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Human Vimentin Protein expressed in Wheat germ - ABIN1325010
Kim, Nakamura, Lee, Hong, Pérez-Sala, McCulloch: Regulation of cell adhesion to collagen via beta1 integrins is dependent on interactions of filamin A with vimentin and protein kinase C epsilon. in Experimental cell research 2010
This study evaluated the expression pattern of vimentin in testes of mature Arabian stallions and correlated its distribution with grade of seminiferous tubule impairment as indicated by a Johnsen score.
Vimentin- like transcript was expressed in both chordocytes and chordoblasts, whereas the elastin (show ELN Proteins)- like transcript was uniquely expressed in the chordoblasts lining the notochordal sheath.
our findings suggest that the HIF-1alpha (show HIF1A Proteins)-HDAC1 (show HDAC1 Proteins) complex transcriptionally inhibits miR (show MLXIP Proteins)-548an expression during hypoxia, resulting in the upregulation of vimentin that facilitates the pancreatic tumorigenesis.
Rab7a (show RAB7A Proteins) depletion decreases the amount of active Rac1 but not its abundance and reduces the number of cells with vimentin filaments facing the wound, indicating that Rab7a (show RAB7A Proteins) has a role in the orientation of vimentin filaments during migration
Over-expression of TNC (show TNC Proteins), SMA (show SMN1 Proteins), and vimentin were significantly correlated with the lower overall survival in prostate cancer patients.
Results show that VIM mRNA is regulated in melanoma by UNR (show P2RY4 Proteins) protein.
These findings suggest that Plk1 regulates smooth muscle contraction by modulating vimentin phosphorylation at Ser (show SIGLEC1 Proteins)-56.
Structural Dynamics of the Vimentin Coiled-coil Contact Regions Involved in Filament Assembly as Revealed by Hydrogen-Deuterium Exchange.(
These findings are the first to demonstrate that vimentin is critical for influenza viral infection as it facilitates endosomal trafficking and acidification, and mediates viral genome penetration into the cytoplasm to propagate the infection.
RAP1 (show RABGEF1 Proteins) promotes colorectal cell migration through the regulation of Vimentin and RAP1 (show RABGEF1 Proteins) may act as a potential target for the diagnosis and therapy of CRC (show CALR Proteins).
High vimentin expression is associated with Non Small-cell Lung Cancer.
data demonstrates that keratinocyte migration requires the interaction between vimentin and keratins at the -YRKLLEGEE- sequence at the helical 2B domain of vimentin
Immunocytochemistry for Vimentin detection in nuclei of IVF (show SCN5A Proteins) and NT bovine embryos
These results indicate that the inner mass differentiates dynamically in blastocysts, as reflected by the expression of vimentin; higher vimentin expression may reflect the higher developmental competence of embryos.
an intact vimentin intermediate filament network contributes to the maintenance of the chondrocyte phenotype
Knockdown of filamin A (show FLNA Proteins) or vimentin in normal cells profoundly suppresses apical extrusion of the neighbouring transformed cells.
vimentin knockout neurons were insensitive to the axonotrophic effects of Clostridium botulinum C3 exoenzyme
findings thus show that the inability to produce GFAP (show GFAP Proteins) and Vim affects normal retinal physiology and that the effect of IF deficiency on retinal cell survival differs, depending on the underlying pathologic condition
these findings identify a hereto-unappreciated role for serine-38 phosphorylated vimentin as an important determinant of myofibroblast sensitivity to Withaferin A.
Vimentin expression increased after traumatic brain injury and was positively correlated with edema and neurological impairments.
Annexin, lamin (show LMNA Proteins), and vimentin were identified as universal dystrophic markers
Astrocytes deficient of GFAP (show GFAP Proteins) and vimentin showed decreased Notch (show NOTCH1 Proteins) signal sending competence and altered expression of Notch (show NOTCH1 Proteins) signaling pathway-related genes
Absence of GFAP (show GFAP Proteins), or both GFAP (show GFAP Proteins) and vimentin, alters Alzheimer's disease-induced changes in gene expression profile of astrocytes, showing a compensation of the decrease of neuronal support genes and a trend for a higher inflammatory expression profile
Vimentin is not only a major organizing element of the intermediate filament network but is also involved in both binding and uptake of C3 exoenzyme.
Vimentin has a role in regulating activation of the NLRP3 (show NLRP3 Proteins) inflammasome
As the inner cell mass forms the epiblast, SSEA1 (show FUT4 Proteins) is lost and VIMENTIN is lost and re-expressed.
These observations indicate that vimentin serves as a putative receptor for Japanese encephalitis virus in porcine kidney cells.
Interaction of nucleocapsid protein of transmissible gastroenteritis virus with host vimentin is required for virus infection.
protein(s) that associated with RPTPbeta in response to IGF-I and IGFBP-2 in vascular smooth muscle cells
This study demonstrates that maternal VIM, as a genomic protector, is crucial for nuclear reprogramming in porcine cloned embryos.
Vim expression in corneal epithelium is found in a cell population composed of highly motile cells.
This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.
, vimentin 1
, class-III intermediate microfilament