Browse our anti-AKR1C2 (AKR1C2) Antibodies

Full name:
anti-Aldo-keto Reductase Family 1, Member C2 Antibodies (AKR1C2)
On are 74 Aldo-keto Reductase Family 1, Member C2 (AKR1C2) Antibodies from 15 different suppliers available. Additionally we are shipping AKR1C2 Proteins (9) and AKR1C2 Kits (6) and many more products for this protein. A total of 102 AKR1C2 products are currently listed.
AKR1C-pseudo, Akr1c21, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8
list all antibodies Gene Name GeneID UniProt
AKR1C2 1646 P52895
AKR1C2 291283 Q6AYQ2

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Top referenced anti-AKR1C2 Antibodies

  1. Human Polyclonal AKR1C2 Primary Antibody for EIA, WB - ABIN950320 : Setlur, Chen, Hossain, Ha, Van Doren, Stenzel, Steiner, Oldridge, Kitabayashi, Banerjee, Chen, Schäfer, Horninger, Lee, Rubin, Klocker, Demichelis: Genetic variation of genes involved in dihydrotestosterone metabolism and the risk of prostate cancer. in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010 (PubMed)
    Show all 3 references for 950320

  2. Human Monoclonal AKR1C2 Primary Antibody for ELISA, WB - ABIN514927 : Takahashi, Bains, Pfeifer, Grigliatti, Reid, Riggs: Aldo-keto reductase 1C2 fails to metabolize doxorubicin and daunorubicin in vitro. in Drug metabolism and disposition: the biological fate of chemicals 2008 (PubMed)
    Show all 2 references for 514927

  3. Human Polyclonal AKR1C2 Primary Antibody for IHC (p), WB - ABIN656180 : Wang, Chorley, Pittman, Kleeberger, Brothers, Liu, Spira, Bell: Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer. in PLoS ONE 2010 (PubMed)

  4. Human Polyclonal AKR1C2 Primary Antibody for WB - ABIN514925 : Ebert, Kisiela, Wsól, Maser: Proteasome inhibitors MG-132 and bortezomib induce AKR1C1, AKR1C3, AKR1B1, and AKR1B10 in human colon cancer cell lines SW-480 and HT-29. in Chemico-biological interactions 2011 (PubMed)

  5. Human Polyclonal AKR1C2 Primary Antibody for ELISA, WB - ABIN560582 : Su, Liao, Huang, Chu, Lin, Chang: Aldo-keto reductase 1C2 is essential for 1-nitropyrene's but not for benzo[a]pyrene's induction of p53 phosphorylation and apoptosis. in Toxicology 2008 (PubMed)

  6. Human Polyclonal AKR1C2 Primary Antibody for ELISA, WB - ABIN1534616 : Qin, Khanna, Cheng: Structure of a gene coding for human dihydrodiol dehydrogenase/bile acid-binding protein. in Gene 1994 (PubMed)

More Antibodies against AKR1C2 Interaction Partners

Human Aldo-keto Reductase Family 1, Member C2 (AKR1C2) interaction partners

  1. The reduction of DHT obese homozygotic twins could be linked to its increased degradation by AKR1C2 and HSD11B1 (show HSD11B1 Antibodies), and increased estrogen levels could be linked to increased adiposity-related expression of aromatase (show CYP19A1 Antibodies) in adipose tissue.

  2. the present study suggests that AKR1C1 (show DDH Antibodies), AKR1C2, AKR1C3 (show AKR1C3 Antibodies), and AKR1C4 (show AKR1C4 Antibodies) are closely associated with drug resistance to both CDDP and 5FU, and that mefenamic acid, an inhibitor of AKR1C, restores sensitivity through inhibition of drug-resistance in human cancer cells.

  3. We identified two powerful genes in the liver cancer metastasis process, AEG-1 (show MTDH Antibodies) and AKR1C2.

  4. Identify two novel factors, AKR1C2 (positive factor) and NF1 (show NF1 Antibodies) (negative factor), as the AEG-1 (show MTDH Antibodies) downstream players in the process of metastasis in liver cancer.

  5. The endogenous HMOX1 (show HMOX1 Antibodies) gene but not the AKR1C2 gene is strongly repressed by Bach1 (show BACH1 Antibodies) in HaCaT keratinocytes.

  6. In model cell lines of endometrial cancer, AKR1C2 and SRD5A1 (show SRD5A1 Antibodies) have crucial roles in progesterone metabolism.

  7. Significantly higher levels of SRD5A1 (show SRD5A1 Antibodies), AKR1C2, AKR1C3 (show AKR1C3 Antibodies), and HSD17B10 (show HSD17B10 Antibodies) mRNA were however found in bone metastases than in non-malignant and/or malignant prostate tissue

  8. The V54L mutation significantly decreases the 3alpha-hydroxysteroid dehydrogenase activity of DDH2 for the reduction of dihydrotestosterone.

  9. DDH2 expression might be a potential predictor and monitor of cisplatin efficacy in advanced NSCLC patients.

  10. Data suggest that interleukin-1beta facilitates progesterone metabolism in cervical fibroblasts by regulating expression of AKR1C1 (show DDH Antibodies) and AKR1C2.

AKR1C2 Antigen Profile

Antigen Summary

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.

Alternative names and synonyms associated with AKR1C2

  • aldo-keto reductase family 1, member C2 (AKR1C2) antibody
  • aldo-keto reductase family 1, member C2 (Akr1c2) antibody
  • AKR1C-pseudo antibody
  • Akr1c21 antibody
  • BABP antibody
  • DD antibody
  • DD2 antibody
  • DDH2 antibody
  • HAKRD antibody
  • HBAB antibody
  • MCDR2 antibody
  • SRXY8 antibody

Protein level used designations for AKR1C2

3-alpha-HSD3 , DD-2 , DD/BABP , aldo-keto reductase family 1 member C2 , chlordecone reductase homolog HAKRD , dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III , pseudo-chlordecone reductase , trans-1,2-dihydrobenzene-1,2-diol dehydrogenase , type II dihydrodiol dehydrogenase , 17-alpha-HSD , 17-alpha-hydroxysteroid dehydrogenase , 3(or 17)-alpha-hydroxysteroid dehydrogenase , 3-alpha-hydroxysteroid dehydrogenase , aldo-keto reductase family 1 member C21 , aldo-keto reductase family 1, member C21

1646 Homo sapiens
291283 Rattus norvegicus
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