Browse our CD28 Proteins (CD28)

On are 35 CD28 Proteins from 10 different suppliers available. Additionally we are shipping CD28 Antibodies (948) and CD28 Kits (35) and many more products for this protein. A total of 1037 CD28 products are currently listed.
CD28RNA, Tp44
list all proteins Gene Name GeneID UniProt
CD28 12487 P31041
CD28 940 P10747
CD28 25660 P31042

CD28 Proteins (CD28) by Origin

More Proteins for CD28 Interaction Partners

Mouse (Murine) CD28 interaction partners

  1. results are consistent with a complex pathway in which CD28 is the primary driver of Treg proliferation and CTLA-4 (show CTLA4 Proteins) functions as the main brake but is also dependent on TCR signals and interactions with CD80 (show CD80 Proteins)/CD86 (show CD86 Proteins).

  2. data suggest that mPEG PV1 (show PLVAP Proteins)-Fab (show FANCB Proteins)' acts mainly on IFN-gamma (show IFNG Proteins)-producing CD4 (show CD4 Proteins)+ T cells and emphasize that this specific CD28 blockade strategy is a potential specific and alternative tool for the treatment of autoimmune disorders in the eye.

  3. the scaffolding role of RLTPR predominates during CD28 co-stimulation and underpins the similar function of RLTPR in human and mouse T cells.

  4. BAFF (show TNFSF13B Proteins) upregulates CD28/B7 and CD40 (show CD40 Proteins)/CD154 (show CD40LG Proteins) expression, and promotes the interactions between T and B cells in a BAFF-R (show TNFRSF13C Proteins)-dependent manner

  5. we report that cell-intrinsic deletion of CD28 after the peak of the primary response does not affect the establishment, maintenance, or recall of long-term memory. Thus, if given sufficient time, the progeny of primed CD8 (show CD8A Proteins)(+) T cells adapt to the absence of this costimulator.

  6. Deletion of CD28 co-stimulatory signals exacerbates left ventricular remodeling and increases cardiac rupture after MI through prolongation of the inflammatory period and reduction of collagen fiber in the infarct scars.

  7. identified a new plasmacytoid dendritic cells regulatory mechanism by which the same CD28 molecule that promotes stimulation in most cells

  8. Ndrg1 (show NDRG1 Proteins) is phosphorylated and degraded by CD28 signalling in a proteasome-dependent manner.

  9. The CD4/CD8 positive lymphocyte count and the expression of CD28 and CD38 antigens in the murine schistosomiasis japonica model are reported.

  10. results suggest a key role for CD28 costimulation in promoting a central Treg to eTreg transition with appropriate upregulation of chemokine (show CCL1 Proteins) receptors such as CCR6 (show CCR6 Proteins) that are required for tissue homing

Human CD28 interaction partners

  1. identified recurrent mutations in CD28 in peripheral T-cell lymphomas. Molecular modeling studies on each of these mutations suggested how these mutants result in increased affinities.

  2. the scaffolding role of RLTPR predominates during CD28 co-stimulation and underpins the similar function of RLTPR in human and mouse T cells.

  3. Our data show that mast cells can costimulate human CD4 (show CD4 Proteins)(+) T cells to induce strong T-cell proliferation, but that therapies aiming at disrupting the interaction of CD28 and B7 molecules do not inhibit mast cell mediated T-cell activation.

  4. High CD28 Circulating Levels are associated with Breast Cancer.

  5. The CTLA4 (show CTLA4 Proteins)-CD28 gene fusion is likely a major contributor to the pathogenesis of T-cell lymphomas and represents a potential target for anti-CTLA4 (show CTLA4 Proteins) cancer immunotherapy.

  6. Following phosphorylation of the tyrosine, the proteins growth factor receptor-bound protein 2 (Grb2 (show GRB2 Proteins)), Grb2 (show GRB2 Proteins)-related adaptor downstream of Shc (show SHC1 Proteins) (Gads (show GRAP2 Proteins)), and p85 subunit of phosphoinositide 3-kinase may bind to pYMNM (where pY is phosphotyrosine) via their Src (show SRC Proteins) homology 2 (SH2) domains, leading to downstream signaling to distinct immune pathways. These three adaptor proteins bind to the same site on CD28 with variable affinity

  7. CD28 family receptors are potential clinical indicators for the rapid monitoring of changes in T cell function during CHB treatment.

  8. The eQTL mapping analysis revealed that the variations in CD28 and NFKB1 gene content might affect the abundance of transcripts of CD28 and Family with sequence similarity 177 member A1 (FAM177A1) genes, respectively. These results suggest that CD28 and NFKB1 gene variants may be associated with increased risks to IRM.

  9. this study shows that CD28 contributes to rheumatoid arthritis susceptibility in Egyptian

  10. A highly recurrent novel missense mutation in CD28 among angioimmunoblastic T-cell lymphoma patients.

CD28 Protein Profile

Protein Summary

The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with CD28

  • CD28 molecule (CD28)
  • CD28 antigen (Cd28)
  • Cd28 molecule (Cd28)
  • CD28RNA protein
  • Tp44 protein

Protein level used designations for CD28 Proteins (CD28)

CD28 antigen , T-cell-specific surface glycoprotein CD28 , CD28 antigen (Tp44) , CHT28 , T-cell-specific surface glycoprotein CD28 homolog , T-cell costimulatory molecule CD28 , cell surface protein , costimulatory molecule B7 receptor CD28 , antigen CD28 , T-cell specific surface glycoprotein CD28

100067829 Equus caballus
12487 Mus musculus
940 Homo sapiens
25660 Rattus norvegicus
396249 Gallus gallus
100126555 Meleagris gallopavo
403646 Canis lupus familiaris
281050 Bos taurus
493802 Felis catus
100008998 Oryctolagus cuniculus
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