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Browse our L1 Cell Adhesion Molecule Proteins (L1CAM)

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L1 Cell Adhesion Molecule Proteins (L1CAM)
On are 24 L1 Cell Adhesion Molecule (L1CAM) Proteins from 8 different suppliers available. Additionally we are shipping L1 Cell Adhesion Molecule Antibodies (274) and L1 Cell Adhesion Molecule Kits (40) and many more products for this protein. A total of 345 L1 Cell Adhesion Molecule products are currently listed.
CAML1, CD171, Hsas, HSAS1, Hyd, L1, l1cam-a, MASA, MIC5, N-CAM-L1, N-CAML1, NCAM-L1, NCAML1, S10, SPG1
list all proteins Gene Name GeneID UniProt
L1CAM 3897 P32004
L1CAM 16728  
Rat L1CAM L1CAM 50687 Q05695

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L1 Cell Adhesion Molecule Proteins (L1CAM) by Origin

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Top referenced L1 Cell Adhesion Molecule Proteins

  1. Human L1CAM Protein expressed in Human Cells - ABIN2002161 : Rosenthal, Jouet, Kenwrick: Aberrant splicing of neural cell adhesion molecule L1 mRNA in a family with X-linked hydrocephalus. in Nature genetics 1993 (PubMed)
    Show all 6 references for ABIN2002161

More Proteins for L1 Cell Adhesion Molecule Interaction Partners

Human L1 Cell Adhesion Molecule (L1CAM) interaction partners

  1. L1CAM expression is an independent predictor of poor survival in endometrial cancer, and is associated with advanced stage, high-risk endometrial cancer.

  2. L1CAM is a neuronal cell adhesion molecule (show NRCAM Proteins) involved in the development of the nervous system and progression of malignancies. (Review)

  3. Involvement of L1CAM in the regulation of activity of the canonical Wnt (show WNT2 Proteins) pathway and expression of genes of class I melanoma-associated (show ZNF654 Proteins) antigens in melanoma.

  4. L1CAM was a significant independent prognosticator for disease-specific survival in endometrial carcinoma.

  5. Report high frequency of L1CAM expression in high-risk endometrial cancers associated with mutant p53 (show TP53 Proteins) expression.

  6. L1CAM is frequently expressed in testicular germ cell tumors but not in normal testis.

  7. Our results suggest that the overexpression of L1CAM may be related to several established markers of poor prognosis in breast cancer patients.

  8. L1-CAM (show CALM1 Proteins) and N-CAM (show NCAM1 Proteins): From Adhesion Proteins to Pharmacological Targets

  9. the CE7-epitope of L1-CAM (show CALM1 Proteins) is a cell adhesion molecule (show MCAM Proteins) aberrantly expressed in several cancers and may have a role in immunotherapy

  10. novel missense variant in L1CAM was identified in two Caucasian families with mild-moderate intellectual disability without obvious L1 syndrome features

Mouse (Murine) L1 Cell Adhesion Molecule (L1CAM) interaction partners

  1. induced expression of L1CAM or PSA (show NPEPPS Proteins)-NCAM (show NCAM1 Proteins) in the iPSC-derived DA neurons cannot completely restore the neurite outgrowth potential that was reduced in these DA neurons as a consequence of epigenetic aberrations resulting from the iPSC reprogramming process.

  2. Heterozygous L1CAM-deficient mice express an autism-like phenotype.

  3. tumors in stressed animals demonstrated markedly enhanced expression of VEGFR-2 (show KDR Proteins) and L1CAM mRNA as well as pERK (show EIF2AK3 Proteins), MMP-2 (show MMP2 Proteins) and MMP-9 (show MMP9 Proteins) protein expression.

  4. Function-triggering antibodies to the adhesion molecule (show NCAM1 Proteins) L1 enhance recovery after injury of the adult mouse femoral nerve.

  5. We suggest that L1 stimulates neuritogenesis by activating CK2alpha leading to decreased levels of PTEN and p53 (show TP53 Proteins) via a novel, L1-triggered and CK2alpha-mediated signal transduction pathway.

  6. a positive relationship between L1 and pPKD1 in both cultured cerebellar neurons and human cerebellar tissue, suggesting that L1 functions in the modulation of PKD1 (show PKD1 Proteins) phosphorylation.

  7. Myelin basic protein (show MBP Proteins) cleaves cell adhesion molecule (show MCAM Proteins) L1 and promotes neuritogenesis and cell survival.

  8. These results demonstrate that L1 promotes neuronal differentiation from ESCs (show NR2E3 Proteins) through the L1-mediated enhancement of FUT9 (show FUT9 Proteins) and ST3Gal4 (show ST3GAL4 Proteins) expression.

  9. L1 stimulation triggers sumoylation and cleavage of L1, thus generating the L1-70 fragment which is cleaved by cathepsin E (show CTSE Proteins)

  10. the neurite outgrowth promoted by Neural Cell Adhesion Molecule L1 was strongly inhibited by siRNA against FGF21 (show FGF21 Proteins) gene or a treatment of cells with FGFR (show FGFR2 Proteins) inhibitor

L1 Cell Adhesion Molecule (L1CAM) Protein Profile

Protein Summary

The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.

Alternative names and synonyms associated with L1 Cell Adhesion Molecule (L1CAM)

  • L1 cell adhesion molecule (l1cam)
  • L1 cell adhesion molecule (L1CAM)
  • L1 cell adhesion molecule (L1cam)
  • CAML1 protein
  • CD171 protein
  • Hsas protein
  • HSAS1 protein
  • Hyd protein
  • L1 protein
  • l1cam-a protein
  • MASA protein
  • MIC5 protein
  • N-CAM-L1 protein
  • N-CAML1 protein
  • NCAM-L1 protein
  • NCAML1 protein
  • S10 protein
  • SPG1 protein

Protein level used designations for L1CAM

neural cell adhesion molecule L1 , antigen identified by monoclonal antibody R1 , N-CAM L1 , N-CAM-L1 , NCAM-L1 , NILE , nerve-growth factor-inducible large external glycoprotein , neuron-glia cell adhesion molecule (Ng-CAM) , neuronal-glial cell adhesion molecule , ng-CAM

373742 Xenopus laevis
3897 Homo sapiens
16728 Mus musculus
50687 Rattus norvegicus
492244 Canis lupus familiaris
516017 Bos taurus
396059 Gallus gallus
100726067 Cavia porcellus
100525324 Sus scrofa
100328746 Oryctolagus cuniculus
101110032 Ovis aries
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