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Phospholipase C gamma 1 antibody (pTyr783)

PLCG1 Reactivity: Human, Mouse, Rat, Monkey WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6256803
  • Target See all Phospholipase C gamma 1 (PLCG1) Antibodies
    Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))
    Binding Specificity
    • 39
    • 28
    • 14
    • 10
    • 7
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr783
    Reactivity
    • 150
    • 136
    • 126
    • 22
    • 9
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Monkey
    Host
    • 159
    • 23
    Rabbit
    Clonality
    • 143
    • 39
    Polyclonal
    Conjugate
    • 85
    • 11
    • 10
    • 10
    • 10
    • 10
    • 9
    • 9
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    This Phospholipase C gamma 1 antibody is un-conjugated
    Application
    • 120
    • 52
    • 38
    • 30
    • 28
    • 27
    • 19
    • 16
    • 14
    • 13
    • 7
    • 4
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    Phospho-PLCG1 (Tyr783) Antibody detects endogenous levels of PLCG1 only when phosphorylated at Tyrosine 783
    Cross-Reactivity
    Human, Monkey, Mouse (Murine), Rat (Rattus)
    Purification
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    Immunogen
    A synthesized peptide derived from human PLCG1 around the phosphorylation site of Tyrosine 783
    Isotype
    IgG
    Top Product
    Discover our top product PLCG1 Primary Antibody
  • Application Notes
    WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C.Stable for 12 months from date of receipt
    Expiry Date
    12 months
  • Target
    Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))
    Alternative Name
    PLCG1 (PLCG1 Products)
    Synonyms
    NCKAP3 antibody, PLC-II antibody, PLC1 antibody, PLC148 antibody, PLCgamma1 antibody, plc1 antibody, nckap3 antibody, plc-ii antibody, plc148 antibody, plcgamma1 antibody, PPLCA antibody, AI894140 antibody, Cded antibody, Plc-1 antibody, Plc-gamma1 antibody, Plcg-1 antibody, fj46f04 antibody, wu:fj46f04 antibody, wu:fj57a05 antibody, phospholipase C gamma 1 antibody, phospholipase C gamma 1 L homeolog antibody, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 antibody, phospholipase C, gamma 1 antibody, PLCG1 antibody, plcg1.L antibody, LOC100633163 antibody, Plcg1 antibody, plcg1 antibody
    Background

    Description: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration.

    Gene: PLCG1

    Molecular Weight
    155kDa
    Gene ID
    5335
    UniProt
    P19174
    Pathways
    RTK Signaling, WNT Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, VEGFR1 Specific Signals, VEGF Signaling
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