L1CAM Products
(L1 Cell Adhesion Molecule (L1CAM))
Categories
The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant. [provided by RefSeq, Jul 2008].
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Featured L1CAM Categories
L1CAM Antibodies
High quality antibodies with extensive validation data.
L1CAM ELISA Kits
Reliable ELISA kits for a wide range of species.
L1CAM Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended L1CAM Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IHC, ELISA
Validations
- (4)
Cat. No.
ABIN7189451
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS
Validations
- (4)
Cat. No.
ABIN7193538
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Dog, Human, Monkey
Application
WB, FACS, IF
Validations
- (4)
Cat. No.
ABIN1499086
Quantity
100 μL
Datasheet
Datasheet
Recommended L1CAM ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (5)
Cat. No.
ABIN6720565
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957349
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957350
Quantity
96 tests
Datasheet
Datasheet
Recommended L1CAM Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275124
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275127
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1309092
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our L1CAM products
: "Circulating Levels of L1-cell Adhesion Molecule as a Serum Biomarker for Early Detection of Gastric Cancer and Esophagogastric Junction Adenocarcinoma." in: Journal of Cancer, Vol. 11, Issue 18, pp. 5395-5402, (2020) (PubMed).: "Glioma malignancy is linked to interdependent and inverse AMOG and L1 adhesion molecule expression." in: BMC cancer, Vol. 19, Issue 1, pp. 911, (2020) (PubMed).
: "The Diagnostic Value of Serum L1CAM in Patients With Colorectal Cancer." in: Technology in cancer research & treatment, Vol. 19, pp. 1533033820920971, (2020) (PubMed).
: "L1 Cell Adhesion Molecule Overexpression Down Regulates Phosphacan and Up Regulates Structural Plasticity-Related Genes Rostral and Caudal to the Complete Spinal Cord Transection." in: Journal of neurotrauma, Vol. 37, Issue 3, pp. 534-554, (2020) (PubMed).
: "Review of ependymomas: assessment of consensus in pathological diagnosis and correlations with genetic profiles and outcome." in: Brain tumor pathology, Vol. 36, Issue 2, pp. 92-101, (2019) (PubMed).
: "Endometrial cancer prognosis correlates with the expression of L1CAM and miR34a biomarkers." in: Journal of experimental & clinical cancer research : CR, Vol. 37, Issue 1, pp. 139, (2018) (PubMed).
: "Expression of neural cell adhesion molecule L1 (CD171) in neuroectodermal and other tumors: An immunohistochemical study of 5155 tumors and critical evaluation of CD171 prognostic value in ..." in: Oncotarget, Vol. 7, Issue 34, pp. 55276-55289, (2018) (PubMed).
: "The sL1CAM in sera of patients with endometrial and ovarian cancers." in: Archives of gynecology and obstetrics, Vol. 295, Issue 1, pp. 225-232, (2016) (PubMed).
: "Angiogenic cytokines are antibody targets during graft-versus-leukemia reactions." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 21, Issue 5, pp. 1010-8, (2015) (PubMed).
: "Potentials and capabilities of the Extracellular Vesicle (EV) Array." in: Journal of extracellular vesicles, Vol. 4, pp. 26048, (2015) (PubMed).
Synonyms and alternative names related to L1CAM
L1 cell adhesion molecule S homeolog (l1cam.S), L1 cell adhesion molecule (L1CAM), L1 cell adhesion molecule (L1cam), CAML1, CD171, HSAS, Hsas, HSAS1, Hyd, L1, l1cam-a, MASA, MIC5, N-CAM-L1, N-CAML1, NCAM-L1, NCAML1, S10, SPG1Protein level used designations for L1CAM
- neural cell adhesion molecule L1
- antigen identified by monoclonal antibody R1
- N-CAM L1
- N-CAM-L1
- NCAM-L1
- NILE
- nerve-growth factor-inducible large external glycoprotein
- neuron-glia cell adhesion molecule (Ng-CAM)
- neuronal-glial cell adhesion molecule
- ng-CAM
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