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Browse our anti-TEK (TEK) Antibodies

Full name:
anti-TEK Tyrosine Kinase, Endothelial Antibodies (TEK)
On www.antibodies-online.com are 371 TEK Tyrosine Kinase, Endothelial (TEK) Antibodies from 32 different suppliers available. Additionally we are shipping TEK Kits (68) and TEK Proteins (40) and many more products for this protein. A total of 498 TEK products are currently listed.
Synonyms:
AA517024, CD202B, DKFZp469E064, Hyk, TEK, Tie-2, tie2, VMCM, VMCM1
list all antibodies Gene Name GeneID UniProt
TEK 21687  
TEK 7010 Q02763
TEK 89804  

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Most Popular Reactivities for anti-TEK (TEK) Antibodies

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anti-Mouse (Murine) TEK Antibodies:

anti-Human TEK Antibodies:

anti-Rat (Rattus) TEK Antibodies:

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Top referenced anti-TEK Antibodies

  1. Human Polyclonal TEK Primary Antibody for EIA, IHC (p) - ABIN359945 : Cascone, Audero, Giraudo, Napione, Maniero, Philips, Collard, Serini, Bussolino: Tie-2-dependent activation of RhoA and Rac1 participates in endothelial cell motility triggered by angiopoietin-1. in Blood 2003 (PubMed)
    Show all 5 references for ABIN359945

  2. Human Polyclonal TEK Primary Antibody for EIA - ABIN358489 : DeBusk, Chen, Nishishita, Chen, Thomas, Lin: Tie2 receptor tyrosine kinase, a major mediator of tumor necrosis factor alpha-induced angiogenesis in rheumatoid arthritis. in Arthritis and rheumatism 2003 (PubMed)
    Show all 5 references for ABIN358489

  3. Human Monoclonal TEK Primary Antibody for EIA, FACS - ABIN155165 : Harris, Reusch, Barleon, Hang, Dobbs, Marme: Soluble Tie2 and Flt1 extracellular domains in serum of patients with renal cancer and response to antiangiogenic therapy. in Clinical cancer research : an official journal of the American Association for Cancer Research 2001 (PubMed)
    Show all 4 references for ABIN155165

  4. Human Monoclonal TEK Primary Antibody for IHC (fro), WB - ABIN967565 : Dumont, Gradwohl, Fong, Puri, Gertsenstein, Auerbach, Breitman: Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo. in Genes & development 1994 (PubMed)
    Show all 4 references for ABIN967565

  5. Human Monoclonal TEK Primary Antibody for EIA, FACS - ABIN115155 : Chin, Greenman, Reusch, Gardiner, Marme, Monson: Changes in serum soluble VEGFR-1 and Tie-2 receptors in colorectal cancer patients following surgical resections. in Anticancer research 2004 (PubMed)
    Show all 4 references for ABIN115155

  6. Human Monoclonal TEK Primary Antibody for EIA, FACS - ABIN155163 : Scheufler, Drevs, van Velthoven, Reusch, Klisch, Augustin, Zentner, Marme: Implications of vascular endothelial growth factor, sFlt-1, and sTie-2 in plasma, serum and cerebrospinal fluid during cerebral ischemia in man. in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002 (PubMed)
    Show all 3 references for ABIN155163

  7. Human Polyclonal TEK Primary Antibody for IHC, ELISA - ABIN1532488 : Ziegler, Bird, Schneringer, Schooley, Baum: Molecular cloning and characterization of a novel receptor protein tyrosine kinase from human placenta. in Oncogene 1993 (PubMed)
    Show all 2 references for ABIN1532488

  8. Human Polyclonal TEK Primary Antibody for IF, ELISA - ABIN1531402 : Sjöblom, Jones, Wood, Parsons, Lin, Barber, Mandelker, Leary, Ptak, Silliman, Szabo, Buckhaults, Farrell, Meeh, Markowitz, Willis, Dawson, Willson, Gazdar, Hartigan, Wu, Liu, Parmigiani, Park et al.: The consensus coding sequences of human breast and colorectal cancers. ... in Science (New York, N.Y.) 2006 (PubMed)
    Show all 2 references for ABIN1531402

  9. Human Polyclonal TEK Primary Antibody for IF (p), IHC (p) - ABIN674649 : Zhao, Hu, Xiang, Gu, Jin, Hua, Zhang, Liu, Zan, Zhang, Zu, Yang, Shi, Zhu, Xu, Cui, Ye: Intranasal administration of human umbilical cord mesenchymal stem cells-conditioned medium enhances vascular remodeling after stroke. in Brain research 2015 (PubMed)

More Antibodies against TEK Interaction Partners

Mouse (Murine) TEK Tyrosine Kinase, Endothelial (TEK) interaction partners

  1. results implicate common genetic variation at the TIE2 locus as a determinant of vascular leak-related clinical outcomes from common infections, suggesting new tools to identify individuals at unusual risk for deleterious complications of infection

  2. the results suggest that an increased level of TNF-alpha (show TNF Antibodies) together with concomitant upregulation of Tie2/Angiopoietin signaling have critical roles in severe dengue infection.

  3. Data support an interactive model of Tie1 (show TIE1 Antibodies) and Tie2 function, in which dynamically regulated Tie1 (show TIE1 Antibodies) versus Tie2 expression determines the net positive or negative effect of Tie1 (show TIE1 Antibodies) on Tie2 signaling.

  4. These results suggest that Tie2 signaling induces alpha4beta1 integrin activation on bone marrow-mast cell progenitor for adhesion to VCAM-1 (show VCAM1 Antibodies).

  5. Report accelerated lung regeneration by platelet-rich plasma extract through Lrp5 (show LRP5 Antibodies)/Tie2 pathway.

  6. Rapamycin improves TIE2-mutated venous malformation

  7. an EPC (show TCF21 Antibodies) SDF-1 (show CXCL12 Antibodies)/CXCR4 (show CXCR4 Antibodies) axis plays an important role in bone fracture healing using Tie2-Cre(ER) CXCR4 (show CXCR4 Antibodies) conditional knockout mice.

  8. Immunohistological analysis of the tumors showed that Tie2-dependent a6 gene deletion was associated with reduced tumor vascularization and with reduced infiltration of proangiogenic Tie2-expressing macrophages

  9. These results suggest that PRP extract prevents endotoxin-induced pulmonary edema mainly through Ang (show ANG Antibodies)-Tie2 signaling, and PRP extract could be a potential therapeutic strategy for sepsis-induced pulmonary edema

  10. VE-PTP (show PTPRB Antibodies) activates TIE2 and stabilizes retinal and choroidal blood vessels

Human TEK Tyrosine Kinase, Endothelial (TEK) interaction partners

  1. pro-angiogenic Tie-2-expressing monocytes (TEM (show CYLD Antibodies)) and endothelial progenitor cells (EPC (show TCF21 Antibodies)) play a crucial role in Critical limb ischemia.

  2. dysregulation of the angiopoietin (Angpt)/Tie2 ligand (show ANGPT2 Antibodies) receptor system may be crucial for endothelial dysfunction in hemolytic uremic syndrome

  3. we report the analysis of a comprehensive collection of 22 TIE2 mutations identified in patients with vascular morphogenesis

  4. The inhibition of Tie-2 exerted by Tie-1can be relieved by Tie-1 (show TIE1 Antibodies) ectodomain cleavage mediated by tumor- and inflammatory-related factors, which causes destabilization of vessels and initiates vessel remodeling in cancer. (Review)

  5. These results suggest that Tie2 signaling induces alpha4beta1 integrin activation on bone marrow-mast cell progenitor for adhesion to VCAM-1 (show VCAM1 Antibodies).

  6. we show that VEGFA (show VEGFA Antibodies) signaling from TIE2(hi) TMEM macrophages results in local, transient vascular permeability and tumor cell intravasation.

  7. In the absence of Tie-2, VE-PTP (show PTPRB Antibodies) inhibition destabilizes endothelial barrier integrity in agreement with the VE-cadherin (show CDH5 Antibodies)-supportive effect of VE-PTP (show PTPRB Antibodies).

  8. Data indicate that foretinib suppresses angiogenesis and lymphangiogenesis by blocking vascular endothelial growth factor receptors

  9. Genetic variation contributes to the interindividual variation in growth factor levels and explains a modest proportion of circulating hepatocyte growth factor (show HGF Antibodies), Ang-2 (show ANGPT2 Antibodies), and Tie-2.

  10. Data indicate that vascular malformations (VMs) are mediated by mutations in receptor tyrosine kinase (show RET Antibodies) Tie2 (TEK).

Zebrafish TEK Tyrosine Kinase, Endothelial (TEK) interaction partners

  1. observations demonstrate that Tie2 is an important regulator of tip cell behaviors

  2. Tie-1 (show TIE1 Antibodies) and Tie-2 are not required for early heart development, yet they have redundant roles for the maintenance of endocardial-myocardial connection in later stages.

TEK Antigen Profile

Antigen Summary

The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations\; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.

Alternative names and synonyms associated with TEK

  • TEK tyrosine kinase, endothelial (TEK) antibody
  • TEK tyrosine kinase, endothelial (LOC100356675) antibody
  • TEK tyrosine kinase, endothelial (tek) antibody
  • endothelial-specific receptor tyrosine kinase (Tek) antibody
  • TEK tyrosine kinase, endothelial (Tek) antibody
  • AA517024 antibody
  • CD202B antibody
  • DKFZp469E064 antibody
  • Hyk antibody
  • TEK antibody
  • Tie-2 antibody
  • tie2 antibody
  • VMCM antibody
  • VMCM1 antibody

Protein level used designations for TEK

growth factor receptor Tie2/Tek , TEK tyrosine kinase, endothelial (venous malformations, multiple cutaneous and mucosal) , Angiopoietin-1 receptor , TEK tyrosine kinase, endothelial , angiopoietin-1 receptor-like , STK1 , angiopoietin-1 receptor , endothelial tyrosine kinase , mTIE2 , p140 TEK , tunica interna endothelial cell kinase , tyrosine kinase with Ig and EGF homology domains-2 , tyrosine-protein kinase receptor TEK , tyrosine-protein kinase receptor TIE-2 , hTIE2 , soluble TIE2 variant 1 , soluble TIE2 variant 2 , protein-tyrosine kinase Tie2 , endothelial-specific receptor tyrosine kinase , tyrosine kinases that contain immunoglobulin-like loops and epidermal growth factor-similar domains 2 , endothelium-specific receptor tyrosine kinase 2 , tyrosine-protein kinase receptor Tie-2

GENE ID SPECIES
403714 Canis lupus familiaris
465028 Pan troglodytes
707455 Macaca mulatta
100174302 Pongo abelii
100356675 Oryctolagus cuniculus
100408334 Callithrix jacchus
100492432 Xenopus (Silurana) tropicalis
100606897 Nomascus leucogenys
21687 Mus musculus
7010 Homo sapiens
396729 Sus scrofa
89804 Rattus norvegicus
280939 Bos taurus
30747 Danio rerio
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