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arfgap2 encodes a zinc-finger-containing GTPase-activating protein for ADP ribosylation factor 1 (ARF1), a small GTPase that plays a role in coatomer-mediated vesicular trafficking. Additionally we are shipping arfgap2 Antibodies (42) and arfgap2 Proteins (4) and many more products for this protein.
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analysis of the distinct role of subcomplexes of the COPI coat in the regulation of ArfGAP2 activity
ARFGAP2 and ARFGAP3 are essential for COPI coat assembly on the Golgi membrane of living cells.
human ARFGAP2 and ARFGAP3 are associated with COP-I-coated vesicles and function in COP I traffic
Differential roles of ArfGAP1, ArfGAP2, and ArfGAP3 in COPI trafficking
ArfGAP1, ArfGAP2, and ArfGAP3 have overlapping roles in regulating COPI function in Golgi-to-ER retrograde transport.
This gene encodes a zinc-finger-containing GTPase-activating protein for ADP ribosylation factor 1 (ARF1), a small GTPase that plays a role in coatomer-mediated vesicular trafficking. This gene product stimulates the hydrolysis of ARF1-bound GTP, which may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes. It may regulate the retrograde transport from the Golgi complex to the endoplasmic reticulum. Expression of this gene has been shown to be controlled by inhibitor of DNA binding 1 (Id1). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene was identified on chromosome 6.
ADP-ribosylation factor GTPase activating protein 2
, zinc finger protein 289, ID1 regulated
, ADP-ribosylation factor GTPase-activating protein 2
, ARF GAP 2
, GTPase-activating protein ZNF289
, zinc finger protein 289
, ADP-ribosylation factor GTPase-activating protein 2-like