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Members of the ARID protein family, including ARID5A, have diverse functions but all appear to play important roles in development, tissue-specific gene expression, and regulation of cell growth (Patsialou et al., 2005. Additionally we are shipping AT Rich Interactive Domain 5A (MRF1-Like) Proteins (2) and many more products for this protein.
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AT-rich-interactive domain-containing protein 5A functions as a negative regulator of retinoic acid receptor (show RARA Antibodies)-related orphan nuclear receptor (show ESRRB Antibodies) gammat-induced Th17 cell differentiation.
High Arid5a expression is associated with inflammation.
Arid5a deficiency resulted in decreased levels of IFN-gamma under Th1 cell conditions, in which T-box expressed in T cells (T-bet) mRNA expression was inhibited.
data showed that regulation of Arid5a by NF-kappaB (show NFKB1 Antibodies) and MAPK (show MAPK1 Antibodies) signaling is required to maintain the balance of IL-6 (show IL6 Antibodies) mRNA expression
this study shows that Arid5a-deficient mice were highly refractory to bleomycin-induced lung injury
T cell-intrinsic role of Arid5a on fate decisions of naive CD4 (show CD4 Antibodies)(+)T cells through selective stabilization of Stat3 (show STAT3 Antibodies) mRNA.
Arid5a controls IL-6 (show IL6 Antibodies) mRNA stability, which contributes to elevation of IL-6 (show IL6 Antibodies) level in vivo.
AT-rich interactive domain-containing protein 5a (Arid5a) cooperates with Sox9 (show SOX9 Antibodies) to stimulate chondrocyte-specific transcription.
Members of the ARID protein family, including ARID5A, have diverse functions but all appear to play important roles in development, tissue-specific gene expression, and regulation of cell growth (Patsialou et al., 2005
AT rich interactive domain 5A (MRF1-like)
, AT-rich interactive domain-containing protein 5A-like
, AT-rich interactive domain-containing protein 5A
, ARID domain-containing protein 5A
, modulator recognition factor 1
, modulator recognition factor I
, AT rich interactive domain 5A (Mrf1 like)