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TEK antibody (C-Term)

TEK Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB01525-01526 unconjugated
Catalog No. ABIN392059
  • Target See all TEK Antibodies
    TEK (TEK Tyrosine Kinase, Endothelial (TEK))
    Binding Specificity
    • 19
    • 19
    • 16
    • 10
    • 9
    • 8
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 758-789, C-Term
    Reactivity
    • 135
    • 66
    • 49
    • 22
    • 4
    • 3
    Human
    Host
    • 127
    • 17
    • 3
    • 2
    • 2
    Rabbit
    Clonality
    • 133
    • 18
    Polyclonal
    Conjugate
    • 69
    • 10
    • 9
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This TEK antibody is un-conjugated
    Application
    • 79
    • 59
    • 40
    • 40
    • 36
    • 27
    • 14
    • 13
    • 12
    • 8
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    B
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This TEK (TIE2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 758-789 amino acids from the C-terminal region of human TEK (TIE2).
    Clone
    RB01525-01526
    Isotype
    Ig Fraction
    Top Product
    Discover our top product TEK Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    TEK (TEK Tyrosine Kinase, Endothelial (TEK))
    Alternative Name
    TEK (TIE2) (TEK Products)
    Synonyms
    TEK antibody, DKFZp469E064 antibody, AA517024 antibody, Cd202b antibody, Hyk antibody, Tie2 antibody, tie-2 antibody, CD202B antibody, TIE-2 antibody, TIE2 antibody, VMCM antibody, VMCM1 antibody, Tie-2 antibody, tie2 antibody, TEK receptor tyrosine kinase antibody, angiopoietin-1 receptor antibody, TEK tyrosine kinase, endothelial antibody, TEK antibody, LOC100408334 antibody, tek antibody, Tek antibody
    Background
    The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations, the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.
    Molecular Weight
    125830
    Gene ID
    7010
    NCBI Accession
    NP_000450
    UniProt
    Q02763
    Pathways
    RTK Signaling, Growth Factor Binding
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