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ADAMTS15 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Additionally we are shipping ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 15 Antibodies (25) and ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 15 Proteins (3) and many more products for this protein.
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spiking parvalbumin interneurons enwrapped in the perineuronal net express the metallopeptidases Adamts15 in mice.
Results show that ADAMTS15 and ADAMTS4 not only exhibit unique cellular expression patterns in the brain but their developmental upregulation by these cell types coincides with critical aspects of neural development
these data suggest a role for ADAMTS15 in a wide range of biological processes that are potentially mediated through the processing of versican.
ADAMTS4 and ADAMTS15 were upregulated in symptomatic uterine leiomyomas.
ADAMTS15 expression is significantly upregulated in human masticatory mucosa during wound healing
ADAMTS15 is a candidate gene for intracranial aneurysms
ADAMTS-15 has multiple actions on tumor pathophysiology including modulation of cell-extracellular matrix interactions, which likely involve syndecan-4.
Versican processing by ADAMTS5 and ADAMTS15 contribute to muscle fiber formation.
ADAMTS-15 but not ADAMTS-1 expression was downregulated by androgen in LNCaP prostate cancer cells, possibly through androgen response elements associated with the gene
negative effect of TGFbeta1 on ADAMTS-1, -5, -9, and -15 coupled with increases in their inhibitor, TIMP-3 may aid the accumulation of versican in the stromal compartment of the prostate in BPH and prostate cancer
ADAMTS8 and ADAMTS15 have emerged as novel predictors of survival in patients with breast carcinoma
ADAMTS15 may be target of inactivating mutations in human cancer.
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the proteins encoded by ADAMTS1 and ADAMTS8.
A disintegrin and metalloproteinase with thrombospondin motifs 15
, ADAM-TS 15
, a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 15
, a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 15, preproprotein
, metalloprotease disintegrin 15 with thrombospondin domains
, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 15