TCF3 antibody
Quick Overview for TCF3 antibody (ABIN1724729)
Target
See all TCF3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
-
-
Purpose
- TCF3 Antibody
-
Purification
- Ascitic fluid
-
Immunogen
- Purified recombinant fragment of human TCF3 expressed in E. Coli.
-
Isotype
- IgG1
-
-
-
-
Application Notes
-
ELISA: 1/10000
FCM: 1/200 - 1/400
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Ascitic fluid containing 0.03 % sodium azide.
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- 4 °C,-20 °C
-
Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
-
: "Inhibition of Tcf3 binding by I-mfa domain proteins." in: Molecular and cellular biology, Vol. 21, Issue 5, pp. 1866-73, (2001) (PubMed).
: "The basic helix-loop-helix transcription factors dHAND and eHAND exhibit dimerization characteristics that suggest complex regulation of function." in: The Journal of biological chemistry, Vol. 275, Issue 43, pp. 33567-73, (2000) (PubMed).
-
: "Inhibition of Tcf3 binding by I-mfa domain proteins." in: Molecular and cellular biology, Vol. 21, Issue 5, pp. 1866-73, (2001) (PubMed).
-
- TCF3 (Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3))
-
Alternative Name
- TCF3
-
Background
- Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer.
-
Molecular Weight
- 67.6 kDa
-
Gene ID
- 6929
-
UniProt
- P15923
-
Pathways
- WNT Signaling, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Production of Molecular Mediator of Immune Response
Target
-