DOK7 antibody (C-Term)

Catalog No. ABIN926796

Product Details anti-DOK7 Antibody

Target: DOK7 (Docking Protein 7 (DOK7))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOK7 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: DOK7 antibody was raised in rabbit using the C terminal of DOK7 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

DOK7 Blocking Peptide, catalog no. 33R-7809, is also available for use as a blocking control in assays to test for specificity of this DOK7 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for DOK7

Target: DOK7 (Docking Protein 7 (DOK7))

Alternative Name: DOK7 (DOK7 Products)

Synonyms: si:dkey-180b4.3 antibody, si:ch211-164d19.2 antibody, C4orf25 antibody, CMS1B antibody, A930013K19Rik antibody, AW049091 antibody, Dok-7 antibody, EF-12 antibody, Oit5 antibody, RGD1566416 antibody, dok-7 antibody, docking protein 7 antibody, DOK7 antibody, dok7 antibody, Dok7 antibody

Background: The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Synonyms: Polyclonal DOK7 antibody, Anti-DOK7 antibody, docking protein 7 antibody, C4orf25 antibody, CMS1B antibody, FLJ33718 antibody, FLJ39137 antibody, FLJ90556 antibody.

Pathways: Skeletal Muscle Fiber Development