Browse our anti-TCF3 (TCF3) Antibodies

Full name:
anti-Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) Antibodies (TCF3)
On www.antibodies-online.com are 145 Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3) Antibodies from 25 different suppliers available. Additionally we are shipping TCF3 Proteins (7) and TCF3 Kits (6) and many more products for this protein. A total of 170 TCF3 products are currently listed.
Synonyms:
A1, AA408400, ALF2, AW209082, bhlhb21, e2a, E12, E12/E47, E47, G12, itf1, ME2, Pan1, Pan2, TCF-3, Tcf3, tcf3a, TCF7L1, tcfe2a, vdir, xtcf-3, xtcf3, zgc:113045

Most Popular Reactivities for anti-TCF3 (TCF3) Antibodies

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Top referenced anti-TCF3 Antibodies

  1. Human Polyclonal TCF3 Primary Antibody for FACS, IHC (p) - ABIN657912 : Hirose, Inukai, Kikuchi, Furukawa, Ikawa, Kawamoto, Oram, Göttgens, Kiyokawa, Miyagawa, Okita, Akahane, Zhang, Kuroda, Honna, Kagami, Goi, Kurosawa, Look, Matsui, Inaba, Sugita: Aberrant induction of LMO2 by the E2A-HLF chimeric transcription factor and its implication in leukemogenesis of B-precursor ALL with t(17;19). in Blood 2010 (PubMed)
    Show all 5 references for 657912

  2. Human Polyclonal TCF3 Primary Antibody for IHC, ELISA - ABIN1533168 : Kamps, Murre, Sun, Baltimore: A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL. in Cell 1990 (PubMed)
    Show all 3 references for 1533168

  3. Human Polyclonal TCF3 Primary Antibody for IHC, ELISA - ABIN1533624 : Nourse, Mellentin, Galili, Wilkinson, Stanbridge, Smith, Cleary: Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor. in Cell 1990 (PubMed)
    Show all 3 references for 1533624

  4. Human Polyclonal TCF3 Primary Antibody for IHC, ELISA - ABIN1532141 : Grimwood, Gordon, Olsen, Terry, Schmutz, Lamerdin, Hellsten, Goodstein, Couronne, Tran-Gyamfi, Aerts, Altherr, Ashworth, Bajorek, Black, Branscomb, Caenepeel, Carrano, Caoile, Chan, Christensen et al.: The DNA sequence and biology of human chromosome 19. ... in Nature 2004 (PubMed)
    Show all 3 references for 1532141

  5. Human Monoclonal TCF3 Primary Antibody for FACS, ELISA - ABIN1724729 : Firulli, Hadzic, McDaid, Firulli: The basic helix-loop-helix transcription factors dHAND and eHAND exhibit dimerization characteristics that suggest complex regulation of function. in The Journal of biological chemistry 2000 (PubMed)
    Show all 2 references for 1724729

  6. Cow (Bovine) Polyclonal TCF3 Primary Antibody for WB - ABIN2780485 : Amemiya-Kudo, Oka, Ide, Matsuzaka, Sone, Yoshikawa, Yahagi, Ishibashi, Osuga, Yamada, Murase, Shimano: Sterol regulatory element-binding proteins activate insulin gene promoter directly and indirectly through synergy with BETA2/E47. in The Journal of biological chemistry 2005 (PubMed)

More Antibodies against TCF3 Interaction Partners

Human Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3) interaction partners

  1. Poly (ADP-ribose) polymerase (show PARP1 Antibodies) inhibitors selectively induce cytotoxicity in TCF3-HLF (show EPAS1 Antibodies)-positive leukemic cells.

  2. MiR (show MLXIP Antibodies)-138 may be a tumor suppressor and potential prognostic biomarker in cervical cancer. Its downstream target, TCF3, may also regulate cancer development in a reverse manner as miR (show MLXIP Antibodies)-138.

  3. High levels of TCF3 in gliomas promote glioma development through the Akt (show AKT1 Antibodies) and Erk (show EPHB2 Antibodies) pathways.

  4. TWIST1 (show TWIST1 Antibodies)-E12 (show ELSPBP1 Antibodies) protein heterodimeric complexes may thus constitute the main active forms of TWIST1 (show TWIST1 Antibodies) with regard to senescence inhibition over the time course of breast tumorigenesis.

  5. Review of the role of the E2A-PBX1 (show PBX1 Antibodies) gene rearrangement in the prognosis of childhood acute lymphoblastic leukemia and its central nervous system relapse.

  6. Our data suggest that E2A antagonism of PU.1 activity contributes to its ability to commit multipotential hematopoietic progenitors to the lymphoid lineages.

  7. E47 is a novel substrate of PAK5 (show PAK6 Antibodies), and PAK5 (show PAK6 Antibodies)-mediated phosphorylation of E47 promotes epithelial-mesenchymal transition. High expression of phospho-E47 was associated with an aggressive phenotype of colon cancer and metastasis.

  8. We observed significant enrichment of the neuroactive ligand-receptor interaction pathway in TCF3-PBX1 (show PBX1 Antibodies) as well as an enrichment of genes involved in immunity and infection pathways in ETV6 (show ETV6 Antibodies)-RUNX1 (show RUNX1 Antibodies) subtype

  9. Over expression of E47 reprograms human pancreatic cancer cells to a quiescent acinar state with reduced tumorigenic potential.

  10. Drug response profiling of matched patient-derived xenografts revealed a distinct profile for TCF3-HLF (show EPAS1 Antibodies) ALL with resistance to conventional chemotherapeutics but sensitivity to glucocorticoids.

Mouse (Murine) Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3) interaction partners

  1. If Gfi1 (show ZNF163 Antibodies) levels fall below a threshold, Id1 (show ID1 Antibodies) expression increases and renders E2A unable to function, which prevents hematopoietic progenitors from engaging along the B lymphoid lineage

  2. these data identified E2A and E2-2 (show TCF4 Antibodies) as central regulators of B cell immunity.

  3. down-regulation of Id3 (show ID3 Antibodies) in B cells is essential for releasing E2A and E2-2 (show TCF4 Antibodies), which in a redundant manner are required for antigen-induced B cell differentiation.

  4. Data suggest a novel mechanism of drug resistance in which E2a and PRC2 drive changes in the B-cell epigenome; these alterations attenuate alkylating agent treatment-induced apoptosis.

  5. These findings suggest that miR (show MLXIP Antibodies)-506-3p played an important role in regulating NSC proliferation and differentiation via targeting TCF3 (show TCF7L1 Antibodies), and provide a promising avenue for future in-depth research into the functions of miR (show MLXIP Antibodies)-506-3p and TCF3 (show TCF7L1 Antibodies) in nervous system development.

  6. Conditional expression of E2A-HLF (show HLF Antibodies) induces B-cell precursor death and myeloproliferative-like disease in knock-in mice.

  7. Upregulation of E12/E47 by HBx ultimately and concomitant repression of E-cadherin (show CDH1 Antibodies) expression led to epithelial-mesenchymal transition in human hepatocytes.

  8. Mechanistically, E47 repressed the expression of several astrocyte-specific genes in adult NSPCs.

  9. Tcf3 (show TCF7L1 Antibodies) is upregulated in skin wounds and Tcf3 (show TCF7L1 Antibodies) overexpression accelerates keratinocyte migration and skin wound healing.

  10. Loss and gain of function analyses combined with in vivo studies in syngeneic breast cancer models demonstrate the participation of LOXL2 (show LOXL3 Antibodies) and E47 in tumor growth and their requirement for lung metastasis.

Xenopus laevis Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3) interaction partners

  1. Data indicte that Tcf-1 (show HNF1A Antibodies) and Lef-1 (show LEF1 Antibodies) exhibit a function in the axis induction assay, which is lacking in Tcf-3 and -4.

TCF3 Antigen Profile

Antigen Summary

This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1\;19), with PBX1), childhood leukemia (t(19\;19), with TFPT) and acute leukemia (t(12\;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.

Alternative names and synonyms associated with TCF3

  • transcription factor 3b (tcf3b) antibody
  • transcription factor 3 (TCF3) antibody
  • transcription factor 3 (Tcf3) antibody
  • transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) (tcf3) antibody
  • transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) (TCF3) antibody
  • transcription factor 7-like 1 (T-cell specific, HMG-box) (Tcf7l1) antibody
  • A1 antibody
  • AA408400 antibody
  • ALF2 antibody
  • AW209082 antibody
  • bhlhb21 antibody
  • e2a antibody
  • E12 antibody
  • E12/E47 antibody
  • E47 antibody
  • G12 antibody
  • itf1 antibody
  • ME2 antibody
  • Pan1 antibody
  • Pan2 antibody
  • TCF-3 antibody
  • Tcf3 antibody
  • tcf3a antibody
  • TCF7L1 antibody
  • tcfe2a antibody
  • vdir antibody
  • xtcf-3 antibody
  • xtcf3 antibody
  • zgc:113045 antibody

Protein level used designations for TCF3

transcription factor E2-alpha , transcription factor 3 , VDR interacting repressor , class B basic helix-loop-helix protein 21 , helix-loop-helix protein HE47 , immunoglobulin transcription factor 1 , kappa-E2-binding factor , negative vitamin D response element-binding protein , transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) , transcription factor ITF-1 , vitamin D receptor-interacting repressor , TCF-3 , immunoglobulin enhancer-binding factor E12/E47 , transcription factor A1 , transcription factor E2a , pancreas specific transcription factor 1c , transcription regulator Pan , transcription factor XE12/XE47 , class A basic helix-loop-helix transcription factor G12 , helix-loop-helix protein E12 , helix-loop-helix protein E47 , transcription factor 7-like 1 (T-cell specific, HMG-box) , transcription factor 7-like 1

GENE ID SPECIES
664768 Danio rerio
6929 Homo sapiens
21423 Mus musculus
171046 Rattus norvegicus
379355 Xenopus laevis
395146 Gallus gallus
485079 Canis lupus familiaris
530616 Bos taurus
312451 Rattus norvegicus
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