anti-Achalasia, Adrenocortical Insufficiency, Alacrimia (AAAS) Antibodies

The protein encoded by AAAS is a member of the WD-repeat family of regulatory proteins and may be involved in normal development of the peripheral and central nervous system. Additionally we are shipping Adracalin Proteins (5) and Adracalin Kits (4) and many more products for this protein.

Gene Name	GeneID	UniProt
AAAS	300259
AAAS	8086	Q9NRG9
AAAS	223921	P58742

How to order from antibodies-online

+1 877 302 8632
+1 888 205 9894 (toll-free)
Order online
orders@antibodies-online.com

Top anti-Adracalin Antibodies at antibodies-online.com

Showing 10 out of 61 products:

Catalog No.	Reactivity	Host	Conjugate	Application	Quantity	Supplier	Delivery	Price	Details
ABIN2704453	Human	Rabbit	Un-conjugated	WB	200 μL	Log in to see	13 to 14 Days	$487.50	Details
ABIN396498	Human	Mouse	Un-conjugated	ELISA, IHC, WB	100 μg	Log in to see	8 to 11 Days	$461.00	Details
ABIN2854764	Human	Rabbit	Un-conjugated	ICC, IF, IHC (p), WB	100 μL	Log in to see	1 to 2 Days	$358.60	Details
ABIN790611	Human	Mouse	Un-conjugated	ELISA, IHC, IHC (p), WB	50 μg	Log in to see	7 to 9 Days	$727.83	Details
ABIN563541	Human	Mouse	Un-conjugated	IHC (p), ELISA, WB	100 μg	Log in to see	11 to 12 Days	$440.00	Details
ABIN3187610	Human	Rabbit	Un-conjugated	ELISA, WB	100 μL	Log in to see	16 Days	$181.73	Details
ABIN5535164	Human	Rabbit	Un-conjugated	WB	200 μL	Log in to see	2 to 3 Days	$515.63	Details
ABIN521758	Human	Mouse	Un-conjugated	WB	50 μL	Log in to see	11 to 12 Days	$440.00	Details
ABIN2715861	Human	Mouse	Un-conjugated	IHC, WB	0.1 mL	Log in to see	Available	$451.00	Details
ABIN4277090	Human	Rabbit	Un-conjugated	ICC, IF, IHC, IHC (p), WB	0.1 mL	Log in to see	8 to 11 Days	$514.63	Details

AAAS Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes	Applications	Host	Clonality	Conjugate
Rat (Rattus)	, ,	,	,	, , , , , , , , , , , , ,
Human	, , ,	,	,	, , , , , , , , , , , , ,
Mouse (Murine)	, , ,	,	,	, , , , , , , , , , , , ,

More product categories related to Adracalin Antibody

More Antibodies against Adracalin Interaction Partners

Human Achalasia, Adrenocortical Insufficiency, Alacrimia (AAAS) interaction partners

Clinical and genetic characteristics of six patients with triple A syndrome and AAAS mutations are described.
Nine different AAAS mutations were found, including one new mutation: c.755G>C, p.(Trp252Ser) in a French cohort of Triple A syndrome patients.
This study demonstrated that a single splicing mutation affects the AAAS transcripts and consequently the ALADIN protein structure and function.
Triple A syndrome with a novel indel mutation in the AAAS gene and delayed puberty.
down-regulating ALADIN results in decreased oxidative stress response leading to alteration in steroidogenesis, highlighting our knock-down cell model as an important in-vitro tool for studying the adrenal phenotype in triple A syndrome
Data suggest ALADIN is involved in resistance to oxidative stress in adrenocortical cells/neurons; ALADIN knockdown down-regulates StAR (steroidogenic acute regulatory protein (show STAR Antibodies)) and P45011beta (cytochrome P450 family 11 subfamily B polypeptide 1 (show CYP11B1 Antibodies)).
The compromising c.43C>A mutation is predicted to cause a p.Gln15Lys amino acid substitution in the ALADIN protein.
identification of two novel mutations in the AAAS gene associated with achalasia adrenocortical insufficiency alacrimia syndrome
Sequencing of the AAAS gene detected a compound heterozygous mutation consisting of a novel mutation p.Ser296Tyr (c.887C>A) in exon 9 and a previously described p.Ser263Pro (c.787T>C) missense mutation in exon 8 in both siblings triple A syndrome.
In all children with mutation in AAAS gene, regular follow up of adrenal function is necessary to avoid adrenal crisis and start substitution therapy as soon as adrenal insufficiency is noted.

Adracalin (AAAS) Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the WD-repeat family of regulatory proteins and may be involved in normal development of the peripheral and central nervous system. The encoded protein is part of the nuclear pore complex and is anchored there by NDC1. Defects in this gene are a cause of achalasia-addisonianism-alacrima syndrome (AAAS), also called triple-A syndrome or Allgrove syndrome. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with AAAS

aladin WD repeat nucleoporin (Aaas) antibody
achalasia, adrenocortical insufficiency, alacrimia (aaas) antibody
aladin WD repeat nucleoporin L homeolog (aaas.L) antibody
aladin WD repeat nucleoporin (AAAS) antibody
aladin WD repeat nucleoporin (aaas) antibody
achalasia, adrenocortical insufficiency, alacrimia (Aaas) antibody

AAA antibody
AAASb antibody
ADRACALA antibody
ADRACALIN antibody
ALADIN antibody
D030041N15Rik antibody
GL003 antibody
zgc:85873 antibody

Protein level used designations for AAAS

achalasia, adrenocortical insufficiency, alacrimia (Allgrove, triple-A) , aladin , Aladin , achalasia, adrenocortical insufficiency, alacrimia , aladin-like , Allgrove, triple-A , adracalin

GENE ID	SPECIES
300259	Rattus norvegicus
378454	Danio rerio
446908	Xenopus laevis
467003	Pan troglodytes
506561	Bos taurus
607867	Canis lupus familiaris
100063811	Equus caballus
100356621	Oryctolagus cuniculus
100405154	Callithrix jacchus
100468100	Ailuropoda melanoleuca
100485071	Xenopus (Silurana) tropicalis
100553207	Anolis carolinensis
100586295	Nomascus leucogenys
8086	Homo sapiens
223921	Mus musculus

Selected quality suppliers for anti-Adracalin (AAAS) Antibodies

Did you look for something else?

Phone:	+1 877 302 8632
Fax:	+1 888 205 9894 (Toll-free)
E-Mail:	orders@antibodies-online.com