Browse our PTPRD Proteins (PTPRD)

Full name:
Protein tyrosine Phosphatase, Receptor Type, D Proteins (PTPRD)
On are 8 Protein tyrosine Phosphatase, Receptor Type, D (PTPRD) Proteins from 3 different suppliers available. Additionally we are shipping PTPRD Antibodies (30) and many more products for this protein. A total of 42 PTPRD products are currently listed.
1110002J03Rik, 3000002J10Rik, B230219D21Rik, HPTP, HPTPD, HPTPDELTA, PTPD, R-PTP-delta, RPTPDELTA
list all proteins Gene Name GeneID UniProt
PTPRD 5789 P23468
PTPRD 19266 Q64487
Rat PTPRD PTPRD 313278  

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PTPRD Proteins (PTPRD) by Origin

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Human Protein tyrosine Phosphatase, Receptor Type, D (PTPRD) interaction partners

  1. Mutation in PTPRD gene is associated with nodal marginal zone lymphoma.

  2. Low PTPRD expression is associated with Head and Neck Squamous Cell Carcinoma.

  3. The data provide evidence of the high incidence of PTPRD inactivation in laryngeal squamous cell carcinoma, suggesting that deletions and loss-of-function mutations are responsible for PTPRD loss only in a fraction of cases, whereas DNA methylation (show HELLS Proteins) is the dominating mechanism of PTPRD inactivation.

  4. PTPRD polymorphisms might modulate antipsychotic-induced weight gain.

  5. PTPRD was identified as a novel locus potentially associated with blood pressure response to atenolol and resistant hypertension in multiple ethnic groups.

  6. PTPRD mutation, but not methylation or copy number loss, may serve as a predictive biomarker of sensitivity to STAT3 (show STAT3 Proteins) inhibitors in HNSCC.

  7. Study shows for the first time that DNMT1 (show DNMT1 Proteins) caused PTPRD DNA hypermethylation and induced insulin (show INS Proteins) signaling silencing in T2D patients.

  8. PTPRD is homozygously deleted and epigenetically downregulated in hepatocellular carcinomas (HCCs (show HCCS Proteins)).

  9. This study demonstrated that the copy number variations of PTPRD relate to opioid dependence.

  10. Silencing PTPRD expression by siRNA treatment significantly enhanced cell proliferation compared with mock siRNA treatment.

Mouse (Murine) Protein tyrosine Phosphatase, Receptor Type, D (PTPRD) interaction partners

  1. Chondroitin Sulfate Proteoglycans Negatively Modulate Spinal Cord Neural Precursor Cells by Signaling Through LAR (show PTPRF Proteins) and RPTPsigma (show PTPRS Proteins) and Modulation of the Rho/ROCK Pathway.

  2. Ptprd is a tumor suppressor that can promote tumorigenesis in concert with Cdkn2a loss.

  3. We reveal that PTPRD is a bona fide tumor suppressor, pinpoint PTPRD loss as a cause of aberrant STAT3 activation in gliomas, and establish PTPRD loss, in the setting of CDKN2A/p16(INK4A) deletion, as a driver of glioma progression.

  4. RPTP-sigma (show PTPRS Proteins) and RPTP-delta complement each other functionally during mammalian development, and reveal an essential contribution of RPTP-sigma (show PTPRS Proteins) and RPTP-delta to appropriate motoneuron axon targeting during mammalian axonogenesis.

  5. Receptor protein tyrosine phosphatase (show PTPRT Proteins)-delta cooperates with hedgehog (show SHH Proteins)-responsive gene MIM (show MTSS1 Proteins) to induce cytoskeletal remodeling.

  6. PTPRD may be one of a select group of tumor suppressor genes that are inactivated in a wide range of common tumor types.

PTPRD Protein Profile

Protein Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5.

Alternative names and synonyms associated with PTPRD

  • protein tyrosine phosphatase, receptor type, D (PTPRD)
  • protein tyrosine phosphatase, receptor type, D (Ptprd)
  • 1110002J03Rik protein
  • 3000002J10Rik protein
  • B230219D21Rik protein
  • HPTP protein
  • HPTPD protein
  • HPTPDELTA protein
  • PTPD protein
  • R-PTP-delta protein
  • RPTPDELTA protein

Protein level used designations for PTPRD

R-PTP-delta , protein tyrosine phosphatase, receptor type, delta polypeptide , protein-tyrosine phosphatase delta , receptor-type tyrosine-protein phosphatase delta

100051885 Equus caballus
5789 Homo sapiens
19266 Mus musculus
431602 Gallus gallus
481538 Canis lupus familiaris
100155429 Sus scrofa
532751 Bos taurus
313278 Rattus norvegicus
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