6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 4 Proteins (PFKFB4)

Synthesis and degradation of fructose 2,6-bisphosphate.. Additionally we are shipping PFKFB4 Antibodies (44) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PFKFB4 5210 Q16877
PFKFB4 270198 Q6DTY7
PFKFB4 54283 P25114
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top PFKFB4 Proteins at antibodies-online.com

Showing 7 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 60 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 60 Days
Wheat germ Human GST tag 10 μg 11 to 12 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
Yeast Rat His tag   1 mg 60 to 71 Days
Yeast Cynomolgus His tag   1 mg 60 to 71 Days
Baculovirus infected Insect Cells Human GST tag   20 μg 1 to 2 Days

PFKFB4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
, ,
Mouse (Murine)

Rat (Rattus)

More Proteins for 6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 4 (PFKFB4) Interaction Partners

Xenopus laevis 6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 4 (PFKFB4) interaction partners

  1. These findings highlight novel and essential roles of PFKFB4 activity in later stages of neural crest (NC) development that are wired into the NC gene regulatory network.

Human 6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 4 (PFKFB4) interaction partners

  1. CD44ICD interacts with CREB and binds to the promoter region of PFKFB4, thereby regulating PFKFB4 transcription and expression.

  2. Epithelial and endothelial tyrosine kinase (Etk) interacts with 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 (PFKFB4) to promote small-cell lung cancer (SCLC) chemoresistance through regulation of autophagy.

  3. Currently available anti-melanoma therapeutic strategies may significantly benefit from agents targeting PFKFB4 activity.

  4. PFKFB4 enhances the invasiveness of breast cancer cells in vitro and in vivo by inducing HA production and PFKFB4-induced expression of HAS2 depends upon the activation of p38 signaling.

  5. findings suggest that the Warburg pathway enzyme PFKFB4 acts as a molecular fulcrum that couples sugar metabolism to transcriptional activation by stimulating SRC-3 to promote aggressive metastatic tumours

  6. Data show that PFKFB4 is the target gene of PPARgamma which modulates the transcriptional activity of its promoter.

  7. Our FD models could facilitate a better mechanistic understanding of FD and help develop effective therapeutics for FD and other fibrosis diseases.

  8. High PFKFB4 expression is associated with colon and lung cancer.

  9. This work has uncovered a novel function of the enzymes PFKFB3 and PFKFB4 in ovarian cancer cells during mitotic arrest

  10. HIF-1alpha transactivates hypoxia-responsive elements (HRE)-D of the promoter region of PFKFB4 in hypoxia condition.

  11. The expression of PFKFB3, PFKFB4, NAMPT, and TSPAN13 is strongly up-regulated in pediatric glioma.

  12. Inhibition of PFKFB4 suppresses glycolysis and proliferation of multiple human cancer cell lines.

  13. PFKFB4 suppresses oxidative stress and p62 accumulation, without which autophagy is stimulated likely as a ROS detoxification response.

  14. Data indicate that the PFKFB4 expressed in multiple transformed cells and tumors functions to synthesize F2,6BP.

  15. we found that the glycolytic enzyme PFKFB4 is essential for prostate cancer cell survival by maintaining the balance between the use of glucose for energy generation and the synthesis of antioxidants.

  16. PFKFB4 has an important role in the progression of non-muscle-invasive bladder cancer (

  17. PFKFB4 and HO-2 are expressed in a coordinated manner to maintain glucose homeostasis.

  18. Data suggest that molecular mechanism by which dihydrotestosterone induces Pfkfb4 (and thus glycolysis) during spermatogenesis involves stimulation of Sertoli cells to secrete FGF-2 (fibroblast growth factor 2); study uses recombinant human Pfkfb4.

  19. an essential role of PFKFB4 in the maintenance of brain cancer stem-like cells

  20. Sulforaphane is a potent inducer of apoptosis in hepatocellular carcinoma cells via PFKFB4-inhibition pathways.

Mouse (Murine) 6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 4 (PFKFB4) interaction partners

  1. Inhibition of PFKFB4 suppresses glycolysis and proliferation of multiple human cancer cell lines.

PFKFB4 Protein Profile

Protein Summary

Synthesis and degradation of fructose 2,6-bisphosphate.

Gene names and symbols associated with PFKFB4

  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 (pfkfb4)
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 S homeolog (pfkfb4.S)
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 (PFKFB4)
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4a (pfkfb4a)
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 (f264)
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 (Pfkfb4)
  • C230090D14 protein
  • MGC69186 protein
  • MGC81068 protein
  • PFKFB4 protein
  • zgc:123288 protein

Protein level used designations for PFKFB4

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 , 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 , 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4-like , 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-4 , 6PF-2-K/Fru-2,6-P2ase 4 , 6PF-2-K/Fru-2,6-P2ase testis-type isozyme , PFK/FBPase 4 , bifunctional enzyme with kinase and biphosphatase activities , 6PF-2-K/Fru-2,6-P2ASE testis-type isozyme

407880 Xenopus (Silurana) tropicalis
432000 Xenopus laevis
460346 Pan troglodytes
534928 Bos taurus
556190 Danio rerio
100195507 Salmo salar
100345242 Oryctolagus cuniculus
100560960 Anolis carolinensis
5210 Homo sapiens
270198 Mus musculus
54283 Rattus norvegicus
Selected quality suppliers for PFKFB4 Proteins (PFKFB4)
Did you look for something else?