ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 3 Proteins (ADAMTS3)

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene is the major procollagen II N-propeptidase. A deficiency of this protein may be responsible for dermatosparaxis, a genetic defect of connective tissues.

• ADAM metallopeptidase with thrombospondin type 1 motif 3 (ADAMTS3)
• ADAM metallopeptidase with thrombospondin type 1, motif 3 (Adamts3)
• a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3 (Adamts3)
• ADAM metallopeptidase with thrombospondin type 1 motif 3 (Adamts3)

• 1100001H14Rik protein
• 6330442E02Rik protein
• ADAMTS-4 protein

A disintegrin and metalloproteinase with thrombospondin motifs 3 , ADAM-TS 3 , ADAM-TS3 , ADAMTS-3 , PC II-NP , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 3 , procollagen II N-proteinase , procollagen II amino propeptide-processing enzyme , zinc metalloendopeptidase , ADAM metallopeptidase with thrombospondin type 1 motif, 3