Browse our anti-VEGFC (VEGFC) Antibodies

Full name:
anti-Vascular Endothelial Growth Factor C Antibodies (VEGFC)
On www.antibodies-online.com are 288 Vascular Endothelial Growth Factor C (VEGFC) Antibodies from 27 different suppliers available. Additionally we are shipping VEGFC Proteins (81) and VEGFC Kits (65) and many more products for this protein. A total of 441 VEGFC products are currently listed.
Synonyms:
AW228853, Flt4-L, VEGF-C, VEGFC, VRP, xvegf-c
list all antibodies Gene Name GeneID UniProt
VEGFC 7424 P49767
VEGFC 22341 P97953
VEGFC 114111 O35757

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Most Popular Reactivities for anti-VEGFC (VEGFC) Antibodies

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anti-Human VEGFC Antibodies:

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Top referenced anti-VEGFC Antibodies

  1. Human Polyclonal VEGFC Primary Antibody for IHC (fro), IHC (p) - ABIN258871 : Zampell, Yan, Avraham, Daluvoy, Weitman, Mehrara: HIF-1α coordinates lymphangiogenesis during wound healing and in response to inflammation. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012 (PubMed)
    Show all 8 references for 258871

  2. Human Polyclonal VEGFC Primary Antibody for EIA, IHC (p) - ABIN357425 : Byeon, Jung, Lee, Lee, Lee, Myung, Yang, Hong, Kim, Min, Kim: Clinicopathological significance of vascular endothelial growth factor-C and cyclooxygenase-2 in esophageal squamous cell carcinoma. in Journal of gastroenterology and hepatology 2004 (PubMed)
    Show all 5 references for 357425

  3. Human Polyclonal VEGFC Primary Antibody for FACS, IHC (p) - ABIN650694 : Yan, Zhu, Yu, Ji, Zhang, Ji, Yan, Chen, Liu, Yin, Lin: Expression of vascular endothelial growth factor C and chemokine receptor CCR7 in gastric carcinoma and their values in predicting lymph node metastasis. in World journal of gastroenterology : WJG 2004 (PubMed)
    Show all 3 references for 650694

  4. Human Monoclonal VEGFC Primary Antibody for ICC, IHC (fro) - ABIN438679 : Moussai, Mitsui, Pettersen, Pierson, Shah, Suárez-Fariñas, Cardinale, Bluth, Krueger, Carucci: The human cutaneous squamous cell carcinoma microenvironment is characterized by increased lymphatic density and enhanced expression of macrophage-derived VEGF-C. in The Journal of investigative dermatology 2010 (PubMed)
    Show all 2 references for 438679

  5. Human Monoclonal VEGFC Primary Antibody for EIA, WB - ABIN360868 : Olofsson, Jeltsch, Eriksson, Alitalo: Current biology of VEGF-B and VEGF-C. in Current opinion in biotechnology 2000 (PubMed)
    Show all 2 references for 360868

  6. Human Polyclonal VEGFC Primary Antibody for EIA, FACS - ABIN955510 : Deguchi, Ichikawa, Soga, Watanabe, Kosuga, Takeshita, Konishi, Morimura, Tsujiura, Komatsu, Shiozaki, Okamoto, Fujiwara, Otsuji: Clinical significance of vascular endothelial growth factors C and D and chemokine receptor CCR7 in gastric cancer. in Anticancer research 2010 (PubMed)
    Show all 2 references for 955510

  7. Human Monoclonal VEGFC Primary Antibody for WB - ABIN659094 : Chen, Xie, Cheng, Diao, Cheng, Liu, Xie, Chen, Zhu: Role of interleukin-17 in lymphangiogenesis in non-small-cell lung cancer: Enhanced production of vascular endothelial growth factor C in non-small-cell lung carcinoma cells. in Cancer science 2010 (PubMed)
    Show all 2 references for 659094

  8. Human Monoclonal VEGFC Primary Antibody for WB - ABIN659093 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 2 references for 659093

More Antibodies against VEGFC Interaction Partners

Zebrafish Vascular Endothelial Growth Factor C (VEGFC) interaction partners

  1. data not only reveal a non-canonical function of Mt2 (show MT2 Antibodies) in angiogenesis, but also propose Mt2 (show MT2 Antibodies) as a novel regulator of vegfc expression.

  2. Vegfc signaling increases mafba (show MAFB Antibodies) expression to control downstream transcription

  3. Vegfc is dispensable for facial lymphatic sprouting but not for the complete development of the facial lymphatic network.

  4. In the embryo, phenotypes driven by increased Vegfc are suppressed in the absence of Ccbe1 (show CCBE1 Antibodies), and Vegfc-driven sprouting is enhanced by local Ccbe1 (show CCBE1 Antibodies) overexpression. Moreover, Vegfc- and Vegfr3 (show FLT4 Antibodies)-dependent Erk (show MAPK1 Antibodies) signaling is impaired in the absence of Ccbe1 (show CCBE1 Antibodies).

  5. Vegfc has an essential role in lymphangiogenesis [review]

  6. The parallel growth of motoneuron axons with the dorsal aorta depends on Vegfc/Vegfr3 (show FLT4 Antibodies) signaling in zebrafish.

  7. Vegfc acts in two distinct modes during development: as a paracrine factor secreted from arteries to guide closely associated lymphatic vasculature and as an autocrine factor to drive migratory persistence during angiogenesis.

  8. Rspo1-Wnt-VegfC-Vegfr3 signaling plays a crucial role as an endothelial-autonomous permissive cue for developmental angiogenesis.

  9. Here, we show that vascular endothelial growth factor C (Vegfc), an angiogenic as well as a lymphangiogenic factor, is unexpectedly involved in this process in zebrafish.

  10. The development of lymphatic vessels in zebrafish embyros depends on Vegfc signaling.

Pig (Porcine) Vascular Endothelial Growth Factor C (VEGFC) interaction partners

  1. VEGF-C and VEGF-C156S genes have roles in the pro-lymphangiogenic growth factor therapy of lymphedema

  2. Transcription of the vascular endothelial growth factor C gene (VEGF-C) and translation of the corresponding protein were significantly up-regulated in swine umbilical vein endothelial cells with classical swine fever virus acute infection.

  3. No difference in bioactivity was detected between porcine relaxin-1 (show RLN1 Antibodies) and recombinant human relaxin-2 (show RLN1 Antibodies) in either mice or rats.

  4. During progressive ischemia, functional and metabolic benefits of intramyocardial VEGF-C gene transfer were apparent. VEGF-C-induced collateral formation occurred at the site of gene transfer

Human Vascular Endothelial Growth Factor C (VEGFC) interaction partners

  1. By treating LECs with VEGF (show VEGFA Antibodies)-C156S and analyzing subsequent changes in gene expression, we identified several 'immediate early (show JUN Antibodies)' transcription factors that showed a rapid transient upregulation VEGFR-3 (show FLT4 Antibodies) stimulation. these results reveal an important and unanticipated role of HOXD10 (show HOXD10 Antibodies) in the regulation of VEGFR-3 (show FLT4 Antibodies) signaling in lymphatic endothelial cells, and in the control of lymphangiogenesis and permeability.

  2. In colon cancer samples, there was a positive correlation between the expression of integrin alpha4 and VEGF-C. Integrin alpha4 and VEGF-C were significantly associated with the clinicopathological parameters (LMVD, Duke's stage, and lymph node metastasis). patients with high integrin alpha4 or VEGF-C expression had significantly shorter overall survival and tumor-free survival time.

  3. High VEGFC expression is associated with angiogenesis and lymphangiogenesis.

  4. Adiponectin (show ADIPOQ Antibodies) promoted VEGF-C expression and secretion in human chondrosarcoma cells.

  5. HuR (show ELAVL1 Antibodies) plays important roles in determining malignant aggressiveness and outcome in prostate cancer (PCa (show FLVCR1 Antibodies)), especially in androgen-independent PCa (show FLVCR1 Antibodies) cells, via the regulation of cell proliferation, migration, and expression of VEGF-A (show VEGFA Antibodies), -C, and COX-2 (show COX2 Antibodies).

  6. Study showed that VEGF-C levels are high in hypervolemic and low in euvolemic (and hypovolemic) chronic kidney disease patients; serum VEGF-C levels were significantly correlated with bioimpedance spectroscopy measurements

  7. Taken together, we suggest that ELK3 (show ELK3 Antibodies) is an upstream regulator of the NF-kappaB (show NFKB1 Antibodies) signaling pathway, the inhibition of which leads to the suppression of peritumoral lymphatic vessel development, possibly due to a low VEGFC expression.

  8. These results indicate that VEGF-C-induced MSC (show MSC Antibodies) osteogenesis is mediated through VEGFR2 (show KDR Antibodies) and VEGFR3 (show FLT4 Antibodies), and followed the activation of the ERK (show EPHB2 Antibodies)/RUNX2 (show RUNX2 Antibodies) signaling pathway.

  9. Overexpression of vascular endothelial growth factor C (VEGF-C) in Kazakh esophageal squamous cell carcinoma (ESCC) was significantly associated with gender, depth of tumor invasion, lymph node metastasis and tumor clinical stage.

  10. This paper quantifies the lymphatic microvessel density (LMD) in benign and malignant salivary gland tumors and analyzes the relationship between LMD and tumor expression of vascular endothelial growth factors C (VEGF-C) and the proliferative index.

Mouse (Murine) Vascular Endothelial Growth Factor C (VEGFC) interaction partners

  1. These results reveal an unexpected role for VEGF-C, a major lymphangiogenic growth factor, in the transition to fetal liver erythropoiesis.

  2. Results suggest that interleukin-6 (IL-6 (show IL6 Antibodies)) increases VEGF-C induction and lymphangiogenesis may involve, at least in part, Src (show SRC Antibodies)-FAK (show PTK2 Antibodies)-STAT3 (show STAT3 Antibodies) cascade in lymphatic endothelial cells (LECs).

  3. Data show that heparanase-1 (HPA-1 (show HPSE Antibodies)) induced shedding of heparan sulfate chain from syndecan-1 (SDC-1 (show SDC1 Antibodies)) facilitated the release of vascular endothelial growth factor C (VEGF-C) from SDC-1 (show SDC1 Antibodies)/VEGF-C complex into the medium of hepatocarcinoma cell.

  4. Data show that in the MCF-7 breast cancer cell line, only MT1X (show MT1X Antibodies) metallothioneins (MTs (show NEU2 Antibodies)) positively correlated with vascular endothelial growth factor C (VEGFC).

  5. The findings in this study strongly suggest the following: i) that VEGF-C promotes the proliferative activity and migratory ability of mesenchymal stem cell ; and ii) VEGF-C and Tgfb (show TGFB1 Antibodies) reciprocally regulate mesenchymal stem cell commitment to differentiation into lymphatic endothelial or osteoblastic phenotypes, respectively.

  6. The authors show that VEGF-C is necessary for perinatal lymphangiogenesis, but required for adult lymphatic vessel maintenance only in the intestine.

  7. MT1-MMP (show MMP14 Antibodies) directly cleaves LYVE-1 (show LYVE1 Antibodies) on lymphatic endothelial cells to inhibit LYVE-1 (show LYVE1 Antibodies)-mediated lymphangiogenic responses and restrains the production of VEGF-C.

  8. HA increases lymphangiogenesis in renal fibrosis model and also stimulates vascular endothelial cell growth factor (show FGF1 Antibodies)-C production from macrophages through Toll-like receptor 4 (show TLR4 Antibodies)-dependent signal pathway

  9. Results showed that the VEGF-C/VEGFR-3 (show FLT4 Antibodies) system underlies the protective effect of ischemic preconditioning against forebrain ischemia in the mouse hippocampus

  10. Vascular endothelial growth factor C/VEGFR-3 (show FLT4 Antibodies) signaling modifies HS and CCL21 (show CCL21 Antibodies) gradients around lymphatics, regulating lymphocyte migration.

VEGFC Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.

Alternative names and synonyms associated with VEGFC

  • vascular endothelial growth factor c (vegfc) antibody
  • vascular endothelial growth factor C (VEGFC) antibody
  • vascular endothelial growth factor C (vegfc) antibody
  • vascular endothelial growth factor C (Vegfc) antibody
  • vascular endothelial growth factor C-like (LOC100525960) antibody
  • AW228853 antibody
  • Flt4-L antibody
  • VEGF-C antibody
  • VEGFC antibody
  • VRP antibody
  • xvegf-c antibody

Protein level used designations for VEGFC

vascular endothelial growth factor C , vascular endothelial growth factor c , FLT4 ligand DHM , VEGF-C , vascular endothelial growth factor-related protein , VRP , flt4 ligand , flt4-L , vascular endothelial growth factor C isoform 129 , vascular endothelial growth factor C isoform 184

GENE ID SPECIES
403049 Danio rerio
699502 Macaca mulatta
100380462 Salmo salar
734331 Xenopus laevis
100127470 Sus scrofa
7424 Homo sapiens
22341 Mus musculus
114111 Rattus norvegicus
100338211 Oryctolagus cuniculus
100724469 Cavia porcellus
282122 Bos taurus
482932 Canis lupus familiaris
422573 Gallus gallus
101105629 Ovis aries
100525960 Sus scrofa
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