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Acyl-CoA Synthetase Long-Chain Family Member 6 Proteins (ACSL6)

The protein encoded by ACSL6 catalyzes the formation of acyl-CoA from fatty acids, ATP, and CoA, using magnesium as a cofactor. Additionally we are shipping Acyl-CoA Synthetase Long-Chain Family Member 6 Antibodies (61) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ACSL6 23305 Q9UKU0
ACSL6 117243 P33124
ACSL6 216739 Q91WC3
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Top Acyl-CoA Synthetase Long-Chain Family Member 6 Proteins at antibodies-online.com

Showing 5 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 60 Days
$9,371.15
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg 60 to 65 Days
$7,307.36
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
$888.80
Details
Wheat germ Human GST tag 10 μg 11 to 12 Days
$414.29
Details
Yeast Rat His tag   1 mg 60 to 71 Days
$3,890.33
Details

ACSL6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, , ,
Rat (Rattus)

Mouse (Murine)
,

More Proteins for Acyl-CoA Synthetase Long-Chain Family Member 6 (ACSL6) Interaction Partners

Human Acyl-CoA Synthetase Long-Chain Family Member 6 (ACSL6) interaction partners

  1. ACSL6 drives acyl-CoA toward lipid synthesis and its downregulation improves mitochondrial biogenesis, respiratory capacity and lipid oxidation

  2. variations in the ACSL6 gene may contribute to the quantity of cigarettes smoked

  3. The alternative fatty acid Gate-domain motifs are essential determinants for the activity of the human ACSL6 isoforms, which appear to act as homodimeric enzyme as well as in complex with other spliced forms.

  4. The t(5;12)(q23-31;p13)translocation with ETV6-ACSL6 genomic alteration rearrangement in polycythemia vera patients was reported.

  5. Analyses did not yield convincing evidence for associations of schizophrenia with ACSL6

  6. Three ACSL6 spliced variants of a mutually exclusive exon pair are reported, they encode a slightly different short motif which contains a conserved structural domain, the fatty acid Gate domain.

  7. haplotypes underlying the SPEC2/PDZ-GEF2/ACSL6 region are associated with schizophrenia

  8. The acyl-coenzyme A synthetase long-chain family member 6 (ACSL6) gene on chromosome 5q31 was associated with premature ovarian failure and identified disease-susceptibility haplotypes.

  9. ACSL6 is highly associated with schizophrenia and several haplotypes in this haploblock have about twofold to 10-fold increase in the affected subjects in Han Chinese.

Mouse (Murine) Acyl-CoA Synthetase Long-Chain Family Member 6 (ACSL6) interaction partners

  1. Acsl6 knockout mice demonstrate motor impairments, altered glutamate metabolism, and increased astrogliosis and microglia activation.

  2. variations in the ACSL6 gene may contribute to the quantity of cigarettes smoked

  3. Long-chain acyl-CoA synthetase expressed in brain participates in neuronal cell proliferation.

  4. Acsl6 promoter 1 (mAcsl6_pr1) region has a negative regulatory function

Acyl-CoA Synthetase Long-Chain Family Member 6 (ACSL6) Protein Profile

Protein Summary

The protein encoded by this gene catalyzes the formation of acyl-CoA from fatty acids, ATP, and CoA, using magnesium as a cofactor. The encoded protein plays a major role in fatty acid metabolism in the brain. Translocations with the ETV6 gene are causes of myelodysplastic syndrome with basophilia, acute myelogenous leukemia with eosinophilia, and acute eosinophilic leukemia. Several transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ACSL6

  • acyl-CoA synthetase long chain family member 6 (ACSL6)
  • acyl-CoA synthetase long-chain family member 6 (ACSL6)
  • acyl-CoA synthetase long chain family member 6 (acsl6)
  • acyl-CoA synthetase long-chain family member 6 (Acsl6)
  • acyl-CoA synthetase long-chain family member 6 (LOAG_15918)
  • acyl-CoA synthetase long-chain family member 6 (LOC416323)
  • acyl-CoA synthetase long chain family member 6 (Acsl6)
  • A330035H04Rik protein
  • ACS2 protein
  • ACSL6 protein
  • AW050338 protein
  • Facl6 protein
  • LACS protein
  • LACS2 protein
  • LACS5 protein
  • LACS 6 protein
  • Lacsl protein
  • MGC146229 protein
  • mKIAA0837 protein
  • wu:fa04h02 protein
  • wu:fc05h07 protein

Protein level used designations for ACSL6

fatty-acid-Coenzyme A ligase, long-chain 6 , long fatty acyl-CoA synthetase 2 , long-chain-fatty-acid--CoA ligase 6 , acyl-CoA synthetase long-chain family member 6 , acyl-CoA synthetase long-chain family member 6, isoform 2 , long-chain-fatty-acid--CoA ligase 6-like , LACS 6 , fatty acid Coenzyme A ligase, long chain 6 , long-chain acyl-CoA synthetase 6 , long-chain-fatty-acid--CoA ligase, brain isozyme , similar to Long-chain-fatty-acid--CoA ligase 6 (Long-chain acyl-CoA synthetase 6) (LACS 6)

GENE ID SPECIES
23305 Homo sapiens
416324 Gallus gallus
462044 Pan troglodytes
474670 Canis lupus familiaris
506059 Bos taurus
779783 Xenopus (Silurana) tropicalis
100063361 Equus caballus
100080087 Ornithorhynchus anatinus
100137537 Papio anubis
100229545 Taeniopygia guttata
100328719 Oryctolagus cuniculus
100411250 Callithrix jacchus
100445181 Pongo abelii
117243 Rattus norvegicus
216739 Mus musculus
9953413 Loa loa
100522126 Sus scrofa
100548919 Meleagris gallopavo
100553430 Anolis carolinensis
100592851 Nomascus leucogenys
416323 Gallus gallus
100718006 Cavia porcellus
566863 Danio rerio
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