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Acyltransferase that predominantly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Additionally we are shipping AWAT1 Kits (4) and AWAT1 Proteins (3) and many more products for this protein.
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analysis of AWAT1 and AWAT2 substrate specificity and differentiation-specific expression pattern
The highest activity was observed for 14:0-CoA, 12:0-CoA, and 16:0-CoA in combination with medium chain alcohols (up to 5.2, 3.4, and 3.3 nmol wax esters/min/mg microsomal protein, respectively
Acyltransferase that predominantly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that it plays a central role in lipid metabolism in skin. Has a preference for arachidyl alcohol as well as decyl alcohol, demonstrating its relatively poor activity using saturated long chain alcohols (C16, C18, and C20).
acyl-CoA wax alcohol acyltransferase 1
, diacylglycerol O-acyltransferase 2-like 3
, wax synthase 1
, diacyl-glycerol acyltransferase 2
, diacylglycerol O-acyltransferase 2-like protein 3
, diacylglycerol acyltransferase 2
, long-chain-alcohol O-fatty-acyltransferase 1