VEGFC antibody

Catalog No. ABIN4915116

The Mouse Monoclonal anti-VEGFC antibody (Clone 7C4) (ABIN4915116) specifically detects VEGFC in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for VEGFC antibody (ABIN4915116)

Target: VEGFC (Vascular Endothelial Growth Factor C (VEGFC))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This VEGFC antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 7C4

Product Details anti-VEGFC Antibody

Purpose: VEGF-C (7C4) Monoclonal Antibody

Predicted Reactivity: Human,Mouse,Rat

Purification: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This VEGFC monoclonal antibody is generated from mouse immunized with VEGFC recombinant protein.

Isotype: IgG1

Application Details

Application Notes: WB(1:300-5000)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin, Sodium azide

Precaution of Use: This product contains ProClin and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for VEGFC

Target: VEGFC (Vascular Endothelial Growth Factor C (VEGFC))

Alternative Name: VEGFC

Background:

Synonyms: VRP, Flt4-L, LMPH1D, Vascular endothelial growth factor C, VEGF-C, Flt4 ligand, Vascular endothelial growth factor-related protein, VEGFC

Background: Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.

Gene ID: 7424

UniProt: P49767

Pathways: RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2