Browse our anti-DOK7 (DOK7) Antibodies

Full name:
anti-Docking Protein 7 Antibodies (DOK7)
On are 79 Docking Protein 7 (DOK7) Antibodies from 18 different suppliers available. Additionally we are shipping DOK7 Proteins (4) and DOK7 Kits (1) and many more products for this protein. A total of 89 DOK7 products are currently listed.
A930013K19Rik, AW049091, C4orf25, CMS1B, dok-7, EF-12, Oit5, RGD1566416, si:ch211-164d19.2, si:dkey-180b4.3
list all antibodies Gene Name GeneID UniProt
DOK7 285489 Q18PE1
DOK7 231134 Q18PE0
DOK7 305448  

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anti-Human DOK7 Antibodies:

anti-Mouse (Murine) DOK7 Antibodies:

anti-Rat (Rattus) DOK7 Antibodies:

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Top referenced anti-DOK7 Antibodies

  1. Mouse (Murine) Polyclonal DOK7 Primary Antibody for WB - ABIN657491 : Bergamin, Hallock, Burden, Hubbard: The cytoplasmic adaptor protein Dok7 activates the receptor tyrosine kinase MuSK via dimerization. in Molecular cell 2010 (PubMed)
    Show all 2 references for 657491

  2. Human Polyclonal DOK7 Primary Antibody for IF, IHC - ABIN1533938 : Beeson, Higuchi, Palace, Cossins, Spearman, Maxwell, Newsom-Davis, Burke, Fawcett, Motomura, Müller, Lochmüller, Slater, Vincent, Yamanashi: Dok-7 mutations underlie a neuromuscular junction synaptopathy. in Science (New York, N.Y.) 2006 (PubMed)
    Show all 2 references for 1533938

More Antibodies against DOK7 Interaction Partners

Zebrafish Docking Protein 7 (DOK7) interaction partners

  1. Dok-7 promotes slow muscle integrity as well as neuromuscular junction formation in a zebrafish model of congenital myasthenic syndromes.

Human Docking Protein 7 (DOK7) interaction partners

  1. DOK7 was reduced in lung cancer and reduced DOK7 expression was associated with poorer survival.DOK7 isoform 1 plays an inhibitory role on the proliferation and migration of lung cancer cells.

  2. Individuals with DOK7 congenital myasthenic syndrome displayed stridor and feeding difficulties at birth or progressive weakness despite normal milestones in infancy pointing to a diagnosis and should lead to neurophysiological and genetic investigation

  3. this study demonistrated that Salbutamol is an effective treatment in patient wity congenital myasthenic syndrome due to DOK7 mutation.

  4. DOK7 limb-girdle myasthenic syndrome can mimick congenital muscular dystrophy.

  5. Hypermethylation of DOK7 occurs years before tumor diagnosis, suggesting a role as a powerful epigenetic blood-based biomarker as well as providing insights into breast cancer pathogenesis

  6. In contrast to AChR deficiency due to epsilon subunit (show CHRNE Antibodies) mutations, onset of DOK7 CMS (show Cd2ap Antibodies) tends to be later--ages two to three years--and in DOK7 CMS (show Cd2ap Antibodies) eye movements are usually spared and anticholinesterases can exacerbate the weakness

  7. The DOK7 gene is highly polymorphic, and within these many variants, a spectrum of mutations that can underlie DOK7 Congenital myasthenic syndromes that will inform in managing this disorder, were defined.

  8. Sequencing of DOK-7 in seronegative myasthenia gravis patients reveals no mutations.

  9. 6 CMS (show Cd2ap Antibodies) patients with DOK7 mutations had congenital stridor, bilateral vocal cord palsy and difficulty with feeding

  10. This study demonistreated that DOK7 mutation casused congenital myasthenic syndrome in French Canadians.

Mouse (Murine) Docking Protein 7 (DOK7) interaction partners

  1. The Dok-7's C-terminal region plays a key, but not fully essential, role in MuSK (show MUSK Antibodies) activation and NMJ formation.

  2. These results demonstrate that correct, physiological levels of dok-7 expression are required for the postnatal maintenance of neuromuscular junctions.

  3. Protein kinase CK2 (show CSNK2A1 Antibodies) interacts at the neuromuscular synapse with Rapsyn (show RAPSN Antibodies), Rac1, 14-3-3gamma (show YWHAG Antibodies), and Dok-7 proteins and phosphorylates the latter two.

  4. Sp1 (show SP1 Antibodies) plays a crucial role in the regulation of the dok-7 gene.

  5. Data show a critical role for Crk (show CRK Antibodies) and Crk (show CRK Antibodies)-L downstream from Dok-7 in presynaptic and postsynaptic differentiation.

  6. The crystal structure of the Dok7 PH-PTB (show PTBP1 Antibodies) domains in complex with a phosphopeptide representing the Dok7-binding site on MuSK (show MUSK Antibodies), is presented.

  7. Dok-7 is essential for neuromuscular synaptogenesis through its interaction with MuSK (show MUSK Antibodies)

  8. the COOH-terminal NES (show NES Antibodies) and Src (show SRC Antibodies) homology 2 target motifs play key roles in Dok-7/MuSK (show MUSK Antibodies) signaling for neuromuscular synaptogenesis.

DOK7 Antigen Profile

Antigen Summary

The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with DOK7

  • docking protein 7 (DOK7) antibody
  • docking protein 7 (dok7) antibody
  • docking protein 7 (Dok7) antibody
  • downstream of tyrosine kinase 7 (dok7) antibody
  • A930013K19Rik antibody
  • AW049091 antibody
  • C4orf25 antibody
  • CMS1B antibody
  • dok-7 antibody
  • EF-12 antibody
  • Oit5 antibody
  • RGD1566416 antibody
  • si:ch211-164d19.2 antibody
  • si:dkey-180b4.3 antibody

Protein level used designations for DOK7

docking protein 7 , downstream of tyrosine kinase 7 , protein Dok-7 , oncoprotein induced transcript 5

422875 Gallus gallus
488794 Canis lupus familiaris
524590 Bos taurus
557881 Danio rerio
750536 Pan troglodytes
285489 Homo sapiens
231134 Mus musculus
305448 Rattus norvegicus
724073 Takifugu rubripes
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