More product categories related to ADAM Metallopeptidase with thrombospondin Type 1 Motif, 17 ELISA Kit
More ELISA Kits for ADAM Metallopeptidase with thrombospondin Type 1 Motif, 17 Interaction Partners
Mouse (Murine) ADAM Metallopeptidase with thrombospondin Type 1 Motif, 17 (ADAMTS17) interaction partners
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Adamts17 is involved in skeletal formation by modulating BMP-Smad1/5/8 pathway, possibly through inhibiting the incorporation of fibrillin-2 into microfibrils. Delayed terminal differentiation of Adamts17-/- chondrocytes, observed both in primary chondrocyte and primordial metatarsal culture.
Human ADAM Metallopeptidase with thrombospondin Type 1 Motif, 17 (ADAMTS17) interaction partners
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A novel nonsense mutation c.1051 A > T in ADAMTS17 had been identified caused autosomal recessive WMS in the Chinese family.
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Secretion of ADAMTS17 requires O-fucosylation. ADAMTS17 binds fibrillin-2 but not fibrillin-1 and does not cleave either. ADAMTS17 regulates fibrillin isoform composition of microfibrils in the eye.
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higher Adamts17 expression is found in several human cancer cell subtypes, especially in breast ductal carcinoma and there is an inverse correlation between higher Adamts17 expression and patients' survival.
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A mutation in WMS-like gene ADAMTS17 also causes WMS.
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Endothelial protease nexin-1 is a novel regulator of A disintegrin and metalloproteinase 17 maturation and endothelial protein C receptor shedding via furin inhibition.
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Recessive ADAMTS17 mutations are a recurrent cause of isolated spherophakia with short stature.
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ADAMTS17 is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells.
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Homozygous mutation in ADAMTS17 causes lenticular myopia, ectopia lentis, glaucoma, spheropakia, and short stature.
ADAM Metallopeptidase with thrombospondin Type 1 Motif, 17 (ADAMTS17) Antigen Profile
Antigen Summary
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the protein encoded by ADAMTS19, another family member. The function of this protein has not been determined.
Gene names and symbols associated with ADAMTS17
- a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17 (Adamts17) antibody
- ADAM metallopeptidase with thrombospondin type 1 motif 17 (ADAMTS17) antibody
- ADAM metallopeptidase with thrombospondin type 1 motif, 17 (Adamts17) antibody
- ADAM metallopeptidase with thrombospondin type 1 motif 17 (adamts17) antibody
- ADAM metallopeptidase with thrombospondin type 1 motif, 17 (ADAMTS17) antibody
- ADAMTS17 antibody
- AU023434 antibody
Protein level used designations for ADAMTS17
ADAM metallopeptidase with thrombospondin type 1 motif, 17 , disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 17 , A disintegrin and metalloproteinase with thrombospondin motifs 17 , ADAM-TS 17 , ADAM-TS17 , ADAMTS-17 , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 17 , A disintegrin and metalloproteinase with thrombospondin motifs 17-like
GENE ID | SPECIES |
---|---|
233332 | Mus musculus |
170691 | Homo sapiens |
293004 | Rattus norvegicus |
415515 | Gallus gallus |
453682 | Pan troglodytes |
488708 | Canis lupus familiaris |
538131 | Bos taurus |
693447 | Macaca mulatta |
100020525 | Monodelphis domestica |
100339274 | Oryctolagus cuniculus |
100380150 | Xenopus (Silurana) tropicalis |
100467246 | Ailuropoda melanoleuca |
100155073 | Sus scrofa |
100546307 | Meleagris gallopavo |
100554641 | Anolis carolinensis |
101110624 | Ovis aries |
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