Adenomatosis Polyposis Coli Down-Regulated 1 Proteins (APCDD1)

This locus encodes an inhibitor of the Wnt signaling pathway. Additionally we are shipping APCDD1 Antibodies (36) and APCDD1 Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
APCDD1 147495 Q8J025
APCDD1 494504 Q3U128
Rat APCDD1 APCDD1 689616  
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Top APCDD1 Proteins at antibodies-online.com

Showing 7 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg 50 to 55 Days
$7,493.38
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg 50 to 55 Days
$5,262.31
Details
Human Cells Human Fc Tag 100 μg 14 to 16 Days
$505.35
Details
Wheat germ Human GST tag 2 μg 11 to 12 Days
$338.33
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
$888.80
Details
Yeast Xenopus laevis His tag   1 mg 60 to 71 Days
$3,294.50
Details
Yeast REACT_Pelodiscus sinensis japonicus His tag   1 mg 60 to 71 Days
$3,322.00
Details

APCDD1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , , , ,
Mouse (Murine)
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More Proteins for Adenomatosis Polyposis Coli Down-Regulated 1 (APCDD1) Interaction Partners

Human Adenomatosis Polyposis Coli Down-Regulated 1 (APCDD1) interaction partners

  1. Through integrative analysis, we identify MEIS1 as a super-enhancer-driven oncogene, which co-operates with EWS-FLI1 in transcriptional regulation, and plays a key pro-survival role in Ewing sarcoma. Moreover, APCDD1, another super-enhancer-associated gene, acting as a downstream target of both MEIS1 and EWS-FLI1, is also characterized as a novel tumor-promoting factor in this malignancy

  2. Thus, we have provided the first evidence that APCDD1 expression is epigenetically silenced in OS, which may facilitate invasion and metastasis of OS cells.

  3. these novel findings suggest that APCDD1 positively regulates adipogenic differentiation and that its down-regulation by miR-130 during diet-induced obesity may contribute to impaired adipogenic differentiation and obesity-related metabolic disease.

  4. This study demonstrated a critical role for Apcdd1 in OL differentiation after white matter injury that points to a potential therapeutic approach for inhibiting Wnt signaling in these disorders.

  5. Unusual role of APCDD1 in dental follicle cells during osteogenic differentiation. APCDD1 sustains the expression and activation of beta-catenin.

  6. mutation in the APCDD1 gene is responsible for hereditary hypotrichosis simplex in a large Chinese family.

  7. Data show that the methylated VAPA-APCDD1 DNA in maternal plasma is predominantly derived from the fetus, and this novel fetal epigenetic marker in maternal plasma is useful for the noninvasive detection of fetal trisomy 18.

  8. APCDD1 is a novel inhibitor of the Wnt signalling pathway with an essential role in human hair growth

Mouse (Murine) Adenomatosis Polyposis Coli Down-Regulated 1 (APCDD1) interaction partners

  1. these novel findings suggest that APCDD1 positively regulates adipogenic differentiation and that its down-regulation by miR-130 during diet-induced obesity may contribute to impaired adipogenic differentiation and obesity-related metabolic disease.

  2. Suggest that APCDD1 modulates the gene expression of Wnt- and EK-related signaling molecules at the cap stage of tooth development, and is involved in tooth cusp patterning by modulating epithelial rearrangement.

  3. mouse Drapc1 is a novel in vivo target gene of Wnt/beta-catenin signaling pathway

APCDD1 Protein Profile

Protein Summary

This locus encodes an inhibitor of the Wnt signaling pathway. Mutations at this locus have been associated with hereditary hypotrichosis simplex. Increased expression of this gene may also be associated with colorectal carcinogenesis.

Gene names and symbols associated with APCDD1

  • adenomatosis polyposis coli down-regulated 1 (apcdd1)
  • APC down-regulated 1 (APCDD1)
  • adenomatosis polyposis coli down-regulated 1 (Apcdd1)
  • APC down-regulated 1 (Apcdd1)
  • adenomatosis polyposis coli down-regulated 1 L homeolog (apcdd1.L)
  • AB023957 protein
  • APCDD1 protein
  • AU041258 protein
  • B7323 protein
  • cAPCDD1 protein
  • Drapc1 protein
  • EIG180 protein
  • HHS protein
  • HTS protein
  • Pgo1 protein
  • xPgo protein

Protein level used designations for APCDD1

Adenomatosis polyposis coli down-regulated 1 protein homolog , protein APCDD1 , adenomatosis polyposis coli down-regulated 1 , protein APCDD1-like , APCDD1 homologue , adenomatosis polyposis coli down-regulated 1 protein homolog , primglo1 , protein primglo1 , adenomatosis polyposis coli down-regulated 1 protein , hypoptrichosis simplex , ethanol induced gene product EIG180 , Protein primglo

GENE ID SPECIES
448576 Xenopus (Silurana) tropicalis
455287 Pan troglodytes
509040 Bos taurus
100017299 Monodelphis domestica
100459972 Pongo abelii
100479490 Ailuropoda melanoleuca
100603521 Nomascus leucogenys
426765 Gallus gallus
147495 Homo sapiens
494504 Mus musculus
480209 Canis lupus familiaris
689616 Rattus norvegicus
447402 Xenopus laevis
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