PTPRD Protein (partial) (His tag)

Catalog No. ABIN5608459

Product Details

Target: PTPRD (Protein tyrosine Phosphatase, Receptor Type, D (PTPRD))

Protein Type: Recombinant

Protein Characteristics: partial

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This PTPRD protein is labelled with His tag.

Application: Western Blotting (WB)

Sequence: Glu 21 - Glu 1265

Purity: >90 % as determined by SDS-PAGE.

Endotoxin Level: Endotoxin level is less than 1.0 EU per ug by the LAL method.

Application Details

Application Notes: This recombinant protein can be used for WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C,-80 °C

Storage Comment: Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.

Target Details

Target: PTPRD (Protein tyrosine Phosphatase, Receptor Type, D (PTPRD))

Alternative Name: PTPRD (PTPRD Products)

Synonyms: HPTP Protein, HPTPD Protein, HPTPDELTA Protein, PTPD Protein, RPTPDELTA Protein, 1110002J03Rik Protein, 3000002J10Rik Protein, B230219D21Rik Protein, R-PTP-delta Protein, ptprd Protein, zgc:165626 Protein, ptpdelta Protein, rptpdelta Protein, xptp-d Protein, protein tyrosine phosphatase, receptor type D Protein, protein tyrosine phosphatase, receptor type, D Protein, receptor-type tyrosine-protein phosphatase delta Protein, protein tyrosine phosphatase, receptor type, D, b Protein, protein tyrosine phosphatase, receptor type D S homeolog Protein, PTPRD Protein, Ptprd Protein, LOC100155429 Protein, ptprdb Protein, ptprd.S Protein

Background: Receptor-type tyrosine-protein phosphatase delta is an enzyme that is encoded by the PTPRD gene. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPRD has been shown to interact with PTPRS and liprin-alpha-1. Studies of the similar genes in chick and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple tissue specific alternatively spliced transcript variants of this gene have been reported. Mutations in the PTPRD gene are associated with autism, obsessive-compulsive disorder, and breast cancer.

Molecular Weight: 140 kDa

Gene ID: 5789

NCBI Accession: NP_002830

Pathways: Synaptic Membrane