plcb1) antibody
  • phospholipase C, gamma 1 (plcg1) antibody
  • phospholipase C, gamma 1 (PLCG1) antibody
  • phospholipase C, gamma 1 (Plcg1) antibody
  • phospholipase C, gamma 1 (LOC100349958) antibody
  • AI894140 antibody
  • Cded antibody
  • NCKAP3 antibody
  • Phosphb antibody
  • PLC'1 antibody
  • Plc-1 antibody
  • Plc-gamma1 antibody
  • PLC-II antibody
  • PLC1 antibody
  • PLC148 antibody
  • PLCbeta1 antibody
  • Plcg-1 antibody
  • PLCgamma1 antibody
  • PPLCA antibody
  • RATPHOSPHB antibody

Protein level used designations for PLCG1

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 , 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1 , PLC-154 , PLC-I , PLC-beta-1 , Phospholipase C-beta1 , phosphoinositide phospholipase C , phosphoinositide phospholipase C-beta-1 , phospholipase C-I , phospholipase C-beta-1 , PLC gamma 1 , phospholipase C-gamma-1b , phospholipase C, gamma 1 , 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate , 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 , 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 , 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 , PLC-148 , PLC-gamma-1 , inositoltrisphosphohydrolase , monophosphatidylinositol phosphodiesterase , phosphatidylinositol phospholipase C , phosphoinositidase C , phosphoinositide phospholipase C-gamma-1 , phospholipase C, gamma 1 (formerly subtype 148) , phospholipase C-148 , phospholipase C-II , phospholipase C-gamma-1 , triphosphoinositide phosphodiesterase , cell differentiation and embryonic development , PLC-II

24654 Rattus norvegicus
398359 Xenopus laevis
100633163 Amphimedon queenslandica
5335 Homo sapiens
18803 Mus musculus
25738 Rattus norvegicus
281987 Bos taurus
100716986 Cavia porcellus
100349958 Oryctolagus cuniculus
485874 Canis lupus familiaris
419175 Gallus gallus
101103341 Ovis aries
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