DOK7 antibody (AA 10-59)

Catalog No. ABIN1533938

The Rabbit Polyclonal anti-DOK7 antibody (ABIN1533938) specifically detects DOK7 in WB, IHC, ELISA and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for DOK7 antibody (AA 10-59) (ABIN1533938)

Target: DOK7 (Docking Protein 7 (DOK7))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOK7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-DOK7 Antibody

Binding Specificity: AA 10-59

Purpose: Dok-7 Antibody

Specificity: Dok-7 Polyclonal Antibody detects endogenous levels of Dok-7 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human DOK7. AA range:10-59

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for DOK7

Target: DOK7 (Docking Protein 7 (DOK7))

Alternative Name: DOK7

Background:

Synonyms: DOK7, C4orf25, Protein Dok-7, Downstream of tyrosine kinase 7

Background: docking protein 7(DOK7) Homo sapiens The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009],

Gene Name: DOK7

Protein Name: Protein Dok-7

Molecular Weight: 53 kDa

Gene ID: 285489

OMIM: 254300

UniProt: Q18PE1

Pathways: Skeletal Muscle Fiber Development