PTPRD Protein (AA 21-1265) (His tag)
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- Target See all PTPRD Proteins
- PTPRD (Protein tyrosine Phosphatase, Receptor Type, D (PTPRD))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-1265
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PTPRD protein is labelled with His tag.
- Sequence
- AA 21-1265
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 140 kDa. The protein migrates as 19 kDa and 120-130 kDa under reducing (R) condition (SDS-PAGE).
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product PTPRD Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
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- Target
- PTPRD (Protein tyrosine Phosphatase, Receptor Type, D (PTPRD))
- Alternative Name
- PTPRD (PTPRD Products)
- Synonyms
- HPTP Protein, HPTPD Protein, HPTPDELTA Protein, PTPD Protein, RPTPDELTA Protein, 1110002J03Rik Protein, 3000002J10Rik Protein, B230219D21Rik Protein, R-PTP-delta Protein, ptprd Protein, zgc:165626 Protein, ptpdelta Protein, rptpdelta Protein, xptp-d Protein, protein tyrosine phosphatase, receptor type D Protein, protein tyrosine phosphatase, receptor type, D Protein, receptor-type tyrosine-protein phosphatase delta Protein, protein tyrosine phosphatase, receptor type, D, b Protein, protein tyrosine phosphatase, receptor type D S homeolog Protein, PTPRD Protein, Ptprd Protein, LOC100155429 Protein, ptprdb Protein, ptprd.S Protein
- Background
- Receptor-type tyrosine-protein phosphatase delta is an enzyme that is encoded by the PTPRD gene. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPRD has been shown to interact with PTPRS and liprin-alpha-1. Studies of the similar genes in chick and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple tissue specific alternatively spliced transcript variants of this gene have been reported. Mutations in the PTPRD gene are associated with autism, obsessive-compulsive disorder, and breast cancer.
- Molecular Weight
- 140.0 kDa
- NCBI Accession
- NP_002830
- Pathways
- Synaptic Membrane
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