Adaptor Related Protein Complex 4 sigma 1 Proteins (AP4s1)

This gene encodes a member of the adaptor complexes small subunit protein family. These proteins are components of the heterotetrameric adaptor protein complexes, which play important roles in the secretory and endocytic pathways by mediating vesicle formation and sorting of integral membrane proteins. The encoded protein is the small subunit of adaptor protein complex-4, which is associated with both clathrin- and nonclathrin-coated vesicles. Mutations in this gene are associated with spastic quadriplegic cerebral palsy-6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6.

• adaptor related protein complex 4 sigma 1 subunit (AP4S1)
• adaptor-related protein complex 4, sigma 1 subunit (Ap4s1)
• adaptor-related protein complex AP-4, sigma 1 (Ap4s1)

• AI314282 protein
• AP47B protein
• CLA20 protein
• CLAPS4 protein
• CPSQ6 protein
• Show all synonym aliases
• SPG52 protein

AP-4 adapter complex subunit sigma-1 , AP-4 complex subunit sigma-1 , clathrin-associated/assembly/adaptor protein, sigma 4 , sigma-4-adaptin , adapter-related protein complex 4 subunit sigma-1 , sigma-1 subunit of AP-4 , sigma4-adaptin , adaptor-related protein complex AP-4, sigma 1