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SNCA Proteins

(Synuclein, alpha (SNCA))
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009].
SNCA Protein (Ala53Thr-Mutant) SNCA Protein (Ala53Thr-Mutant) SNCA Protein (Ala53Thr-Mutant) (ABIN6952303)

SNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS, WB, in vitro, in vivo Active

SNCA Protein (full length) SNCA Protein (full length) SNCA Protein (full length) (ABIN5651245)

SNCA Origin: Mouse Host: Escherichia coli (E. coli) Recombinant SDS, WB, in vitro, in vivo Active

SNCA Protein (full length) SNCA Protein (full length) SNCA Protein (full length) (ABIN5065829)

SNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant >95% pure using SDS-PAGE analysis. SDS, WB, in vitro, in vivo Active

SNCA Proteins by Grade

Find SNCA Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

SNCA Proteins by Origin

Find SNCA Proteins for a variety of species such as anti-Human SNCA, anti-Mouse SNCA, anti-Rat SNCA. The species listed below are among those available. Click on a link to go to the corresponding products.

SNCA Proteins by Source

Here you will find SNCA Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

SNCA Proteins by Protein Type

Here you can find SNCA Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

SNCA Proteins by Application

Find SNCA Proteins validated for a specific application such as ELISA, WB, SDS, in vitro. Some of the available applications are listed below. Click on a link to go to the corresponding products.

SNCA Proteins by Biological Activity

Find SNCA Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular SNCA Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (6)
Cat. No. ABIN6952303
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (9)
Cat. No. ABIN5651245
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (10)
Cat. No. ABIN5065829
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse, Rat
Source Rabbit
Validations
  • (1)
  • (4)
Cat. No. ABIN1742284
Quantity 200 μL
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7320688
Quantity 50 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125301
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7320687
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7504231
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505128
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505351
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7319207
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN4371752
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7393487
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7405657
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (3)
  • (1)
Cat. No. ABIN1046507
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our SNCA Proteins

Xu, Li, Qin, Zhu, Zhou, Shi, Wang, Hu, Fan, Li: "Unraveling the role of hydrogen peroxide in ?-synuclein aggregation using an ultrasensitive nanoplasmonic probe." in: Analytical chemistry, Vol. 87, Issue 3, pp. 1968-73, (2015) (PubMed).

Jüttner, Moré, Das, Babich, Meier, Henning, Erdmann, Mu Ller, Otto, Grantyn, Rathjen: "Impaired synapse function during postnatal development in the absence of CALEB, an EGF-like protein processed by neuronal activity." in: Neuron, Vol. 46, Issue 2, pp. 233-45, (2005) (PubMed).

Uéda, Saitoh, Mori: "Tissue-dependent alternative splicing of mRNA for NACP, the precursor of non-A beta component of Alzheimer's disease amyloid." in: Biochemical and biophysical research communications, Vol. 205, Issue 2, pp. 1366-72, (1995) (PubMed).

Campion, Martin, Heilig, Charbonnier, Moreau, Flaman, Petit, Hannequin, Brice, Frebourg: "The NACP/synuclein gene: chromosomal assignment and screening for alterations in Alzheimer disease." in: Genomics, Vol. 26, Issue 2, pp. 254-7, (1995) (PubMed).

Uéda, Fukushima, Masliah, Xia, Iwai, Yoshimoto, Otero, Kondo, Ihara, Saitoh: "Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 23, pp. 11282-6, (1994) (PubMed).

Aliases for SNCA Proteins

synuclein alpha L homeolog (snca.L) Proteins
alpha-synuclein (LOC619283) Proteins
synuclein alpha (SNCA) Proteins
synuclein, alpha (Snca) Proteins
synuclein alpha (Snca) Proteins
alphaSYN Proteins
LOC619283 Proteins
MGC64356 Proteins
NACP Proteins
PARK1 Proteins
PARK4 Proteins
PD1 Proteins
snca Proteins
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