SNCA Products
(Synuclein, alpha (SNCA))
Categories
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009].
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Featured SNCA Categories
SNCA Antibodies
High quality antibodies with extensive validation data.
SNCA ELISA Kits
Reliable ELISA kits for a wide range of species.
SNCA Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SNCA Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (7)
Cat. No.
ABIN6254965
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (5)
Cat. No.
ABIN5650936
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (5)
Cat. No.
ABIN5650949
Quantity
100 μL
Datasheet
Datasheet
Recommended SNCA ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6962177
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (5)
- (1)
Cat. No.
ABIN6959829
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (3)
- (1)
Cat. No.
ABIN6959830
Quantity
96 tests
Datasheet
Datasheet
Recommended SNCA Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (6)
Cat. No.
ABIN6952303
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (9)
Cat. No.
ABIN5651245
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (10)
Cat. No.
ABIN5065829
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our SNCA products
: "Neurorestorative effects of sub-chronic administration of ambroxol in rodent model of Parkinson's disease." in: Naunyn-Schmiedeberg's archives of pharmacology, Vol. 393, Issue 3, pp. 429-444, (2021) (PubMed).: "Potential therapeutic effects of antagonizing adenosine A2A receptor, curcumin and niacin in rotenone-induced Parkinson's disease mice model." in: Molecular and cellular biochemistry, Vol. 465, Issue 1-2, pp. 89-102, (2020) (PubMed).
: "Nose to brain delivery of rotigotine loaded chitosan nanoparticles in human SH-SY5Y neuroblastoma cells and animal model of Parkinson's disease." in: International journal of pharmaceutics, Vol. 579, pp. 119148, (2020) (PubMed).
: "Anti-α-synuclein ASO delivered to monoamine neurons prevents α-synuclein accumulation in a Parkinson's disease-like mouse model and in monkeys." in: EBioMedicine, Vol. 59, pp. 102944, (2020) (PubMed).
: "Exosomes from patients with Parkinson's disease are pathological in mice." in: Journal of molecular medicine (Berlin, Germany), Vol. 97, Issue 9, pp. 1329-1344, (2020) (PubMed).
: "Ambroxol modulates 6-Hydroxydopamine-induced temporal reduction in Glucocerebrosidase (GCase) enzymatic activity and Parkinson's disease symptoms." in: Biochemical pharmacology, Vol. 155, pp. 479-493, (2019) (PubMed).
: "Neurodegenerative Disease-Related Proteins within the Epidermal Layer of the Human Skin." in: Journal of Alzheimer's disease : JAD, Vol. 69, Issue 2, pp. 463-478, (2019) (PubMed).
: "Rosmarinic acid attenuates inflammatory responses through inhibiting HMGB1/TLR4/NF-κB signaling pathway in a mouse model of Parkinson's disease." in: Life sciences, Vol. 223, pp. 158-165, (2019) (PubMed).
: "An Enriched Environment Ameliorates Oxidative Stress and Olfactory Dysfunction in Parkinson's Disease with α-Synucleinopathy." in: Cell transplantation, Vol. 27, Issue 5, pp. 831-839, (2019) (PubMed).
: "Apelin-36 mitigates MPTP/MPP+-induced neurotoxicity: Involvement of α-synuclein and endoplasmic reticulum stress." in: Brain research, Vol. 1721, pp. 146334, (2019) (PubMed).
Synonyms and alternative names related to SNCA
synuclein alpha L homeolog (snca.L), alpha-synuclein (LOC619283), synuclein alpha (SNCA), synuclein, alpha (Snca), synuclein alpha (Snca), alphaSYN, LOC619283, MGC64356, NACP, PARK1, PARK4, PD1, sncaProtein level used designations for SNCA
- synuclein, alpha
- alpha-synuclein
- alpha SYN
- non-A beta component of AD amyloid
- non-A4 component of amyloid
- non A-beta component of AD amyloid
- synuclein alpha-140
- alpha synuclein
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