anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 2 (Adamts2) Antibodies

Adamts2 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Additionally we are shipping Adamts2 Kits (17) and Adamts2 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Adamts2 216725 Q8C9W3
Adamts2 9509 O95450
Adamts2 287899  
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Top anti-Adamts2 Antibodies at antibodies-online.com

Showing 10 out of 48 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB Western blot analysis of ADAMTS2 expression in A431 (A), MCF7 (B), SP2/0 (C), H9C2 (D) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Details
Mouse Rabbit Un-conjugated ICC, IHC, WB Figure. DAB staining on IHC-P; Samples: Mouse Brain Tissue. 100 μg 13 to 16 Days
$360.00
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, WB Western blot analysis of ADAMTS2 using COLO205 whole cell lysates ABIN6279089 staining HepG2 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibod 100 μL 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated IHC (fro), IHC (p), WB Anti-ADAMTS2 antibody, IHC(F) IHC(F): Rat Trachea Tissue Anti-ADAMTS2 antibody, IHC(P) IHC(P): Rat Cardiac Muscle Tissue 100 μg 4 to 6 Days
$280.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL 11 to 14 Days
$419.83
Details
Cow Rabbit Un-conjugated ICC, IHC, WB 100 μg 15 to 18 Days
$420.00
Details
Cow Mouse Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg 13 to 16 Days
$308.00
Details
Bat Rabbit Un-conjugated IHC, IHC (fro), IHC (p), WB   100 μg 11 to 14 Days
$537.17
Details
Human Rabbit Un-conjugated IHC, WB   100 μg 11 to 16 Days
$572.00
Details
Mouse Rabbit Un-conjugated WB   100 μL 11 to 14 Days
$405.17
Details

More Antibodies against Adamts2 Interaction Partners

Mouse (Murine) ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 2 (Adamts2) interaction partners

  1. Mice lacking Adamts2 and Adamts14 develop spontaneous atopic dermatitis due to immune dysregulation.

  2. ADAMTS2 plays a critical role in cardiac hypertrophy induced by pressure overload in mouse model.

  3. Data show that the high titer and specific rabbit anti-ADAMTS2 antibody has been prepared successfully.

  4. There is no significant genotype effect of ADAMTS2 on age, height, weight, BMI or sex on risk of Achilles tendon pathology.

  5. Data show that ADAMTS-2 is able to reduce proliferation of endothelial cells, and to induce their retraction and detachment from the substrate resulting in apoptosis.

  6. The extent of liver fibrosis is reduced in ADAMTS2-deficient mice in comparison with their wild type littermates.

  7. Data show thatincreased mRNA of Lamb3 and Adamts2 and enhanced activities of metalloproteinases MMP1, 2 and 7 in transgenic mice expressing the HLA-DQ8.

Human ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 2 (Adamts2) interaction partners

  1. ADAMTS-2, collagen type-1, TIMP-3 and papilin levels of the uterosacral ligament play essential roles in the etiopathogenesis of pelvic organ prolapse among postmenopausal women without stress urinary incontinence.

  2. We identified three novel homozygous loss-of-function mutations (c.2927_2928delCT, p.(Pro976Argfs*42); c.669_670dupG, p.(Pro224Argfs*24); and c.2751-2A>T) and one compound heterozygous mutation (c.2T>C, p.? and c.884_887delTGAA, p.(Met295Thrfs26*)) in ADAMTS2 in five patients from four unrelated families

  3. Data indicate that ADAMTS2 and 3 cleave the amino-propeptide of fibrillar collagens and regulate blood vessels homeostasis and lymphangiogenesis. Also, ADAMTS2 deficiency leads to the dermatosparactic type of Ehlers-Danlos syndrome. [review]

  4. IL-1a is a strong positive regulator of ADAMTS-2 and ADAMTS-3 expression.

  5. ADAMTS2 was significantly overexpressed in Fibrous dysplasia (FD) tissues, but rarely expressed in normal bone tissues, suggesting that ADAMTS2 could be a potential biomarker for FD

  6. Pathway inhibition studies revealed that ADAMTS-2 upregulation by IL-6 was mediated by JNK pathway.

  7. ADAMTS-2, -3, and -13 expression, but not that of ADAMTS-14, are increased in plaques causing AMI compared those associated with stable angina.

  8. Data show that ADAMTS-2 is able to reduce proliferation of endothelial cells, and to induce their retraction and detachment from the substrate resulting in apoptosis.

  9. Determination of the processing, activity and cleavage specificity of the bovine ADAMTS2 protein.

  10. when conditioned media of TSP2-transfectants were added to cultures of bovine pulmonary microvascular endothelial cells (BPMEC), the BPMEC proliferation was significantly inhibited; suggesting that human TSP2 is a potential inhibitor of angiogenesis

  11. Although exons 3-5 or 14-16 encode protein domains that have not been recognized as crucial for ADAMTS-2 activity, the aminoprocollagen processing was strongly impaired, providing evidence for the requirement of these domains for proper enzyme function

Cow (Bovine) ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 2 (Adamts2) interaction partners

  1. specific ADAMTS-2 domains cleave the aminopropeptide of fibrillar procollagens types I-III and V

Adamts2 Antigen Profile

Protein Summary

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene excises the N-propeptide of type I, type II and type V procollagens. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with Adamts2

  • a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2 (Adamts2) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif 2 (ADAMTS2) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif, 2 (Adamts2) antibody
  • ADAM-TS2 antibody
  • ADAMTS-2 antibody
  • ADAMTS-3 antibody
  • hPCPNI antibody
  • mKIAA4060 antibody
  • NPI antibody
  • PC I-NP antibody
  • PCI-NP antibody
  • PCINP antibody
  • PCPNI antibody
  • PNPI antibody
  • RGD1565950 antibody

Protein level used designations for Adamts2

A disintegrin and metalloproteinase with thrombospondin motifs 2 , ADAM-TS 2 , PC I-NP , a disintegrin and metalloproteinase with thrombospondin repeats , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 2 , procollagen I/II amino propeptide-processing enzyme , procollagen N-endopeptidase , procollagen N-proteinase , procollagen I N-proteinase , a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2 , ADAM-TS2 , ADAMTS-2 , pNPI

GENE ID SPECIES
216725 Mus musculus
9509 Homo sapiens
287899 Rattus norvegicus
416291 Gallus gallus
481453 Canis lupus familiaris
282401 Bos taurus
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