Browse our anti-HLA-DRB3 (HLA-DRB3) Antibodies

Full name:
anti-HLA Class II DR beta 3 Antibodies (HLA-DRB3)
On www.antibodies-online.com are 27 HLA Class II DR beta 3 (HLA-DRB3) Antibodies from 11 different suppliers available. Additionally we are shipping HLA-DRB3 Proteins (3) and many more products for this protein. A total of 34 HLA-DRB3 products are currently listed.
Synonyms:
HLA-DR3B
list all antibodies Gene Name GeneID UniProt
HLA-DRB3 3125 P79483
HLA-DRB3    
HLA-DRB3    

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More Antibodies against HLA-DRB3 Interaction Partners

Human HLA Class II DR beta 3 (HLA-DRB3) interaction partners

  1. In contrast to HLA-DRB4 (show HLADRB4 Antibodies)*01:01P, the inheritance of HLA-DRB3*01:01 is strongly associated with the propensity for mounting a humoral immune response against fetal HPA (show HPSE Antibodies)-1a antigen.

  2. our findings provide clear evidence that the HLA-DRB1 (show HLA-DRB1 Antibodies)*15:01 and HLA-DRB3*02:02 alleles independently and strongly associate with phospholipase A2 (show YWHAZ Antibodies) receptor related idiopathic membranous nephropathy in the Chinese population

  3. The first time that the haplotypes A33-DR3 and A33-DR9 were found with an enhanced predisposition to type 1 diabetes in Han Chinese.

  4. HLA-DRB3 affects type 1 diabetes risk and islet autoantibodies.

  5. this mouse model unravels a critical role for HLA-DR3 (show TNFRSF25 Antibodies) in generating an autoimmune response to SmD and lupus nephritis in the NZM2328 background.

  6. Haplotyping was done on 91 Southern Europe celiac patients. HLA-DR3 (show TNFRSF25 Antibodies)-DQ2 (show TOR1A Antibodies) without HLA-DR7-DQ2 (show TOR1A Antibodies) was present in 62.6%, HLA-DR7-DQ2 (show TOR1A Antibodies) without HLA-DR3 (show TNFRSF25 Antibodies)-DQ2 (show TOR1A Antibodies) was present in 16.5% and HLA-DR4 (show HLADRB4 Antibodies)-DQ8 without HLA-DQ2 (show TOR1A Antibodies) was present in 3.3%.

  7. Children with the HLA haplotype DR3 (show TNFRSF25 Antibodies)-DQ2 (show TOR1A Antibodies), especially homozygotes, were found to be at high risk for celiac disease autoimmunity and celiac disease early in childhood.

  8. The unusual DRB1 (show RBM45 Antibodies)*08:01 haplotype carrying DRB3*02:02 has been confirmed in a Dutch family.

  9. HLA-DRB3*02:02 on the DRB1 (show RBM45 Antibodies)*03:01 haplotype can contribute to type 1 diabetes risk.

  10. Prospective evaluation of matching for HLA-DRB3/4/5, -DQ, and -DP loci is warranted to reduce posttransplant risks in donor-recipient pairs matched for 7/8 HEL.

HLA-DRB3 Antigen Profile

Antigen Summary

HLA-DRB3 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5. The presence of DRB3 is linked with allelic variants of DRB1, otherwise it is omitted. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9.

Alternative names and synonyms associated with HLA-DRB3

  • major histocompatibility complex, class II, DR beta 3 (HLA-DRB3) antibody
  • HLA-DR3B antibody

Protein level used designations for HLA-DRB3

DR7 , HLA class II histocompatibility antigen, DR beta 3 chain , HLA class II histocompatibility antigen, DRB1-7 beta chain , MHC class II HLA-DR beta 3 chain , MHC class II antigen DR beta 3 chain , MHC class II antigen DRB3 , human leucocyte antigen DRB3

GENE ID SPECIES
3125 Homo sapiens
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