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Human Vimentin Protein expressed in Wheat germ - ABIN1325010
Kim, Nakamura, Lee, Hong, Pérez-Sala, McCulloch: Regulation of cell adhesion to collagen via beta1 integrins is dependent on interactions of filamin A with vimentin and protein kinase C epsilon. in Experimental cell research 2010
This study evaluated the expression pattern of vimentin in testes of mature Arabian stallions and correlated its distribution with grade of seminiferous tubule impairment as indicated by a Johnsen score.
Vimentin- like transcript was expressed in both chordocytes and chordoblasts, whereas the elastin (show ELN Proteins)- like transcript was uniquely expressed in the chordoblasts lining the notochordal sheath.
The present study therefore indicated that IL-6 (show IL6 Proteins) promoted the process of EMT (show ITK Proteins) in HIBECs as characterized by increased migration and invasion of HIBECs and the typical changes in mRNA and protein expression of the EMT (show ITK Proteins) markers E-cadherin (show CDH1 Proteins) and vimentin.
Data show that over-expression of vimentin ameliorated cytotoxicity of gambogic acid (GA) in HeLa cells.
High vimentin and low beta4 integrin protein levels are associated with poor survival in oral squamous carcinoma patients.
PTTG2 induces psoriasis by regulating epidermal expression of vimentin and E-cadherin (show CDH1 Proteins).
On the basis of these results, we propose a model in which dynamic vimentin filaments target CARMIL2 to critical membrane-associated locations, where CARMIL2 regulates CP, and thus actin assembly, to create cell protrusions
These data suggest that the number of polyploid giant cancer cells and the EMT (show ITK Proteins)-related proteins E-cadherin (show CDH1 Proteins), N-cadherin (show CDH2 Proteins), and vimentin may be valuable biomarkers to assess metastasis in patients with breast cancer.
Vimentin Regulates Invasiveness and Is a Poor Prognostic Marker in Non-small Cell Lung Cancer
HtrA2 (show HTRA2 Proteins) under stress conditions induces vimentin cleavage in wild-type and SH-SY5Y cells transfected with APP (show APP Proteins) with the Alzheimer disease-associated Swedish mutation. Interplay between Omi/HtrA2 (show HTRA2 Proteins) and vimentin affects mitochondrial distribution in neurons.
AOC4P lncRNA acts as a hepatocellular carcinoma tumor suppressor by enhancing vimentin degradation and suppressing the epithelial-mesenchymal transition
Studied the link between VEGFR-1 (show FLT1 Proteins) and PKG (show PRKG1 Proteins)-1 in copper regression of cardiomyocyte hypertrophy.
Immunocytochemistry for Vimentin detection in nuclei of IVF (show SCN5A Proteins) and NT bovine embryos
These results indicate that the inner mass differentiates dynamically in blastocysts, as reflected by the expression of vimentin; higher vimentin expression may reflect the higher developmental competence of embryos.
an intact vimentin intermediate filament network contributes to the maintenance of the chondrocyte phenotype
Knockdown of filamin A (show FLNA Proteins) or vimentin in normal cells profoundly suppresses apical extrusion of the neighbouring transformed cells.
findings thus show that the inability to produce GFAP (show GFAP Proteins) and Vim affects normal retinal physiology and that the effect of IF deficiency on retinal cell survival differs, depending on the underlying pathologic condition
these findings identify a hereto-unappreciated role for serine-38 phosphorylated vimentin as an important determinant of myofibroblast sensitivity to Withaferin A.
Vimentin expression increased after traumatic brain injury and was positively correlated with edema and neurological impairments.
Annexin, lamin (show LMNA Proteins), and vimentin were identified as universal dystrophic markers
Astrocytes deficient of GFAP (show GFAP Proteins) and vimentin showed decreased Notch (show NOTCH1 Proteins) signal sending competence and altered expression of Notch (show NOTCH1 Proteins) signaling pathway-related genes
Absence of GFAP (show GFAP Proteins), or both GFAP (show GFAP Proteins) and vimentin, alters Alzheimer's disease-induced changes in gene expression profile of astrocytes, showing a compensation of the decrease of neuronal support genes and a trend for a higher inflammatory expression profile
Vimentin is not only a major organizing element of the intermediate filament network but is also involved in both binding and uptake of C3 exoenzyme.
Vimentin has a role in regulating activation of the NLRP3 (show NLRP3 Proteins) inflammasome
protein(s) that associated with RPTPbeta in response to IGF-I and IGFBP-2 in vascular smooth muscle cells
Data suggest MAP kinase (show MAPK1 Proteins)-interacting kinases (Mnk1 (show MKNK1 Proteins), Mnk2 (show MKNK2 Proteins)) regulate cell migration/wound healing, expression of Vim, stability of Vim, and binding of eIF4E (eukaryotic translation initiation factor 4E (show EIF4E Proteins))/Cyfip1 (cytoplasmic FMR1 interacting protein 1 (show CYFIP1 Proteins)).
Interaction of nucleocapsid protein of transmissible gastroenteritis virus with host vimentin is required for virus infection.
This study demonstrates that maternal VIM, as a genomic protector, is crucial for nuclear reprogramming in porcine cloned embryos.
These observations indicate that vimentin serves as a putative receptor for Japanese encephalitis virus in porcine kidney cells.
As the inner cell mass forms the epiblast, SSEA1 (show FUT4 Proteins) is lost and VIMENTIN is lost and re-expressed.
This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.
, vimentin 1
, class-III intermediate microfilament