Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species and application
anti-Mouse (Murine) Filaggrin Antibodies:
anti-Human Filaggrin Antibodies:
anti-Rat (Rattus) Filaggrin Antibodies:
Go to our pre-filtered search.
Human Monoclonal Filaggrin Primary Antibody for FACS, IF - ABIN5578197
Gan, McBride, Idler, Markova, Steinert: Organization, structure, and polymorphisms of the human profilaggrin gene. in Biochemistry 1991
CDC42 (show CDC42 Antibodies) is involved in the trafficking of FGF receptors to the cell membrane to regulate epicardium formation.
MAPK (show MAPK1 Antibodies) cascades participate in osteogenesis, but only the ERK (show EPHB2 Antibodies) signaling pathway responds to FGFR1 (show FGFR1 Antibodies).
It is well accepted that myelin is a biologically active membrane in active communication with the axons. However, the axonal signals, the receptors on myelin, and the integration of intracellular signaling pathways emanating downstream from these receptors that drive the growth of the myelin sheath remain poorly understood in the CNS. This study brings up the intriguing possibility that FGF receptor (show FGFR2 Antibodies) 2, in the oligodendr
data suggest that FGF2 (show FGF2 Antibodies) levels are critically related to anxiety behavior and hypothalamic pituitary- adrenal axis activity, likely through modulation of hippocampal glucocorticoid receptor (show NR3C1 Antibodies) expression, an effect that is likely receptor mediated, albeit not by FGFR1 (show FGFR1 Antibodies), FGFR2 (show FGFR2 Antibodies), and FGFR3 (show FGFR3 Antibodies).
increased activity of the PI3K/AKT (show AKT1 Antibodies) signaling pathway in Pelo (show PELO Antibodies)-deficient skin might conflict with the dephosphorylation of profilaggrin and thereby affect its proper processing into filaggrin monomers and ultimately the epidermal differentiation
clearly demonstrate the different specificity of FGF12 (show FGF12 Antibodies)-FGFR1c2 and FGF22 (show FGF22 Antibodies)-FGFR1c2 for well defined HS structures and suggest that it is now possible to chemoenzymatically synthesize precise HS polysaccharides that can selectively mediate growth factor signaling
The study supports a pro-adipogenic role for betaKlotho (show KLB Antibodies) in skeletal muscle fibro/adipogenesis and calls for further research on involvement of the FGF-FGFR (show FGFR2 Antibodies)-betaKlotho (show KLB Antibodies) axis in the fibro/adipogenic infiltration associated with functional deterioration of skeletal muscle in aging and muscular dystrophy.
These new findings reveal that the FGF21-betaKlotho-FGFR1 signaling axis plays roles in maintaining phospholipid homeostasis and the dynamic functions of the lipid droplet, whereas protecting against ER stress, and suggest a potential link of phospholipid biosynthesis, lipid droplet dynamics, ER stress, and energy homeostasis in adipose tissue coordinated by this signaling axis.
Data suggest that Fgf1 (show FGF1 Antibodies)-mediated signaling represents an important signaling cascade related to adipogenesis and visceral adiposity; expression of Fgf1 (fibroblast growth factor 1 (show FGF1 Antibodies)) and Fgfr1 (fibroblast growth factor receptor 1 (show FGFR1 Antibodies)) is up-regulated in adipose tissue of obese mice (both obese mice due to high-fat diet and obese mice due to genetic deletion of leptin (show LEP Antibodies)).
FGFR1OP2 (show FGFR1OP2 Antibodies)-FGFR1 (show FGFR1 Antibodies) fusion in hematopoietic stem cells induced myeloid leukemia (show BCL11A Antibodies) and T-cell lymphoma in a mouse model.
FLG (show FGFR1 Antibodies) mutations are risk factors for atopic dermatitis in Finns, but disease severity and treatment response were independent of patient FLG (show FGFR1 Antibodies) status.
Patients with both atopic dermatitis and common filaggrin gene mutations are more frequently affected by reduced health-related quality of life
Multiple lines of evidence suggest that FLG (show FGFR1 Antibodies) genetic variation, have little or no effect on fitness in modern humans. Haplotype-level analysis revealed a recent selective sweep which increased the allele frequency of the Huxian haplogroup in Asian populations.
FLG (show FGFR1 Antibodies) mutations lead to alterations in epidermal eicosanoid metabolism in atopic dermatitis patients
Filaggrin gene mutations are risk factors for the presence and persistence of atopic dermatitis and explain the discordance of atopic dermatitis within dizygotic twin pairs.
Variations in FLG (show FGFR1 Antibodies) and TSLP (show TSLP Antibodies) genotype were associated with differences in self-reported skin clearance, TCI (show LXN Antibodies) usage, and steroid usage.
We show that subjects with FLG (show FGFR1 Antibodies)-null mutations have more mature Langerhans cells in nonlesional skin irrespective of whether they have AD.
we have proposed that this latitude-dependent gradient of FLG (show FGFR1 Antibodies) mutations across Europe, Asia and Africa could have provided an evolutionary advantage for heterozygous FLG (show FGFR1 Antibodies) mutation carriers, residing at northern latitudes, depletion of the FLG (show FGFR1 Antibodies) downstream product, trans-urocanic acid, would facilitate the intracutaneous synthesis of vitamin D3 by allowing increased transcutaneous absorption of UVB photons
The results of the present study demonstrate that filaggrin knockdown inhibits NHEK migration, adhesion and proliferation, promotes apoptosis and disturbs cell cycle progression.
FLG (show FGFR1 Antibodies) rs2065955 polymorphism was significantly related to gastric carcinoma.
The protein encoded by this gene is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Mutations in this gene are associated with ichthyosis vulgaris.
, basic fibroblast growth factor receptor 1
, proto-oncogene c-Fgr
, epidermal filaggrin
, Filaggrin (profilaggrin)
, keratin intermediate filament-associated protein