anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 2 (ABCA2) Antibodies

The membrane-associated protein encoded by ABCA2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ABCA2 Proteins (3) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ABCA2 20 Q9BZC7
ABCA2 11305  
ABCA2 79248 Q9ESR9
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Top anti-ABCA2 Antibodies at antibodies-online.com

Showing 10 out of 85 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB Host:  Rabbit  Target Name:  ABCA2  Sample Type:  Jurkat Whole Cell lysates  Antibody Dilution:  1.0ug/ml 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), IP, IHC Immunohistochemistry-Paraffin: ABC2 Antibody [ABIN2616758] - FFPE section of human thyroid carcinoma. Antibody: Affinity purified rabbit anti-ABC2 used at a dilution of 1:250. Detection: DAB staining using Immunohistochemistry Accessory Kit 100 μL Log in to see 7 to 9 Days
$556.31
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
$242.88
Details
Dog Goat Un-conjugated ELISA, IHC, IHC (p) Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-ABCA2 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated WB Western Blot: ABC2 Antibody [NBP1-56876] - 721_B cell lysate, concentration 0.2-1 ug/ml. Western Blot: ABC2 Antibody [NBP1-56876] - Human Fetal Heart, Antibody Dilution: 1.0 ug/ml. 100 μL Log in to see 8 to 11 Days
$485.88
Details
Human Rabbit Un-conjugated IP Immunoprecipitation: ABCA2 Antibody [NBP1-30453] - Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from 293T cells. Antibodies: Affinity purified rabbit anti-ABCA2 antibodyNBP1-30453 used for IP at 10 mcg/mg lysate. ABCA2 was also immunoprecipitated by rabbit anti-ABCA2 antibodyNBP1-30452, which recognizes an upstream epitope. 100 μL Log in to see 7 to 9 Days
$533.31
Details
Human Rabbit Un-conjugated IP, WB Western Blot: ABCA2 Antibody [NBP1-30452] - Whole cell lysate from 293T cells. ABCA2 was also immunoprecipitated by rabbit anti-ABCA2 antibody NBP1-30453. 100 μL Log in to see 7 to 9 Days
$533.31
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: ABC2 Antibody [NBP1-87918] - Staining of human cell line U-251MG shows positivity in nucleus but not nucleoli. Immunohistochemistry-Paraffin: ABC2 Antibody [NBP1-87918] - Staining of human small intestine shows strong positivity in goblet cells. 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Goat Un-conjugated ELISA   0.1 mg Log in to see 7 to 9 Days
$373.75
Details
Mouse Rat PE FACS   100 Tests Log in to see 7 to 9 Days
$683.83
Details

ABCA2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ABCA2 Antibodies

  1. Polyclonal ABCA2 Primary Antibody for ELISA, WB - ABIN539709 : Macé, Cousin, Ricard, Génin, Spanakis, Lafargue-Soubigou, Génin, Fournel, Roche, Haussy, Massey, Soubigou, Bréfort, Benoit, Brice, Campion, Hollis, Pradier, Benavides, Deleuze: ABCA2 is a strong genetic risk factor for early-onset Alzheimer's disease. in Neurobiology of disease 2005 (PubMed)

More Antibodies against ABCA2 Interaction Partners

Human ATP-Binding Cassette, Sub-Family A (ABC1), Member 2 (ABCA2) interaction partners

  1. The analyses results suggested ABCA2 mRNA expression was upregulated significantly in AD compared with controls in all datasets.

  2. Our findings indicate a considerable and direct relationship between mRNA expression levels of ABCA2, ABCA3 (show ABCA3 Antibodies), MDR1 (show TBC1D9 Antibodies), and MRP1 (show MDM4 Antibodies) genes and positive minimal residual disease (MRD) measured after one year of treatment.

  3. Down-regulation of the ATP-binding cassette transporter 2 (Abca2) reduces amyloid-beta production by altering Nicastrin (show NCSTN Antibodies) maturation and intracellular localization.

  4. SLC2A1/GLUT1 (show SLC2A1 Antibodies), SLC1A3/EAAT1 (show SLC1A3 Antibodies), and SLC1A2/EAAT2 (show SLC1A2 Antibodies) were the main SLC (show CCL21 Antibodies) proteins whereas ABCG2/BCRP, ABCB1/MDR1 (show ABCB4 Antibodies), ABCA2 and ABCA8 (show ABCA8 Antibodies) were the main ABC (show ABCB6 Antibodies) quantified in isolated brain microvessels

  5. A possible biochemical mechanism links ABCA2 expression, amyloid precursor protein (show APP Antibodies) processing, and Alzheimer's disease.

  6. we demonstrate that ABCA2-deficiency inhibits prostate tumor metastasis in vivo and decreases chemotactic potential of cells

  7. roles for this largest known ABC (show ABCB6 Antibodies) protein in neural transmembrane lipid export

  8. Reciprocal regulation of expression of the ABCA2 promoter by the early growth response-1 (show EGR1 Antibodies) and Sp-family transcription factors.

  9. It is likely that expression of ABCA2 by two independent promoters constitutes locus of regulation controlling expression of the protein to meet requirements in different tissues.

  10. Increased expression of ABCA2 may be causally linked with altered expression of genes associated with the pathogenesis of Alzheimer disease.

Mouse (Murine) ATP-Binding Cassette, Sub-Family A (ABC1), Member 2 (ABCA2) interaction partners

  1. Study suggests that ABCA2 modulation of sphingolipid metabolism activates a signaling pathway that regulates amyloid precursor protein (show APP Antibodies) transcription

  2. control of ABCA2 expression level may be a key locus of regulation for esterification of plasma membrane-derived cholesterol through modulation of sphingolipid metabolism.

  3. Data from knockout mice suggest that Abca2 functions in penile erection; Abca2 knockout mice are more susceptible to estrogen-induced convulsions than wildtype mice; Abca2 appears to be involved in biotransformation of therapeutic estrogens.

  4. Lack of ABCA2 generates abnormalities in intracellular lipid distribution/trafficking in macrophages, increasing susceptibility to apoptosis in response to oxidized lipids and reduced atherosclerotic lesion development in LDL receptor (show LDLR Antibodies) knockout mice.

  5. The ATP-binding cassette transporter-2 (ABCA2) is a key regulator of cholesterol homeostasis and low-density lipoprotein receptor (show LDLR Antibodies) metabolism in neuronal cells.

  6. Down-regulation of the ATP-binding cassette transporter 2 (Abca2) reduces amyloid-beta production by altering Nicastrin (show NCSTN Antibodies) maturation and intracellular localization.

  7. ABC-me (show ABCB10 Antibodies) is a novel gene that determines the ability to tolerate cardiac ischemia/reperfusion.

  8. ABCA2 has a role in myelin compaction in spinal cord and cerebrum, and in phenotypic tremor

  9. ABCA2 is expressed in non-myelin-forming as well as in myelin-forming Schwann cells. ABCA2 may be involved in transport of a substance associated with cellular maturation rather than initial myelin formation in both types of Schwann cells.

  10. ABCA2 is involved in the intracellular metabolism of sphingolipids in the brain, particularly SM and gangliosides in oligodendrocytes and certain neurons.

ABCA2 Antigen Profile

Protein Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is highly expressed in brain tissue and may play a role in macrophage lipid metabolism and neural development. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ABCA2

  • ATP binding cassette subfamily A member 2 (ABCA2) antibody
  • ATP-binding cassette, sub-family A (ABC1), member 2 (Abca2) antibody
  • ATP binding cassette subfamily A member 2 (Abca2) antibody
  • ATP binding cassette subfamily A member 2 (abca2) antibody
  • ATP-binding cassette, sub-family A (ABC1), member 2 (abca2) antibody
  • Abc2 antibody
  • AI413825 antibody
  • D2H0S1474E antibody
  • mKIAA1062 antibody
  • si:dkey-266h7.1 antibody

Protein level used designations for ABCA2

ATP-binding cassette 2 , ATP-binding cassette sub-family A member 2 , ATP-binding cassette transporter 2 , ATP-binding cassette, sub-family A, member 2 , ATP-binding cassette, sub-family A (ABC1), member 2 , ATP-binding cassette sub-family A member 2-like

GENE ID SPECIES
20 Homo sapiens
11305 Mus musculus
79248 Rattus norvegicus
426955 Gallus gallus
480669 Canis lupus familiaris
100017432 Monodelphis domestica
100067889 Equus caballus
100231140 Taeniopygia guttata
100299651 Bos taurus
100498548 Xenopus (Silurana) tropicalis
100731855 Cavia porcellus
100006090 Danio rerio
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