Acyloxyacyl Hydrolase (Neutrophil) Proteins (AOAH)

This locus encodes both the light and heavy subunits of acyloxyacyl hydrolase. Additionally we are shipping AOAH Antibodies (49) and AOAH Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat AOAH AOAH 498757  
AOAH 27052 O35298
AOAH 313 P28039
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Top AOAH Proteins at

Showing 6 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 50 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 50 Days
Wheat germ Human GST tag 2 μg 11 to 12 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
Yeast Rabbit His tag   1 mg 60 to 71 Days
Escherichia coli (E. coli) Human S tag,His tag 100 μg 15 to 18 Days

AOAH Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , , ,
, , ,

More Proteins for Acyloxyacyl Hydrolase (Neutrophil) (AOAH) Interaction Partners

Mouse (Murine) Acyloxyacyl Hydrolase (Neutrophil) (AOAH) interaction partners

  1. By inactivating commensal LPS, AOAH thus prevents desensitization of lung epithelial cells. An enzyme that prevents severe lung inflammation/injury in Gram-negative bacterial pneumonia has the seemingly paradoxical effect of predisposing to a Th2-mediated airway disease.

  2. AOAH modulates pelvic pain severity, suggesting that allelic variation in Aoah influences pelvic pain in interstitial cystitis.

  3. Alveolar macrophages increase AOAH expression upon exposure to lipopolysaccharide and that Aoah+/+ mice recover more rapidly than do Aoah-/- mice from acute lung injury induced by nasally instilled lipopolysaccharide or Klebsiella pneumonia.

  4. AOAH has a role in modulating microbiota signals that drive Th17 polarization and influence mucosal T-cell immunity

  5. role in clearing and catabolizing both free LPS and the LPS in circulating LPS-lipoprotein complexes

  6. produced by renal cortical tubule cells and secreted into urine, where it can deacylate lipopolysaccharides, a mechanism to limit inflammatory response to gram-negative bacteria in urinary tract

  7. Recovery from the tolerant state induced by Gram-negative bacteria is greatly delayed in in mice that lack AOAH, a lipase that partially deacylates the bacterial cell-wall lipopolysaccharide.

Human Acyloxyacyl Hydrolase (Neutrophil) (AOAH) interaction partners

  1. analysis of AOAH function through its crystal structure and complex with lipopolysaccharide

  2. AOAH - Gene involved in innate immunity that have been associated with Chronic Rhinosinusitis.

  3. AOAH rs60023210 variants may be associated with carotid intima-media thickness at bifurcation.

  4. Polymorphisms in RYBP and AOAH genes are associated with chronic rhinosinusitis in a Chinese population.

AOAH Protein Profile

Protein Summary

This locus encodes both the light and heavy subunits of acyloxyacyl hydrolase. The encoded enzyme catalyzes the hydrolysis of acyloxylacyl-linked fatty acyl chains from bacterial lipopolysaccharides, effectively detoxifying these molecules. The encoded protein may play a role in modulating host inflammatory response to gram-negative bacteria. Alternatively spliced transcript variants have been described.

Gene names and symbols associated with AOAH

  • acyloxyacyl hydrolase (AOAH)
  • acyloxyacyl hydrolase (Aoah)
  • acyloxyacyl hydrolase (aoah)
  • 4930433E13Rik protein
  • MGC142308 protein
  • RGD1560514 protein

Protein level used designations for AOAH

acyloxyacyl hydrolase (neutrophil) , acyloxyacyl hydrolase , acyloxyacyl hydrolase-like

420737 Gallus gallus
463352 Pan troglodytes
482402 Canis lupus familiaris
498757 Rattus norvegicus
706291 Macaca mulatta
768208 Bos taurus
100055508 Equus caballus
100456260 Pongo abelii
100471433 Ailuropoda melanoleuca
100522290 Sus scrofa
100554361 Anolis carolinensis
27052 Mus musculus
313 Homo sapiens
100008662 Oryctolagus cuniculus
Selected quality suppliers for AOAH Proteins (AOAH)
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