Browse our Nucleoporin 98kDa (NUP98) ELISA Kits

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Nucleoporin 98kDa ELISA Kits (NUP98)
On are 18 Nucleoporin 98kDa (NUP98) ELISA Kits from 2 different suppliers available. Additionally we are shipping Nucleoporin 98kDa Antibodies (66) and Nucleoporin 98kDa Proteins (10) and many more products for this protein. A total of 101 Nucleoporin 98kDa products are currently listed.
4732457F17, ADIR2, AI849286, CG10198, CG10201, Dmel\\CG10198, GB12688, im:7151238, l(3)95BCd, Nup-98, Nup 96, NUP96, NUP98, Nup 98, nup98-96, Nup98-Nup96, Nup98/96, nup145, NUP196, zgc:63593, zgc:113968
list all ELISA KIts Gene Name GeneID UniProt
NUP98 269966  
NUP98 81738 P49793
NUP98 4928 P52948

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More ELISA Kits for Nucleoporin 98kDa Interaction Partners

Fruit Fly (Drosophila melanogaster) Nucleoporin 98kDa (NUP98) interaction partners

  1. Nup98 provides a scaffold for poised genes and mediates Induced enhancer-promoter contacts in genetic transcription.

  2. Nup98 associates and colocalizes with the MBD (show DPEP1 ELISA Kits)-R2/NSL and Trx (show GSR ELISA Kits) complexes. Nup98 regulates transcription of Trx (show GSR ELISA Kits) targets, the Hox (show MSH2 ELISA Kits) genes.

  3. Nup98, a virus-induced gene, was antiviral against a panel of viruses.

  4. Study analyzed genomic interactions of full-length nucleoporins Nup98, Nup50 (show NUP50 ELISA Kits), and Nup62 and found that they predominantly interacted with active genes inside the nucleoplasm, particularly those involved in developmental regulation and the cell cycle.

  5. Nup88 (show NUP88 ELISA Kits) localizes to silent loci, Sec13 (show SEC13 ELISA Kits), Nup98, and a subset of FG-repeat nucleoporins bind to developmentally regulated genes undergoing transcription induction.

Mouse (Murine) Nucleoporin 98kDa (NUP98) interaction partners

  1. We demonstrated that Nup98-TopIIbeta and Nup98-SETBP1 (show SETBP1 ELISA Kits) negatively regulate the XPO1 (show XPO1 ELISA Kits)-mediated protein export. Our results will contribute to the understanding of the molecular mechanism by which the Nup98-fusion proteins induce tumorigenesis.

  2. The age-associated accumulation of somatic mutations that occurs in the Nup98-HOXD13 (show HOXD13 ELISA Kits) (NHD13) mouse model of leukemia progression was significantly elevated by co-expression of a PKR (show EIF2AK2 ELISA Kits) transgene.

  3. Nup50 (show NUP50 ELISA Kits) dynamics are independent of importin alpha, Nup153 (show NUP153 ELISA Kits), and Nup98, even though the latter two proteins also exhibit transcription-dependent mobility.

  4. Data indicate that loss of cyclin-dependent kinase inhibitor p15 (p15Ink4b (show CDKN2B ELISA Kits)) collaborates with oncogene (show RAB1A ELISA Kits) fusion protein Nup98-HoxD13 (show HOXD13 ELISA Kits) transgene in the development of predominantly myeloid neoplasms.

  5. Homeobox (show PRRX1 ELISA Kits) partners create more potent NUP98 fusion oncogenes than do non-homeobox (show PRRX1 ELISA Kits) partners.

  6. findings show that expression of NUP98-HOXD13 (show HOXD13 ELISA Kits) impairs class switch recombination and reduces the antibody-mediated immune response, in addition to its role in leukemia

  7. Mice expressing both the FLT3 (show FLT3 ELISA Kits)/ITD and Nup98-HoxD13 (show HOXD13 ELISA Kits) (NHD13) fusion gene developed acute myeloid leukemia (show BCL11A ELISA Kits) with 100% penetrance

  8. Data show that NUP98-HOXA10HD, a novel, canonical NUP98-Hox (show MSH2 ELISA Kits) fusion, significantly enhances the self-renewal capacity of hematopoietic stem cells.

  9. These results clearly demonstrate that Nup98 functions as a novel shuttling cofactor for Crm1 (show XPO1 ELISA Kits)-mediated nuclear export in conjunction with RanBP3 (show RANBP3 ELISA Kits).

  10. A mouse model of CML blast crisis induced by cooperation between BCR/ABL (show ABL1 ELISA Kits) and NUP98/HOXA9 (show HOXA9 ELISA Kits)

Zebrafish Nucleoporin 98kDa (NUP98) interaction partners

  1. data show that a novel nup98 was identified and it serves a role in nucleocytoplasmic trafficking similar to human NUP98.

Human Nucleoporin 98kDa (NUP98) interaction partners

  1. DYNLT1 (show DYNLT1 ELISA Kits) interacts with nucleoporins and plays a role in the dysregulation of gene expression and induction of hematopoietic cell proliferation by the leukemogenic nucleoporin (show AGFG2 ELISA Kits) fusion, NUP98-HOXA9 (show HOXA9 ELISA Kits)

  2. the mutation order in the NUP98-rearranged pediatric AML (show RUNX1 ELISA Kits) begins with the NUP98 rearrangement leading to epigenetic dysregulations then followed by mutations of critical hematopoietic transcription factors and finally, activation of the FLT3 (show FLT3 ELISA Kits) signaling pathway.

  3. These results provide novel insight into the mechanisms underlying the aberrant capability of NUP98 oncoproteins to interact with APC (show APC ELISA Kits)/C(Cdc20 (show CDC20 ELISA Kits)) and to interfere with its function.

  4. Our results suggest that NA10HD increases the number of gamma-globin-transduced HSCs that engraft, leading to an elevated number of fetal hemoglobin-containing red cells.

  5. NUP98-HOXA9 (show HOXA9 ELISA Kits) ability to induce blood cell expansion is evolutionarily conserved.

  6. The study demonstrated the association of NUP98-IQCG with CRM1 (show XPO1 ELISA Kits), and found that NUP98-IQCG expression inhibits the CRM1 (show XPO1 ELISA Kits)-mediated nuclear export of p65 (show GORASP1 ELISA Kits) and enhances the transcriptional activity of nuclear factor-kappaB. Moreover, IQCG could be entrapped in the nucleus by NUP98-IQCG, and the fusion protein interacts with calmodulin (show CALM1 ELISA Kits) via the IQ motif in a calcium-independent manner.

  7. The results indicate that highly selective targeting of Nup98-fusion proteins to Hox (show MSH2 ELISA Kits) cluster regions via prebound Crm1 (show XPO1 ELISA Kits) induces the formation of higher order chromatin structures that causes aberrant Hox (show MSH2 ELISA Kits) gene regulation.

  8. Despite the difference in localization, all tested Nup98 chimera provoked morphological alterations in the nuclear envelope (NE), in particular affecting the nuclear lamina and the lamina-associated polypeptide 2alpha.

  9. NUP98-HOXA9 (show HOXA9 ELISA Kits) expression induces myeloid disease.

  10. Overall, these results demonstrate a novel role for FOXK1 (show FOXK2 ELISA Kits) in regulating the expression of antiviral genes via Nup98, from insects to humans.

Xenopus laevis Nucleoporin 98kDa (NUP98) interaction partners

  1. These data support a model in which Nup98 interacts with microtubules and antagonizes MCAK (show KIF2C ELISA Kits) activity, thus promoting bipolar spindle assembly.

Nucleoporin 98kDa (NUP98) Antigen Profile

Antigen Summary

Signal-mediated nuclear import and export proceed through the nuclear pore complex (NPC), which is comprised of approximately 50 unique proteins collectively known as nucleoporins. The 98 kDa nucleoporin is generated through a biogenesis pathway that involves synthesis and proteolytic cleavage of a 186 kDa precursor protein. This cleavage results in the 98 kDa nucleoporin as well as a 96 kDa nucleoporin, both of which are localized to the nucleoplasmic side of the NPC. Rat studies show that the 98 kDa nucleoporin functions as one of several docking site nucleoporins of transport substrates. The human gene has been shown to fuse to several genes following chromosome translocations in acute myelogenous leukemia (AML) and T-cell acute lymphocytic leukemia (T-ALL). This gene is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in several transcript variants\; however, not all variants have been fully described.

Alternative names and synonyms associated with Nucleoporin 98kDa (NUP98)

  • Nucleoporin 98-96 (Nup98-96) Elisa Kit
  • nucleoporin 98kDa (Nup98) Elisa Kit
  • nucleoporin 98kDa (NUP98) Elisa Kit
  • nucleoporin 98 (Nup98) Elisa Kit
  • nucleoporin 98 (nup98) Elisa Kit
  • Nup98 protein (nup98) Elisa Kit
  • 4732457F17 Elisa Kit
  • ADIR2 Elisa Kit
  • AI849286 Elisa Kit
  • CG10198 Elisa Kit
  • CG10201 Elisa Kit
  • Dmel\\CG10198 Elisa Kit
  • GB12688 Elisa Kit
  • im:7151238 Elisa Kit
  • l(3)95BCd Elisa Kit
  • Nup-98 Elisa Kit
  • Nup 96 Elisa Kit
  • NUP96 Elisa Kit
  • NUP98 Elisa Kit
  • Nup 98 Elisa Kit
  • nup98-96 Elisa Kit
  • Nup98-Nup96 Elisa Kit
  • Nup98/96 Elisa Kit
  • nup145 Elisa Kit
  • NUP196 Elisa Kit
  • zgc:63593 Elisa Kit
  • zgc:113968 Elisa Kit

Protein level used designations for Nucleoporin 98kDa (NUP98) ELISA Kits

CG10198-PA , CG10198-PC , CG10198-PD , Nup98 , Nup98-96-PA , Nup98-96-PC , Nup98-96-PD , nucleoporin 98 , nucleoporin 98-96 , nucleoporin98-96 , nucleoporin 98kD , nucleoporin 98kDa , nuclear pore complex protein Nup98-Nup96-like , nuclear pore complex protein Nup98-Nup96 , 98 kDa nucleoporin , nuclear pore complex protein Nup98 , nucleoporin Nup98 , GLFG-repeat containing nucleoporin , Nup98-Nup96

42816 Drosophila melanogaster
408335 Apis mellifera
450971 Pan troglodytes
587580 Strongylocentrotus purpuratus
100016427 Monodelphis domestica
100052986 Equus caballus
100090367 Ornithorhynchus anatinus
100414799 Callithrix jacchus
100475098 Ailuropoda melanoleuca
100522560 Sus scrofa
269966 Mus musculus
81738 Rattus norvegicus
777756 Danio rerio
430616 Gallus gallus
4928 Homo sapiens
476822 Canis lupus familiaris
540004 Bos taurus
100343626 Oryctolagus cuniculus
446233 Xenopus laevis
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