anti-Acetyl LDL Receptor (SCARF1) Antibodies

Human Acetyl LDL Receptor (SCARF1) interaction partners

1. SCARF-1 promotes adhesion of CD4(+) T cells to human hepatic sinusoidal endothelium under conditions of shear stress

2. Scavenger receptor SREC-I promotes double stranded RNA-mediated TLR3 activation in human monocytes

3. These studies in addition to our earlier findings showed SREC-I to play a primary role in chaperone-associated antigen uptake both through cross priming of MHC class I molecules and entry into the class II pathway.

4. In several assay systems this type F-scavenger receptor, termed SREC-I, bound to cell wall techoic acid in a charge dependent manner and mediated adhesion to nasal epithelial cells in vitro.

5. GP2 is a binding partner of the scavenger receptor expressed on endothelial cells I (SREC-I) but not of SR-AI and SR-BI. Dendritic cells express SREC-I and also bind and internalize GP2.

6. Characterization of the gene and its regulation by a novel transcription factor, endothelial zinc protein-2

7. SRECI binds to SRECII and has a similar tissue distribution pattern

Mouse (Murine) Acetyl LDL Receptor (SCARF1) interaction partners

1. SREC-I became associated with TLR4 on binding bacterial lipopolysaccharides in RAW 264.7.

2. The scavenger receptor SCARF1 mediates the clearance of apoptotic cells and prevents autoimmunity.

3. SREC-I mediated internalization of Hsp90-ovalbumin polypeptide complexes through an endocytic pathway known as the glycosylphosphatidylinositol-anchored protein-enriched early endosomal compartment to recycling endosomes.

4. interaction of SREC-I and advillin are involved in the development of dorsal root ganglion neurons by inducing the described morphological changes.

5. Our system may be useful for the elucidation of the mechanism of morphological maturation of neuronal cells such as dorsal root ganglion neurons that express SREC-I during early development.

6. CED-1/SCARF1 and C03F11.3/CD36 are beta-glucan binding receptors and define an evolutionarily conserved pathway for the innate sensing of fungal pathogens.