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The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. Additionally we are shipping AKAP14 Antibodies (18) and AKAP14 Kits (1) and many more products for this protein.
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AKAP28 likely plays a role in the signaling necessary for efficient modulation of ciliary beat frequency
The authors identify and characterize the human AKAP14, also known as AKAP28, and demonstrate that recombinant AKAP14 co-purifies with the catalytic subunit of protein kinase A and that endogenous AKAP14 localizes to airway cilia.
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The protein anchors PKA in ciliary axonemes and, in this way, may play a role in regulating ciliary beat frequency. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
A kinase (PRKA) anchor protein 14 , A-kinase anchor protein 14 , A-kinase anchor protein 28 kDa , A-kinase anchoring protein 28 , AKAP 28 , AKAP-14 , protein kinase A-anchoring protein 14 , TAKAP-1.2 , Testis-specific A-kinase-anchoring-protein , testis-specific A-kinase-anchoring protein TAKAP-80