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L1CAM Protein (AA 20-1123) (His tag)

L1CAM Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7275127
  • Target See all L1CAM Proteins
    L1CAM (L1 Cell Adhesion Molecule (L1CAM))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 20-1123
    Origin
    • 11
    • 5
    • 2
    Mouse
    Source
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This L1CAM protein is labelled with His tag.
    Purpose
    Mouse L1CAM Protein
    Sequence
    Ile20-Glu1123
    Characteristics
    Recombinant Mouse L1CAM Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ile20-Glu1123.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product L1CAM Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    L1CAM (L1 Cell Adhesion Molecule (L1CAM))
    Alternative Name
    L1CAM (L1CAM Products)
    Synonyms
    l1cam-a Protein, CAML1 Protein, CD171 Protein, HSAS Protein, HSAS1 Protein, MASA Protein, MIC5 Protein, N-CAM-L1 Protein, N-CAML1 Protein, NCAM-L1 Protein, S10 Protein, SPG1 Protein, L1 Protein, Hsas Protein, Hyd Protein, NCAML1 Protein, L1 cell adhesion molecule S homeolog Protein, L1 cell adhesion molecule Protein, l1cam.S Protein, L1CAM Protein, L1cam Protein
    Background
    L1 cell adhesion molecule (L1CAM) is one of the first neural adhesion molecules described with important functions in the development of the nervous system. Subsequent work discovered that L1CAM is expressed in many human cancers and is often associated with bad prognosis. This is most likely due to the motility and invasion promoting function of L1CAM. L1CAM is a valuable diagnostic/prognostic marker and an attractive target for the therapy of several human cancers.
    Molecular Weight
    125.4 kDa. Due to glycosylation, the protein migrates to 160-180 kDa based on Tris-Bis PAGE result.
    UniProt
    P11627
    Pathways
    Synaptic Membrane
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