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Browse our Haptoglobin Proteins (HP)

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Haptoglobin Proteins (HP)
On are 72 Haptoglobin (HP) Proteins from 13 different suppliers available. Additionally we are shipping Haptoglobin Antibodies (340) and Haptoglobin Kits (127) and many more products for this protein. A total of 549 Haptoglobin products are currently listed.
BP, HP, HP-1, HP2ALPHA2, HPA1S, HPR, wu:fb64e01, Zonulin
list all proteins Gene Name GeneID UniProt
HP 3240 P00738
HP 24464 P06866
HP 15439 Q61646

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Haptoglobin Proteins (HP) by Origin

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Top referenced Haptoglobin Proteins

  1. Human Haptoglobin Protein expressed in Human - ABIN491578 : Zapotoczna, Heilbronner, Speziale, Foster: Iron-regulated surface determinant (Isd) proteins of Staphylococcus lugdunensis. in Journal of bacteriology 2012 (PubMed)
    Show all 2 references for ABIN491578

More Proteins for Haptoglobin Interaction Partners

Human Haptoglobin (HP) interaction partners

  1. Our findings suggest that increased serum zonulin concentration, i.e., increased intestinal permeability, contributes to metabolic endotoxemia, systemic inflammation, and insulin (show INS Proteins) resistance in overweight pregnant women

  2. The present study demonstrated that the mRNA and protein expression levels of haptoglobin were increased in patients with psoriasis.

  3. SCC (show CYP11A1 Proteins)-specific HP peptide HP216 may have a role in lung squamous cell carcinoma and could be a serum biomarker

  4. Altered glycosylation, expression of serum haptoglobin and alpha-1-antitrypsin (show SERPINA1 Proteins) in chronic hepatitis C, hepatitis C induced liver cirrhosis and hepatocellular carcinoma patients.

  5. In addition to predicting the incidence of cardio-renal complications, HP 2-2 also increases susceptibility for cardio-renal mortality in type 1 diabetes.

  6. Findings suggest that the antioxidative and anti-inflammatory capacity of the Hp 2 (show DEFa3 Proteins) is inferior to that of the Hp 1 (show DEFA1 Proteins) allele.

  7. The ratio of the fucosylated peaks to their corresponding nonfucosylated forms shows that the fucosylated glycans from haptoglobin are upregulated in the case of hepatocellular carcinoma samples versus cirrhosis samples.

  8. The bifucosylated tetra-anntenary glycan of haptoglobin was upregulated in hepatocellular carcinoma patients of all etiologies.

  9. Ovarian cancer cells express both Hp and its receptor CCR2 but only after exposure to ascitic fluid, inducing moderated cell migration; results suggest that Hp-induced changes in the cell morphology, actin cytoskeleton structure, and migration ability of tumor cells, is possibly "preparing" these cells for the potential induction of the metastatic phenotype.

  10. Haptoglobin phenotype is unlikely to be an important modifier of cystic fibrosis (show S100A8 Proteins) phenotype.

Cow (Bovine) Haptoglobin (HP) interaction partners

  1. These data demonstrate that serum neutrophil haptoglobin-MMP 9 (show MMP9 Proteins) complexes appear sooner and decline more rapidly than other acute phase proteins.

  2. An increase in serum amyloid A or haptoglobin in dairy cows with abomasal displacementis not specific for inflammation or bacterial infection; increased levels of either may indicate the presence of hepatic lipidosis.

  3. Haptoglobin concentration may be a useful indicator for cows with postpartum reproductive disorders.

  4. Presence in the milk of the acute phase proteins (APP (show APP Proteins)), haptoglobin (Hp) and serum amyloid A to see the relationships in cow composite and bulk tank milk samples.

  5. Bovine granulocytes, isolated from peripheral blood of healthy cattle, contain abundant amounts of haptoglobin within the granules.

  6. This study suggests that neutrophils and epithelial cells may play an essential role in elevating milk haptoglobin (Hp) in addition to previous suggestions that Hp may be derived from mammary tissues and circulation.

Mouse (Murine) Haptoglobin (HP) interaction partners

  1. the interaction between haptoglobin genotype and vitamin E affects atherosclerotic plaque progression and stability

  2. Exogenous haptoglobin attenuated the HbA (show HBA-A1 Proteins)-induced HO-1 (show HMOX1 Proteins) expression in vitro and in mouse model of sickle cell disease.

  3. Suggest haptoglobin is an enhancer of inflammation after cardiac transplantation, contributing to graft rejection.

  4. Zonulin facilitates development of acute lung injury (ALI) both by enhancing albumin (show ALB Proteins) leak and complement activation as well as increased buildup of neutrophils and cytokines during development of ALI.

  5. Haptoglobin deficiency is associated with leakage-prone vessels via isolated VEGFA (show VEGFA Proteins) induction and/or suppressed Ang-1 (show ANGPT1 Proteins) expression, resulting in unbalanced VEGFalpha/Ang-1 (show ANGPT1 Proteins) transcription.

  6. the Hp2-2 protein is involved in aneurysm formation and that the Hp genotype may be a useful biomarker in predicting aneurysm progression

  7. Experimental models of colitis showed that haptoglobin has a protective role in inflammatory colitis

  8. these studies provide direct evidence that the increased oxidative stress in Hp 2-2 atherosclerotic plaques is due to hemoglobin derived iron.

  9. Synthetic PPAR gamma (show PPARG Proteins) ligands selectively activate PPAR gamma (show PPARG Proteins) bound to the haptoglobin gene promoter to arrest haptoglobin gene transcription.

  10. Hp may be regarded as a regulator of the Th1 (show HAND1 Proteins)/Th2 balance in both human and murine immune systems.

Pig (Porcine) Haptoglobin (HP) interaction partners

  1. crystal structure of the dimeric porcine haptoglobin-haemoglobin complex determined at 2.9 A resolution

  2. haptoglobin has a role in oxidative status in piglets undergoing weaning-induced stress

  3. This study suggested closer links between the release of haptoglobin, Pig-MAP and monocytes compared to the release of AGP, SAA (show SAA1 Proteins) and transthyretin (show TTR Proteins).

  4. The haptoglobin was down-regulated with SNPs

Horse (Equine) Haptoglobin (HP) interaction partners

  1. Surfactant protein D (show SFTPD Proteins) and haptoglobin serum concentrations could be a diagnostic aid for equine inflammatory airway disease.

Haptoglobin (HP) Protein Profile

Protein Summary

This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Haptoglobin (HP)

  • haptoglobin (HP)
  • haptoglobin (hp)
  • haptoglobin (Hp)
  • haptoglobin-like (LOC100067869)
  • BP protein
  • HP protein
  • HP-1 protein
  • HP2ALPHA2 protein
  • HPA1S protein
  • HPR protein
  • wu:fb64e01 protein
  • Zonulin protein

Protein level used designations for Haptoglobin Proteins (HP)

haptoglobin , HpL , binding peptide , haptoglobin alpha(1S)-beta , haptoglobin alpha(2FS)-beta , haptoglobin, alpha polypeptide , haptoglobin, beta polypeptide , zonulin , liver regeneration-related protein LRRG173 , haptoglobin-related protein , haptoglobin alpha 1S

454233 Pan troglodytes
706640 Macaca mulatta
566096 Danio rerio
3240 Homo sapiens
24464 Rattus norvegicus
280692 Bos taurus
100144610 Felis catus
15439 Mus musculus
479668 Canis lupus familiaris
397061 Sus scrofa
100008816 Oryctolagus cuniculus
100721435 Cavia porcellus
101102413 Ovis aries
101841186 Mesocricetus auratus
100173782 Pongo abelii
100067869 Equus caballus
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