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ACAD10 encodes a member of the acyl-CoA dehydrogenase family of enzymes (ACADs), which participate in the beta-oxidation of fatty acids in mitochondria. Additionally we are shipping ACAD10 Proteins (3) and and many more products for this protein.
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Six polymorphisms (rs12229654 at 12q24.1, rs671 of ALDH2 (show ALDH2 Antibodies), rs11066015 of ACAD10, rs2074356 and rs11066280 of HECTD4, and rs3782886 of BRAP (show BRAP Antibodies)) were found to be associated with both systolic and diastolic blood pressure, with those at 12q24.1 or in ACAD10 or BRAP (show BRAP Antibodies) being novel determinants of blood pressure in Japanese.
ACAD10 has significant activity towards the branched-chain substrates R and S, 2 methyl-C15-CoA and is highly expressed in fetal but not adult brain
Results propose that ACAD10 variation may increase type 2 diabetes susceptibility by impairing insulin (show INS Antibodies) sensitivity via abnormal lipid oxidation.
cDNA ACAD10 maps to chromosome 12q24.1
This gene encodes a member of the acyl-CoA dehydrogenase family of enzymes (ACADs), which participate in the beta-oxidation of fatty acids in mitochondria. The encoded enzyme contains a hydrolase domain at the N-terminal portion, a serine/threonine protein kinase catlytic domain in the central region, and a conserved ACAD domain at the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
acyl-Coenzyme A dehydrogenase family, member 10
, acyl-CoA dehydrogenase family, member 10
, acyl-CoA dehydrogenase family member 10-like
, acyl-CoA dehydrogenase family member 10