anti-AE Binding Protein 1 (AEBP1) Antibodies

The adipocyte enhancer binding protein 1 is a transcriptional repressor with carboxypeptidase (CP) activity. Additionally we are shipping AEBP1 Kits (15) and AEBP1 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
AEBP1 165 Q8IUX7
AEBP1 11568 Q640N1
AEBP1 305494 A2RUV9
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Top anti-AEBP1 Antibodies at antibodies-online.com

Showing 10 out of 42 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB Human Intestine Human Spermatophore 100 μL Log in to see 2 to 3 Days
$319.00
Details
Human Rabbit Un-conjugated WB AEBP1 Antibody (Center)  western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the AEBP1 antibody detected the AEBP1 protein (arrow). AEBP1 Antibody (Center)  western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the AEBP1 antibody detected the AEBP1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$385.00
Details
Bat Rabbit Un-conjugated IHC, IHC (p), WB 100 μL Log in to see 11 to 14 Days
$581.17
Details
Human Rabbit Un-conjugated EIA, WB AEBP1 Antibody (Center) western blot analysis in 293 cell line lysates (35 µg/lane).This demonstrates the AEBP1 antibody detected the AEBP1 protein (arrow). AEBP1 Antibody (Center) western blot analysis in mouse lung tissue lysates (35µg/lane).This demonstrates the AEBP1 antibody detected the AEBP1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Human Mouse Un-conjugated ELISA, IHC, IHC (p), WB 100 μg Log in to see 11 to 14 Days
$537.17
Details
Human Mouse Un-conjugated CyTOF, FACS Detection of ACLP in HASMC Human Cells by Flow Cytometry. HASMC human human aortic smooth muscle cells was stained with Human ACLP Monoclonal Antibody. To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with saponin. 100 μg Log in to see 8 to 9 Days
$238.43
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of AEBP1 expression in HEK293 cells ,The lane on the left is treated with the antigen-specific peptide. 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 100 μL Log in to see 2 to 3 Days
$446.88
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to AEBP1 on formalin-fixed paraffin-embedded human adrenal gland. [antibody concentration 3 ug/ml] Detection limit for recombinant GST tagged AEBP1 is approximately 0.3ng/ml as a capture antibody. 100 μg Log in to see 11 to 12 Days
$364.00
Details
Human Rabbit Un-conjugated ELISA, IHC 200 μL Log in to see 12 to 14 Days
$438.90
Details

Top referenced anti-AEBP1 Antibodies

  1. Cow (Bovine) Polyclonal AEBP1 Primary Antibody for IHC, WB - ABIN2777370 : Kim, Gieske, Trudgen, Hudgins-Spivey, Kim, Krust, Chambon, Jeong, Blalock, Ko: Identification of estradiol/ER?-regulated genes in the mouse pituitary. in The Journal of endocrinology 2011 (PubMed)

More Antibodies against AEBP1 Interaction Partners

Human AE Binding Protein 1 (AEBP1) interaction partners

  1. These studies support the conclusion that bi-allelic pathogenic variants in AEBP1 are the cause of this autosomal-recessive Ehlers-Danlos Syndrome subtype.

  2. Studies identify ACLP as a stromal derived mediator of adipose progenitor differentiation that may limit adipocyte expansion during white adipose tissue fibrosis.

  3. AEBP1 protein is expressed in the pyramidal neurons of human central nervous system and increased in neurons and glial cells of hippocampi and parahippocampal cortices, correlating with the progression of Alzheimer's disease.

  4. ACLP stimulates the fibroblast-to-myofibroblast transition by promoting SMA expression via TGFbeta signaling and promoting collagen expression through a TGFbeta receptor-independent pathway.

  5. There is no statistically significant differences in the frequency of variants in AEBP1 among the gastroschisis case group compared to a Caucasian control group.

  6. Most ACLP knockout mice die perinatally due to abdominal issues.

  7. Both cellular proliferation and survival were affected in AEBP1-silenced U87MG and U138MG cell lines and a significant percentage of these cells were directed towards apoptosis.

  8. This review focuses on the recently reported regulatory functions that adipocyte enhancer-binding protein 1 (AEBP1) exerts on PPARgamma1 and LXRalpha transcriptional activity in the context of macrophage cholesterol homeostasis and inflammation.

  9. Transgenic overexpression of AEBP1 during adipogenesis coupled with a high-fat diet results in massive obesity in female transgenic mice via adipocyte hyperplasia.

  10. ACLP and its discoidin-like domain may be novel targets for anti-myofibroblast-based therapies for the treatment of pulmonary fibrosis.

Mouse (Murine) AE Binding Protein 1 (AEBP1) interaction partners

  1. ACLP stimulates the fibroblast-to-myofibroblast transition by promoting SMA expression via TGFbeta signaling and promoting collagen expression through a TGFbeta receptor-independent pathway.

  2. Stromal adipocyte enhancer-binding protein (AEBP1) promotes mammary epithelial cell hyperplasia via proinflammatory and hedgehog signaling

  3. Data suggest that macrophage AEBP1 plays critical regulatory roles in atherogenesis, and it may serve as a potential therapeutic target for the prevention or treatment of atherosclerosis.

  4. Results describe the pathophysiological features of gastroschisis in aortic carboxypeptidase-like protein knockout mice and to characterize the neuromuscular development of the eviscerated intestine.

  5. MAPK regulates the transcriptional activity of AEBP1 by a novel dual mechanism, in which MAPK interaction enhances and subsequent phosphorylation decreases the DNA-binding ability of AEBP1

  6. Developmental expression pattern is consistent with a regulatory or structural role in the abdominal wall, vasculature, and dermis.

  7. AEBP1 plays critical regulatory roles in macrophage cholesterol homeostasis, foam cell formation, and proinflammation.

  8. NF-kappaB activity is modulated by means of protein-protein interaction involving AEBP1 and IkappaBalpha.

  9. AEBP1 negatively regulates adipose tissue PTEN levels and has a key functional role in modulation of in vivo adiposity.

  10. Adipocyte enhancer-binding protein 1 (AEBP1) is up-regulated during monocyte differentiation.

  11. ACLP and its discoidin-like domain may be novel targets for anti-myofibroblast-based therapies for the treatment of pulmonary fibrosis.

AEBP1 Antigen Profile

Protein Summary

The adipocyte enhancer binding protein 1 is a transcriptional repressor with carboxypeptidase (CP) activity. This protein binds to a regulatory sequence, adipocyte enhancer 1 (AE-1), located in the proximal promoter region of the adipose P2 (aP2) gene, which encodes the adipocyte fatty-acid binding protein. It is characterized as a member of the regulatory B-like CP family. This protein seems to be activated by a novel mechanism, whereby the direct binding of DNA enhances its protease activity. Adipocyte-enhancer binding protein 1 may play a role in differentiated vascular smooth muscle cells.

Gene names and symbols associated with AEBP1

  • AE binding protein 1 (Closa_4071) antibody
  • AE binding protein 1 (AEBP1) antibody
  • AE binding protein 1 (Aebp1) antibody
  • ACLP antibody

Protein level used designations for AEBP1

AE binding protein 1 , adipocyte enhancer-binding protein 1 , aortic carboxypeptidase-like protein , AE-binding protein 1

GENE ID SPECIES
9509393 Clostridium saccharolyticum WM1
165 Homo sapiens
733628 Sus scrofa
11568 Mus musculus
305494 Rattus norvegicus
317693 Bos taurus
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